Job Description Q24145 Confidence 100.00% Date Tue Jan 22 11:35:34 GMT 2013 Rank 270 Aligned Residues 256 % Identity 20% Template c2pvmA_ PDB info PDB header:transferase Chain: A: PDB Molecule:casein kinase ii subunit alpha; PDBTitle: structure-based design of pyrazolo[1,5-a][1,3,5]triazine2 derivatives as potent inhibitors of protein kinase ck2 Resolution 2.00 Å

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		656	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	I	E	P	E	K	L	V	L	D	R	E	I	G	H	G	E	F	G	S	V	H	S	G	W	L	L	R	K	S	G	A	G	E	E	S	R	L	E	V	A	I	K	M	L	S	D	E	H	S	N	K	Q	E	F	L	R	E	A	S	V	M	M	R	L	E	H	K	C	I	V	R	L	I	G	I	A	K	G	E
Query Conservation
Alig confidence																														.	.	.	.	.	.	.														.	.
Template Conservation																														.	.	.	.	.	.	.														.	.
Template Sequence		W	G	E	Q	D	D	Y	E	V	V	R	K	V	G	R	G	K	Y	S	E	V	F	E	G	I	N	V	N	.	.	.	.	.	.	.	N	N	E	K	C	I	I	K	I	L	K	P	V	.	.	K	K	K	K	I	K	R	E	I	K	I	L	Q	N	L	G	G	P	N	I	V	K	L	L	D	I	V	R	D	Q
Template Known Secondary structure					G	G	G											S	S									T	T	.	.	.	.	.	.	.	T											S		.	.																		T	T	B										T
Template Predicted Secondary structure																														.	.	.	.	.	.	.														.	.
Template SS confidence
		33	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60								.	.	.	.	.	.	.	.	.	70	.	.	.			.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.
		736				.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800		.	.	.	.	.	.	.	.	.	810	.
Predicted Secondary structure			.	.	.																																																																	.
Query SS confidence			.	.	.																																																																	.
Query Sequence		M	.	.	.	L	M	M	V	Q	E	L	A	P	L	G	S	M	L	Q	Y	I	L	D	H	G	H	E	I	T	A	N	A	E	L	K	V	W	A	S	Q	I	A	C	G	M	H	Y	L	E	S	Q	H	F	V	H	R	D	L	A	A	R	N	I	L	L	T	A	R	.	H	Q	A	K	I	S	D	F	G	M	S
Query Conservation			.	.	.																																																																	.
Alig confidence			.	.	.																				.	.	.	.	.																																									.
Template Conservation																									.	.	.	.	.
Template Sequence		H	S	K	T	P	S	L	I	F	E	Y	V	N	N	T	D	F	K	V	L	Y	P	T	.	.	.	.	.	L	T	D	Y	D	I	R	Y	Y	I	Y	E	L	L	K	A	L	D	Y	C	H	S	Q	G	I	M	H	R	D	V	K	P	H	N	V	M	I	D	H	E	L	R	K	L	R	L	I	D	W	G	L	A
Template Known Secondary structure		T	T																			G	G	G	.	.	.	.	.																							T	T							S	G	G	G					T	T	T	T								T	T
Template Predicted Secondary structure																									.	.	.	.	.
Template SS confidence
		105	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.						.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.
		812	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.		.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																.																																							.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																.																																							.	.	.	.	.	.	.	.	.	.	.
Query Sequence		R	S	L	R	P	G	S	T	E	Y	Q	F	T	Q	G	G	R	W	P	I	R	W	Y	A	P	E	S	F	N	L	.	G	I	F	S	H	A	S	D	V	W	S	F	G	V	T	I	W	E	M	F	S	L	G	A	P	P	Y	G	E	I	S	N	V	D	A	I	K	L	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																.																																							.	.	.	.	.	.	.	.	.	.	.
Alig confidence								.	.	.	.																					.																																							.	.	.	.	.	.	.	.	.	.	.
Template Conservation								.	.	.	.
Template Sequence		E	F	Y	H	P	G	.	.	.	.	K	E	Y	N	V	R	V	A	S	R	Y	F	K	G	P	E	L	L	V	D	L	Q	D	Y	D	Y	S	L	D	M	W	S	L	G	C	M	F	A	G	M	I	F	R	K	E	P	F	F	Y	G	H	D	N	H	D	Q	L	V	K	I	A	K	V	L	G	T	D	G	L	N
Template Known Secondary structure						T	T	.	.	.	.					S			S		G	G	G							T	T			S			T																	T		S	S	S	S			S	S
Template Predicted Secondary structure								.	.	.	.
Template SS confidence
		180	.	.	.	.	.					.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.
																											880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.			.	.	920	.	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																							.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																							.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	V	D	S	G	E	R	L	P	Q	P	N	L	C	P	A	Y	I	Y	A	V	M	Q	S	C	W	K	E	R	P	K	D	R	P	T	F	V	Y	L	.	.	T	E	F	F	A	R	D	P	D	Y	Q	N
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																							.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																							.	.
Template Conservation
Template Sequence		A	Y	L	N	K	Y	R	I	E	L	D	P	Q	L	E	A	L	V	G	R	H	S	R	K	P	W	L	K	F	M	N	A	D	N	Q	H	L	V	S	P	E	A	I	D	F	L	D	K	L	L	R	Y	D	H	Q	E	R	L	T	A	L	E	A	M	T	H	P	Y	F	Q	Q	V	R	A	A	E	N
Template Known Secondary structure							T	T																			G	G	G	G			T	T	T	G	G	G											T	T			S	S	T	T	T	S									S	G	G	G								T
Template Predicted Secondary structure
Template SS confidence
		256	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions