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Job DescriptionQ24145
Confidence100.00%DateTue Jan 22 11:35:34 GMT 2013
Rank102Aligned Residues245
% Identity31%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   653......660.........670.........680.........690.........700... ......710.........720.........
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Query Sequence  LRFFIEPEKLVLDREIGHGEFGSVHSGWLLRKSGAGEESRLEVAIKMLSDE. . . HSNKQEFLREASVMMRLEHKCIVRLI
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Template Sequence  DDWEIPDGQITVGQRIGSGSFGTVYKGK. . . . . . . . . . WHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFM
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B

TT

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   448.450.........460.........470..... ....480.........490.........500.........510.......
 
   730.........740.........750.........760.........770.........780.........790.........800.........
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Query Sequence  GIAKGEMLMMVQELAPLGSMLQYILDHGHEITANAELKVWASQIACGMHYLESQHFVHRDLAARNILLTARHQAKISDFG
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Template Sequence  GYSTKPQLAIVTQWCEGSSLYHHLHIIETK. FEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFG
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   518.520.........530.........540....... ..550.........560.........570.........580.........590......
 
   810.........820.........830.........840... ......850.........860.........870..... ....880.....
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Query Sequence  MSRSLRPGSTEYQFTQGGRWPIRWYAPESFNLGI. . . FSHASDVWSFGVTIWEMFSLGAPPYGEISNVD. AIKLVDSGER
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Template Sequence  LATVL. . . . . . . . . . . . . SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMT. GQLPYSNINNRDQIIFMVGRGYL
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   597..600. ........610.........620.........630......... 640.........650.........660..
 
   886. ..890.........900.........910.........920..
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Query Sequence  LP. . . . QPNLCPAYIYAVMQSCWKERPKDRPTFVYLTEFFA
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Template Sequence  SPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIE
Template Known Secondary structure 


GGGS
TTS
T
SSGGGS

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   675....680.........690.........700.........710.....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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