|   |   |
660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | |
720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | |
. |
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
| . |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
| Query Sequence |   |
E | K | L | V | L | D | R | E | I | G | H | G | E | F | G | S | V | H | S | G | W | L | L | R | K | S | G | A | G | E | E | S | R | L | E | V | A | I | K | M | L | S | D | E | H | S | N | K | Q | E | F | L | R | E | A | S | V | M | M | R | . |
L | E | H | K | C | I | V | R | L | I | G | I | A | K | G | E | M | . |
L |
| Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   | . |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   | . |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
| Template Conservation |   |
  |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|
|
|   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   | . | . | . |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
D | G | Y | E | V | K | E | D | I | G | V | G | S | Y | S | V | C | K | R | C | I | . |
. |
. |
. |
. |
. |
. |
H | K | A | T | N | M | E | F | A | V | K | I | I | D | K | S | . |
. |
. |
K | R | D | P | T | E | E | I | E | I | L | L | R | Y | G | Q | H | P | N | I | I | T | L | K | D | V | Y | D | D | G | K | Y | V |
| Template Known Secondary structure |   |
T | T |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  | . | . | . | . | . | . | . |  | T | T | T | T |  |  |  |  |  |  |  |  |  | T | T | . | . | . | T |
|
| T |  |  |  |  |  |  |  |  |  |  | T | T | S | T | T | B |
|
|  |  |  |  |  |  |
| S | S |  |  |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |
|
|
|
|
|  |  |  |  |  |  |  |
|  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | |
|
|
. | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
738 | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | |
|
|
|
. | . | . | . | . | . | . | . | 810 | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . | . | . |  |  |  |  |
|
|
|
|
|  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
M | M | V | Q | E | L | A | P | L | G | S | M | L | Q | Y | I | L | D | H | G | H | E | I | T | A | N | A | E | L | K | V | W | A | S | Q | I | A | C | G | M | H | Y | L | E | S | Q | H | F | V | H | R | D | L | A | A | R | N | I | L | L | T | A | R | H | . |
. |
. |
. |
Q | A | K | I | S | D | F | G | M | S | R | S |
| Query Conservation |   |
  |   |
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   | . | . | . | . |   |   |
|
|   |
|
|
|
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
Y | V | V | T | E | L | M | K | G | G | E | L | L | D | K | I | L | R | Q | K | F | . |
. |
F | S | E | R | E | A | S | A | V | L | F | T | I | T | K | T | V | E | Y | L | H | A | Q | G | V | V | H | R | D | L | K | P | S | N | I | L | Y | V | D | E | S | G | N | P | E | S | I | R | I | C | D | F | G | F | A | K | Q |
| Template Known Secondary structure |   |
 |  |  |  |  |
|
|
| S |
| B |  |  |  |  |  |  | T |
| T | T | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
|
| G | G | G |  |  |  | S | S | S | S |
|
| G | G | G |  |  |  |
|
|
| T | T |
|  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | |
|
. | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . |
|   |
|   |   |
814 | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840 | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | . | . | . | . | . | 870 | . | . | . | |
|
|
. | . | . | . | . | . | 880 | . | . | . | . | . | . | . | . | |
|
| Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
| Query Sequence |   |
L | R | P | G | S | T | E | Y | Q | F | T | Q | G | G | R | W | P | I | R | W | Y | A | P | E | S | F | N | L | G | I | F | S | H | A | S | D | V | W | S | F | G | V | T | I | W | E | M | F | S | L | G | A | P | P | Y | G | E | I | S | N | . |
. |
. |
V | D | A | I | K | L | V | D | S | G | E | R | L | P | Q | . |
. |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |
| Alig confidence |   |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
| Template Conservation |   |
  |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |
|
|
|
|
|   |
| . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
L | R | A | E | N | . |
. |
. |
G | L | L | M | T | P | C | Y | T | A | N | F | V | A | P | E | V | L | E | R | Q | G | Y | D | A | A | C | D | I | W | S | L | G | V | L | L | Y | T | M | L | T | . |
G | Y | T | P | F | A | N | G | P | D | D | T | P | E | E | I | L | A | R | I | G | S | G | K | F | S | L | S | G | G |
| Template Known Secondary structure |   |
| B |
| T | T | . | . | . | S |
| B |
|
| S | S |
|
|
| S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
| S | S | T | T | S |
|  |  |  |  |  |  |  |  |  |  | T |
|
|
|
| S | S |  |
| Template Predicted Secondary structure |   |
 |
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
568 | . | 570 | . | . | |
|
|
. | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | |
. | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . |
|   |
|   |   |
|
889 | 890 | . | . | . | . | . | . | . | . | . | 900 | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | . | |
|
. | . | 920 | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | 930 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
. |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  | . | . |  |  |  |  |  | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
. |
P | N | L | C | P | A | Y | I | Y | A | V | M | Q | S | C | W | K | E | R | P | K | D | R | P | T | F | V | Y | L | . |
. |
T | E | F | F | A | . |
. |
. |
. |
. |
. |
. |
R | D | P | D | Y | Q | N | L | P | E | L | V | Q | T |
| Query Conservation |   |
. |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |
| . | . |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
Y | W | N | S | V | S | D | T | A | K | D | L | V | S | K | M | L | H | V | D | P | H | Q | R | L | T | A | A | L | V | L | R | H | P | W | I | V | H | W | D | Q | L | P | Q | Y | Q | L | N | R | Q | D | A | P | H | L | V | K | G |
| Template Known Secondary structure |   |
 |  |  | T | S |
|  |  |  |  |  |  |  |  |  |  | S |
| S | S | T | T | T | S |
|
|  |  |  |  |  | T | S |  |  |  |  | T | G | G | G | S |
|
| S |
|
|
|
|
|
|
|  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
644 | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . |
|   |