Job Description Q8IR23 Confidence 48.61% Date Tue Jan 22 11:23:02 GMT 2013 Rank 321 Aligned Residues 164 % Identity 17% Template c1e8zA_ PDB info PDB header:transferase Chain: A: PDB Molecule:phosphatidylinositol 3-kinase catalytic subunit; PDBTitle: structure determinants of phosphoinositide 3-kinase2 inhibition by wortmannin, ly294002, quercetin, myricetin3 and staurosporine Resolution 2.40 Å

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		501	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.					.	.	.	.	.	.	.	530	.	.	.			.	.	.	.	.	.	540	.	.	.		.	.	.	.	.	.	550	.	.	.					.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																								.	.	.	.												.	.											.											.	.	.	.
Query SS confidence																								.	.	.	.												.	.											.											.	.	.	.
Query Sequence		L	R	C	L	N	L	H	V	L	E	A	H	R	L	P	F	K	L	V	P	H	P	.	.	.	.	Y	C	S	I	S	L	N	Q	V	K	V	.	.	G	K	T	R	V	K	I	A	P	E	.	P	V	W	E	E	E	F	V	L	D	.	.	.	.	D	V	P	P	D	V	V	S	L	T	I	T	L	I	S	R
Query Conservation																								.	.	.	.												.	.											.											.	.	.	.
Alig confidence																								.	.	.	.												.	.											.											.	.	.	.					.											.
Template Conservation																																																																						.											.
Template Sequence		D	R	K	F	R	V	K	I	R	G	I	D	I	P	V	L	P	R	N	T	D	L	T	V	F	V	E	A	N	I	Q	H	G	Q	Q	V	L	C	Q	R	R	T	S	P	K	P	F	T	E	E	V	L	W	N	V	W	L	E	F	S	I	K	I	K	D	L	P	K	.	G	A	L	L	N	L	Q	I	Y	C	.
Template Known Secondary structure			S												S					S	S													T	T															S														G	G	G			T	.	T										.
Template Predicted Secondary structure																																																																						.											.
Template SS confidence
		358	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.		.	.	.	.	430	.	.	.	.	.
		570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.					.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.									.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.					.	.	.	.	.	630	.	.	.
Predicted Secondary structure																		.	.	.	.																					.	.	.	.	.	.	.	.																				.	.	.	.
Query SS confidence																		.	.	.	.																					.	.	.	.	.	.	.	.																				.	.	.	.
Query Sequence		G	K	R	G	K	D	S	E	V	A	E	L	T	I	D	L	.	.	.	.	S	S	L	K	N	G	Q	E	T	E	G	W	Y	Q	L	T	G	M	T	P	.	.	.	.	.	.	.	.	M	G	E	W	G	S	L	R	L	R	M	R	Y	L	D	D	L	I	M	.	.	.	.	P	C	E	E	Y	S	P	L	Q
Query Conservation																		.	.	.	.																					.	.	.	.	.	.	.	.																				.	.	.	.
Alig confidence		.	.	.	.	.	.	.										.	.	.	.																					.	.	.	.	.	.	.	.																				.	.	.	.
Template Conservation		.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	L	L	Y	Y	V	N	L	L	L	I	D	H	R	F	L	L	R	R	G	E	Y	V	L	H	M	W	Q	I	S	G	F	N	A	D	K	L	T	S	A	T	N	P	D	K	E	N	S	M	S	I	S	I	L	L	D	N	H	P	I	A	R	A	E	M	P	N	Q	L	R	K	Q	L	E
Template Known Secondary structure		.	.	.	.	.	.	.									S	B		T	T	S		B										B							G	G	G	G						S		T	T	T	S
Template Predicted Secondary structure		.	.	.	.	.	.	.
Template SS confidence
									460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.
		634	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	L	L	L	E	S	E	L	Y	A	V	K	A	L	A	E	L	C	H	N	D	R	V	P	L	A	T	A	L	L	R	V	F	R	Q	E	K	R	E	T	E	L	I	R	M	L
Query Conservation
Alig confidence															.	.	.	.	.	.
Template Conservation															.	.	.	.	.	.
Template Sequence		A	I	I	A	T	D	P	L	N	P	L	T	A	.	.	.	.	.	.	E	D	K	E	L	L	W	H	F	R	Y	E	S	L	K	H	P	K	A	Y	P	K	L	F	S	S	V
Template Known Secondary structure						S		T	T	S					.	.	.	.	.	.									T					T	T		G	G	G						T	T	S
Template Predicted Secondary structure															.	.	.	.	.	.
Template SS confidence
		557	.	.	560	.	.	.	.	.	.	.	.	.							570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions