Job Description Q24145 Confidence 100.00% Date Tue Jan 22 11:35:34 GMT 2013 Rank 105 Aligned Residues 251 % Identity 38% Template c3v5qB_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:nt-3 growth factor receptor; PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models Resolution 2.20 Å

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		657	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.		.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.		.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.
Predicted Secondary structure																			.																															.
Query SS confidence																			.																															.
Query Sequence		I	E	P	E	K	L	V	L	D	R	E	I	G	H	G	E	F	.	G	S	V	H	S	G	W	L	L	R	K	S	G	A	G	E	E	S	R	L	E	V	A	I	K	M	L	S	D	E	.	H	S	N	K	Q	E	F	L	R	E	A	S	V	M	M	R	L	E	H	K	C	I	V	R	L	I	G	I	A	K	G
Query Conservation																			.																															.
Alig confidence																			.								.	.	.	.	.	.	.																	.
Template Conservation																											.	.	.	.	.	.	.
Template Sequence		I	K	R	R	D	I	V	L	K	R	E	L	G	F	K	V	F	L	A	E	C	Y	N	L	S	.	.	.	.	.	.	.	P	T	K	D	K	M	L	V	A	V	K	A	L	K	D	P	T	L	A	A	R	K	D	F	Q	R	E	A	E	L	L	T	N	L	Q	H	E	H	I	V	K	F	Y	G	V	C	G	D
Template Known Secondary structure				G	G	G																		S			.	.	.	.	.	.	.	S	S	S	S											S																						T	T	B
Template Predicted Secondary structure																											.	.	.	.	.	.	.
Template SS confidence
		533	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.								.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.
		735	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	M	L	M	M	V	Q	E	L	A	P	L	G	S	M	L	Q	Y	I	L	D	H	G	H	E	I	T	A	N	A	E	L	K	V	W	A	S	Q	I	A	C	G	M	H	Y	L	E	S	Q	H	F	V	H	R	D	L	A	A	R	N	I	L	L	T	A	R	H	Q	A	K	I	S	D	F	G	M	S	R	S	L
Query Conservation
Alig confidence			.																						.
Template Conservation			.																						.
Template Sequence		P	.	L	I	M	V	F	E	Y	M	K	H	G	D	L	N	K	F	L	R	A	H	G	.	P	E	L	G	L	S	Q	M	L	H	I	A	S	Q	I	A	S	G	M	V	Y	L	A	S	Q	H	F	V	H	R	D	L	A	T	R	N	C	L	V	G	A	N	L	L	V	K	I	G	D	F	G	M	D	V	Y	S
Template Known Secondary structure			.									T	T									T	T		.																									T	T				S			S	G	G	G					G	G	G												S	G
Template Predicted Secondary structure			.																						.
Template SS confidence
		612		.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.		.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.
		815	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	P	G	S	T	E	Y	Q	F	T	Q	G	G	R	W	P	I	R	W	Y	A	P	E	S	F	N	L	G	I	F	S	H	A	S	D	V	W	S	F	G	V	T	I	W	E	M	F	S	L	G	A	P	P	Y	G	E	I	S	N	V	D	A	I	K	L	V	D	S	G	E	R	L	P	Q	P	N	L	C	P	A
Query Conservation
Alig confidence		.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	T	D	Y	Y	R	T	M	L	P	I	R	W	M	P	P	E	S	I	M	Y	R	K	F	T	T	E	S	D	V	W	S	F	G	V	I	L	W	E	I	F	T	Y	G	K	Q	P	W	F	Q	L	S	N	T	E	V	I	E	C	I	T	Q	G	R	V	L	E	R	P	R	V	C	P	K
Template Known Secondary structure		.	.	.	.	.	.	.	G	G		B				B		G	G	G																												T	T	T	S			T	T	T	T	S												T							T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.
Template SS confidence
									707	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.
		895	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	I	Y	A	V	M	Q	S	C	W	K	E	R	P	K	D	R	P	T	F	V	Y	L	T	E	F	F	A	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	V	Y	D	V	M	L	G	C	W	Q	R	E	P	Q	Q	R	L	N	I	K	E	I	Y	K	I	L	H	A
Template Known Secondary structure													S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		798	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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