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Job DescriptionQ24145
Confidence100.00%DateTue Jan 22 11:35:34 GMT 2013
Rank101Aligned Residues263
% Identity35%Templatec3fupB_
PDB info PDB header:transferaseChain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   653......660.........670.........680.........690.........700... ......710.........720.........730.
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Query Sequence  LRFFIEPEKLVLDREIGHGEFGSVHSGWLLRKSGAGEESRLEVAIKMLSDE. HSNKQEFLREASVMMRLEHKCIVRLIGI
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Template Sequence  DPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDN. . . TGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGV
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   840.........850.........860.........870.... .....880.........890.........900.........910......
 
   732.......740.........750.........760.........770.........780.........790.........800.........810.
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Query Sequence  AKGEMLMMVQELAPLGSMLQYILDHGHEITANAELKVWASQIACGMHYLESQHFVHRDLAARNILLTARHQAKISDFGMS
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Template Sequence  CY. SNLKLIMEYLPYGSLRDYL. QKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLT
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   917. .920.........930....... ..940.........950.........960.........970.........980.........990....
 
   812.......820.........830.........840.........850.........860.........870 .....
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Query Sequence  RSLRPGSTEYQFTQGGRWPIRWYAPESFNLGIFSHASDVWSFGVTIWEMFSLGAPPYGE. . . . . . . . . . . . . . . . ISNVD
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Template Sequence  KVL. . PQDKEKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFT. YIEKSKSPPAEFMRMIGNDKQGQMIVFH
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   9991000. ........1010.........1020.........1030.........1040....... ..1050.........1060.........1070.....
 
   876...880.........890.........900.........910.........920...
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Query Sequence  AIKLVDSGERLPQPNLCPAYIYAVMQSCWKERPKDRPTFVYLTEFFAR
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Template Sequence  LIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQ
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TT

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   1078.1080.........1090.........1100.........1110.........1120.....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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