Job Description Q24145 Confidence 100.00% Date Tue Jan 22 11:35:34 GMT 2013 Rank 173 Aligned Residues 247 % Identity 22% Template c3kvwA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity tyrosine-phosphorylation-regulated kinase PDBTitle: crystal structure of dual-specificity tyrosine phosphorylation2 regulated kinase 2 (dyrk2) in complex with an indirubin ligand Resolution 2.28 Å

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		660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.							.	.	.	.	.	.	.	730	.	.	.
Predicted Secondary structure																																																																	.	.	.	.	.	.
Query SS confidence																																																																	.	.	.	.	.	.
Query Sequence		E	K	L	V	L	D	R	E	I	G	H	G	E	F	G	S	V	H	S	G	W	L	L	R	K	S	G	A	G	E	E	S	R	L	E	V	A	I	K	M	L	S	D	E	H	S	N	K	Q	E	F	L	R	E	A	S	V	M	M	R	L	E	H	.	.	.	.	.	.	K	C	I	V	R	L	I	G	I	A	K
Query Conservation																																																																	.	.	.	.	.	.
Alig confidence																										.	.	.	.	.	.	.																																	.	.	.	.	.	.
Template Conservation																										.	.	.	.	.	.	.
Template Sequence		Y	R	Y	E	V	L	K	V	I	G	K	G	S	F	G	Q	V	V	K	A	Y	D	H	K	.	.	.	.	.	.	.	V	H	Q	H	V	A	L	K	M	V	R	N	E	K	R	F	H	R	Q	A	A	E	E	I	R	I	L	E	H	L	R	K	Q	D	K	D	N	T	M	N	V	I	H	M	L	E	N	F	T
Template Known Secondary structure		T	T										S	S	S									T	T	.	.	.	.	.	.	.	T	T										S																				T	T		T	T	S		S		B
Template Predicted Secondary structure																										.	.	.	.	.	.	.
Template SS confidence
		147	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170								.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.
		734	.	.		.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.			.	.	.	.	.	.	.	.	810
Predicted Secondary structure					.																																																																		.	.
Query SS confidence					.																																																																		.	.
Query Sequence		G	E	M	.	L	M	M	V	Q	E	L	A	P	L	G	S	M	L	Q	Y	I	L	D	H	G	H	E	I	T	A	N	A	E	L	K	V	W	A	S	Q	I	A	C	G	M	H	Y	L	E	S	Q	H	F	V	H	R	D	L	A	A	R	N	I	L	L	T	A	R	H	.	.	Q	A	K	I	S	D	F	G	M
Query Conservation					.																																																																		.	.
Alig confidence					.									.																																																									.	.
Template Conservation														.
Template Sequence		F	R	N	H	I	C	M	T	F	E	L	L	.	S	M	N	L	Y	E	L	I	K	K	N	K	F	Q	G	F	S	L	P	L	V	R	K	F	A	H	S	I	L	Q	C	L	D	A	L	H	K	N	R	I	I	H	C	D	L	K	P	E	N	I	L	L	K	Q	Q	G	R	S	G	I	K	V	I	D	F	G	S
Template Known Secondary structure			T	T										.			B								T	T	T																										T				S			S	G	G	G				S	S	T	T	S									T	T
Template Predicted Secondary structure														.
Template SS confidence
		220	.	.	.	.	.	.	.	.	.	230	.		.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.
		811	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.
Predicted Secondary structure																																																																															.	.	.
Query SS confidence																																																																															.	.	.
Query Sequence		S	R	S	L	R	P	G	S	T	E	Y	Q	F	T	Q	G	G	R	W	P	I	R	W	Y	A	P	E	S	F	N	L	G	I	F	S	H	A	S	D	V	W	S	F	G	V	T	I	W	E	M	F	S	L	G	A	P	P	Y	G	E	I	S	N	V	D	A	I	K	L	V	D	S	G	E	R	L	P	.	.	.
Query Conservation																																																																															.	.	.
Alig confidence								.	.	.	.	.	.	.																																								.																									.	.	.
Template Conservation								.	.	.	.	.	.	.																																								.
Template Sequence		S	C	Y	E	H	Q	.	.	.	.	.	.	.	R	V	Y	T	I	Q	S	R	F	Y	R	A	P	E	V	I	L	G	A	R	Y	G	M	P	I	D	M	W	S	L	G	C	I	L	A	E	L	L	T	.	G	Y	P	L	L	P	G	E	D	E	G	D	Q	L	A	C	M	I	E	L	L	G	M	P	S	Q	K
Template Known Secondary structure					T	T		.	.	.	.	.	.	.								G	G	G								T	B				T																	.	S	S		S	S			S	S
Template Predicted Secondary structure								.	.	.	.	.	.	.																																								.
Template SS confidence
		299	300	.	.	.	.								.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.		.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370
																																																						888	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Q	P	N	L	C	P	A	Y	I	Y	A	V	M	Q	S	C	W	K	E	R	P	K	D	R	P	T	F	V
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		L	L	D	A	S	K	R	A	K	N	F	V	S	K	G	Y	P	R	Y	C	T	V	T	T	L	S	D	V	V	L	N	G	G	R	S	R	R	G	K	L	R	G	P	P	E	S	R	E	W	G	N	A	L	K	G	C	D	D	P	L	F	L	D	F	L	K	Q	C	L	E	W	D	P	A	V	R	M	T	P	G
Template Known Secondary structure					T	B	T	T					B					B	T	T	S																T	T						S	T	T		S						T	T	T														T		S	S	T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		372	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.
		916	.			.	.	920	.	.
Predicted Secondary structure				.	.
Query SS confidence				.	.
Query Sequence		Y	L	.	.	T	E	F	F	A
Query Conservation				.	.
Alig confidence				.	.
Template Conservation
Template Sequence		Q	A	L	R	H	P	W	L	R
Template Known Secondary structure					T	S	T	T	T
Template Predicted Secondary structure
Template SS confidence
		455	.	.	.	.	460	.	.	.

No model constructed - rank, confidence too low

---

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions