Return to main results Retrieve Phyre Job Id

Job DescriptionQ24145
Confidence100.00%DateTue Jan 22 11:35:34 GMT 2013
Rank176Aligned Residues240
% Identity38%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   654.....660.........670.........680.........690.........700.........710.........720.........730...
Predicted Secondary structure 































Query SS confidence 















































































Query Sequence  RFFIEPEKLVLDREIGHGEFGSVHSGWLLRKSGAGEESRLEVAIKMLSDEHSNKQEFLREASVMMRLEHKCIVRLIGIAK
Query Conservation     
          

 
 

 

 
               



 
            
  

  
 

 

 
     
Alig confidence 





























........








.......

























Template Conservation     
          

 
 

 
 
     ........   



 
.......
    

  
  
 




       
Template Sequence  SWEIDPKDLTFLKELGTGQFGVVKYGKWRG. . . . . . . . QYDVAIKMI. . . . . . . KEFIEEAKVMMNLSHEKLVQLYGVCT
Template Known Secondary structure  GGB

GGGSTTSS
TT........T
.......


TT


TTB


Template Predicted Secondary structure 






........

.......











Template SS confidence 















































































   394.....400.........410.........420... ......430.. .......440.........450........
 
   734.. ...740.........750.........760.........770.........780.........790.........800.........810..
Predicted Secondary structure 


.






























Query SS confidence 


.











































































Query Sequence  GEM. LMMVQELAPLGSMLQYILDHGHEITANAELKVWASQIACGMHYLESQHFVHRDLAARNILLTARHQAKISDFGMSR
Query Conservation     .   
 
    
 
   
                  

  

 


   






  



      

 



  
Alig confidence 


.






















.



















































Template Conservation         
        
          .                                            
 
     
Template Sequence  KQRPIFIITEYMANGCLLNYLREMRHR. FQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGFPV
Template Known Secondary structure  SSSS


TT
GGG
.

TT


S

SGGG
TT







G
Template Predicted Secondary structure 






















.
























Template SS confidence 















































































   466...470.........480.........490.. .......500.........510.........520.........530.........540....
 
   813......820.........830.........840.........850.........860.........870.........880.........890..
Predicted Secondary structure 







































Query SS confidence 















































































Query Sequence  SLRPGSTEYQFTQGGRWPIRWYAPESFNLGIFSHASDVWSFGVTIWEMFSLGAPPYGEISNVDAIKLVDSGERLPQPNLC
Query Conservation                        


           

 
 
    
    
  
                     
   
Alig confidence  ...................




























































Template Conservation  ...................                 

 
 
    

 
                 
            
Template Sequence  . . . . . . . . . . . . . . . . . . . RWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLA
Template Known Secondary structure  ...................GG





TTS

TTTTS
TT





TTS
Template Predicted Secondary structure  ...................









































Template SS confidence 















































































   562.......570.........580.........590.........600.........610.........620..
 
   893......900.........910.........920........
Predicted Secondary structure 











Query SS confidence 



































Query Sequence  PAYIYAVMQSCWKERPKDRPTFVYLTEFFARDPDYQ
Query Conservation            
    
  

    
           
Alig confidence 



































Template Conservation 
     

  

  

  


  


  
  

   
Template Sequence  SEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEE
Template Known Secondary structure 
TT
SSGGGS


Template Predicted Secondary structure 









Template SS confidence 



































   623......630.........640.........650........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions