Job Description Q24145 Confidence 100.00% Date Tue Jan 22 11:35:34 GMT 2013 Rank 69 Aligned Residues 264 % Identity 33% Template c3eygA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 1.90 Å

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		653	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	R	F	F	I	E	P	E	K	L	V	L	D	R	E	I	G	H	G	E	F	G	S	V	H	S	G	W	L	L	R	K	S	G	A	G	E	E	S	R	L	E	V	A	I	K	M	L	S	D	E	H	S	N	K	Q	E	F	L	R	E	A	S	V	M	M	R	L	E	H	K	C	I	V	R	L	I	G	I	A
Query Conservation
Alig confidence																																					.	.	.														.	.	.
Template Conservation																																					.	.	.														.	.	.
Template Sequence		D	P	T	H	F	E	K	R	F	L	K	R	I	R	D	L	G	E	G	H	F	G	K	V	E	L	C	R	Y	D	P	E	G	D	N	.	.	.	T	G	E	Q	V	A	V	K	S	L	K	P	H	.	.	.	I	A	D	L	K	K	E	I	E	I	L	R	N	L	Y	H	E	N	I	V	K	Y	K	G	I	C
Template Known Secondary structure			T	T	S			G	G	G											S	S										T	T	S	S	S	.	.	.		S												.	.	.													T				T	T	B
Template Predicted Secondary structure																																					.	.	.														.	.	.
Template SS confidence
		866	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900				.	.	.	.	.	.	.	.	.	910	.	.	.				.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.
		733	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	G	E	M	L	M	M	V	Q	E	L	A	P	L	G	S	M	L	Q	Y	I	L	D	H	G	H	E	I	T	A	N	A	E	L	K	V	W	A	S	Q	I	A	C	G	M	H	Y	L	E	S	Q	H	F	V	H	R	D	L	A	A	R	N	I	L	L	T	A	R	H	Q	A	K	I	S	D	F	G	M	S	R
Query Conservation
Alig confidence																											.
Template Conservation																											.
Template Sequence		T	E	N	G	I	K	L	I	M	E	F	L	P	S	G	S	L	K	E	Y	L	P	K	N	K	.	N	K	I	N	L	K	Q	Q	L	K	Y	A	V	Q	I	C	K	G	M	D	Y	L	G	S	R	Q	Y	V	H	R	D	L	A	A	R	N	V	L	V	E	S	E	H	Q	V	K	I	G	D	F	G	L	T	K
Template Known Secondary structure														T	T		B					T	G	G	G	T	.	T	T																							T	T				S			S	G	G	G						T	T								T	T
Template Predicted Secondary structure																											.
Template SS confidence
		945	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.		970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.
		813	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.																.	870	.	.	.	.	.	.	.
Predicted Secondary structure																																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		S	L	R	P	G	S	T	E	Y	Q	F	T	Q	G	G	R	W	P	I	R	W	Y	A	P	E	S	F	N	L	G	I	F	S	H	A	S	D	V	W	S	F	G	V	T	I	W	E	M	F	S	L	G	A	P	P	Y	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	E	I	S	N	V	D	A	I
Query Conservation																																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence				.	.																																															.						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation				.	.																																															.
Template Sequence		A	I	.	.	E	T	D	K	E	T	V	K	D	D	R	D	S	P	V	F	W	Y	A	P	E	C	L	M	Q	S	K	F	Y	I	A	S	D	V	W	S	F	G	V	T	L	H	E	L	L	T	.	Y	C	D	S	D	S	S	P	M	A	L	F	L	K	M	I	G	P	T	H	G	Q	M	T	V	T	R	L	V
Template Known Secondary structure				.	.		T	T					S			T	T			G	G	G																													T	.	T	T		G	G	G												S			G	G	G
Template Predicted Secondary structure				.	.																																															.
Template SS confidence
		1027	.			.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.		.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.
		878	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	L	V	D	S	G	E	R	L	P	Q	P	N	L	C	P	A	Y	I	Y	A	V	M	Q	S	C	W	K	E	R	P	K	D	R	P	T	F	V	Y	L	T	E	F	F	A	R	D	P	D
Query Conservation
Alig confidence
Template Conservation
Template Sequence		N	T	L	K	E	G	K	R	L	P	C	P	P	N	C	P	D	E	V	Y	Q	L	M	R	K	C	W	E	F	Q	P	S	N	R	T	S	F	Q	N	L	I	E	G	F	E	A	L	L	K
Template Known Secondary structure						T	T							T	T												T			S	S	G	G	G	S												T	T
Template Predicted Secondary structure
Template SS confidence
		1106	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions