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Job DescriptionQ24145
Confidence100.00%DateTue Jan 22 11:35:34 GMT 2013
Rank201Aligned Residues253
% Identity24%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   659660.........670.........680.........690.........700.........710.........720.........730.. .
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Query Sequence  PEKLVLDREIGHGEFGSVHSGWLLRKSGAGEESRLEVAIKMLSDEHSNKQEFLREASVMMRLEHKCIVRLIGIA. . . . . K
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Template Sequence  ARDITLLECVGKGRYGEVWRGSW. . . . . . . . . QGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHS
Template Known Secondary structure  TTTTT.........TT
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TTB

TT
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   205....210.........220....... ..230.........240.........250.........260.........270.....
 
   734.....740.........750.........760.........770.........780..... ....790.........800.....
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Query Sequence  GEMLMMVQELAPLGSMLQYILDHGHEITANAELKVWASQIACGMHYLESQHF. . . . . . . . VHRDLAARNILLTARHQAKI
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Template Sequence  STQLWLITHYHEMGSLYDYLQLTT. . . LDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCI
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TT
B

...B
S
B
STT
B

S

SGGG
TTS
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   276...280.........290......... 300.........310.........320.........330.........340.........350..
 
   806...810.........820..... ....830.........840... ......850.........860.........870...
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Query Sequence  SDFGMSRSLRPGSTEYQFTQ. GGRWPIRWYAPESFNLGI. . . . . . FSHASDVWSFGVTIWEMFSLGAPPYGEISN. . . . .
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Template Sequence  ADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPF
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TT
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TT


TT
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BTTB





TT
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   353......360.........370.........380.........390.........400.........410...... ...420.........430.
 
   874.....880.... .....890. ........900.........910.........920....
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Query Sequence  . . . . . . . . . . VDAIKLVDSGE. RLPQPNL. . . . . CPAYIYAVMQSCWKERPKDRPTFVYLTEFFARD
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Template Sequence  YDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
Template Known Secondary structure  TTTS
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TTS






GGGGGS

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   432.......440.........450.........460.........470.........480.........490........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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