Job Description Q24145 Confidence 100.00% Date Tue Jan 22 11:35:34 GMT 2013 Rank 75 Aligned Residues 244 % Identity 30% Template c3vw6B_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor Resolution 2.40 Å

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		653	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	R	F	F	I	E	P	E	K	L	V	L	D	R	E	I	G	H	G	E	F	G	S	V	H	S	G	W	L	L	R	K	S	G	A	G	E	E	S	R	L	E	V	A	I	K	M	L	S	D	E	H	S	N	K	Q	E	F	L	R	E	A	S	V	M	M	R	L	E	H	K	C	I	V	R	L	I	G	I	A
Query Conservation
Alig confidence																														.	.	.	.	.	.	.																	.	.	.	.	.
Template Conservation																														.	.	.	.	.	.	.																	.	.	.	.	.
Template Sequence		L	E	Y	D	Y	E	Y	D	E	N	G	D	R	V	V	L	G	K	G	T	Y	G	I	V	Y	A	G	R	.	.	.	.	.	.	.	D	L	S	N	Q	V	R	I	A	I	K	E	I	P	E	Q	.	.	.	.	.	P	L	H	E	E	I	A	L	H	K	H	L	K	H	K	N	I	V	Q	Y	L	G	S	F
Template Known Secondary structure								B		T	T	S	S	B							S	S	S							.	.	.	.	.	.	.		T	T	T													.	.	.	.	.										T	T				T	T	B
Template Predicted Secondary structure																														.	.	.	.	.	.	.																	.	.	.	.	.
Template SS confidence
		671	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.								.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.						.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.
		733	.	.	.		.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.		760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.		.	.	800	.	.	.	.	.	.	.	.	.
Predicted Secondary structure						.																								.																																							.
Query SS confidence						.																								.																																							.
Query Sequence		K	G	E	M	.	L	M	M	V	Q	E	L	A	P	L	G	S	M	L	Q	Y	I	L	D	H	G	H	E	.	I	T	A	N	A	E	L	K	V	W	A	S	Q	I	A	C	G	M	H	Y	L	E	S	Q	H	F	V	H	R	D	L	A	A	R	N	I	L	L	.	T	A	R	H	Q	A	K	I	S	D	F	G
Query Conservation						.																								.																																							.
Alig confidence						.																								.																																							.
Template Conservation
Template Sequence		S	E	N	G	F	I	K	I	F	M	E	Q	V	P	G	G	S	L	S	A	L	L	R	S	K	W	G	P	L	K	D	N	E	Q	T	I	G	F	Y	T	K	Q	I	L	E	G	L	K	Y	L	H	D	N	Q	I	V	H	R	D	I	K	G	D	N	V	L	I	N	T	Y	S	G	V	L	K	I	S	D	F	G
Template Known Secondary structure				T	T										T	T		B								T	T				T	T																						T	T				S			S	G	G	G					T	T	T									S
Template Predicted Secondary structure
Template SS confidence
		745	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.
		810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.			.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.			.	.	880	.	.	.	.	.
Predicted Secondary structure																																				.	.																																			.	.
Query SS confidence																																				.	.																																			.	.
Query Sequence		M	S	R	S	L	R	P	G	S	T	E	Y	Q	F	T	Q	G	G	R	W	P	I	R	W	Y	A	P	E	S	F	N	L	G	I	.	.	F	S	H	A	S	D	V	W	S	F	G	V	T	I	W	E	M	F	S	L	G	A	P	P	Y	G	E	I	S	N	V	D	A	I	.	.	K	L	V	D	S	G	E	R
Query Conservation																																				.	.																																			.	.
Alig confidence								.	.	.	.	.	.	.	.	.	.	.	.	.																.	.																				.															.	.
Template Conservation								.	.	.	.	.	.	.	.	.	.	.	.	.																																					.
Template Sequence		T	S	K	R	L	T	.	.	.	.	.	.	.	.	.	.	.	.	.	G	T	L	Q	Y	M	A	P	E	I	I	D	K	G	P	R	G	Y	G	K	A	A	D	I	W	S	L	G	C	T	I	I	E	M	A	T	.	G	K	P	P	F	Y	E	L	G	E	P	Q	A	A	M	F	K	V	G	M	F	K	V	H
Template Known Secondary structure		S						.	.	.	.	.	.	.	.	.	.	.	.	.			G	G	G										G	G	G		S																		.	S	S		T	T	G	G	G		S												T
Template Predicted Secondary structure								.	.	.	.	.	.	.	.	.	.	.	.	.																																					.
Template SS confidence
		825	.	.	.	.	830														.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.		.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890
		886	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.			.	.	920	.	.
Predicted Secondary structure																																		.	.
Query SS confidence																																		.	.
Query Sequence		L	P	Q	P	N	L	C	P	A	Y	I	Y	A	V	M	Q	S	C	W	K	E	R	P	K	D	R	P	T	F	V	Y	L	.	.	T	E	F	F	A
Query Conservation																																		.	.
Alig confidence																																		.	.
Template Conservation
Template Sequence		P	E	I	P	E	S	M	S	A	E	A	K	A	F	I	L	K	C	F	E	P	D	P	D	K	R	A	C	A	N	D	L	L	V	D	E	F	L	K
Template Known Secondary structure						T	T	S												T		S		T	T	T	S								T	S	G	G	G
Template Predicted Secondary structure
Template SS confidence
		901	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions