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Job DescriptionQ24145
Confidence100.00%DateTue Jan 22 11:35:34 GMT 2013
Rank2Aligned Residues511
% Identity33%Templatec2ozoA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
Resolution2.60 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   8.10.........20...... ...30.........40.........50.........60.........70.........80......
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Query Sequence  MKWYHGNLSREAADELLKQ. GYEDGTFLVRESSTAAGDFVLSLLCQGEVCHYQVRRHGGEDAFFSIDDKVQTKILHGLDT
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Template Sequence  LPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQL. . NGTYAIAGGKA. . . HCGPAE
Template Known Secondary structure 
TTB
BS

TTT

TT
TTBTT
TT
T..TS
TTS

...BSS
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   8.10.........20.........30.........40.........50.........60..... ....70...... ...80..
 
   87..90.........100.........110..... ....120.........130.........140.........150.........
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Query Sequence  LVDYYQQAANGLPTKLTVPLIRDLPPHNT. . . . . . . RSHGVTNLLHRATSKNESKVVFELLKCGYRNFDAKNQDGQTALH
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Template Sequence  LCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVEKLI. . . . . . . . .
Template Known Secondary structure  TS

TTSSS


SB



TT


B




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   83......90.........100.........110.........120.........130.........140.........150...
 
   160.........170.........180.........190.........200.........210.........220.........230.........
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Query Sequence  LAALHSDEDILKHLLNAKVQVNSSDSFGCQPLHYAARSKPASFIRTLISAQANVQGRNIDNGYVPLHEAAKHGNLEAVQE
Query Conservation   
           

   
        
 
 
  
           

             
 
 
  
           
Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ................................................................................
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   240.........250.........260.........270.........280.........290.........300.........310.........
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Query Sequence  LLLAEAPPLPRTSSGEFPFDLAKEAGQTAVEEFLLNYKLPPANTTRDQWYHGTLTREEAVAILKKHAKELLAKQPEVDTS
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Template Conservation  .......................................         
 

 
 
 


  
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ATTAHERMPWYHSSLTREEAERKLY. . . . . . . . . . SGAQTD
Template Known Secondary structure  .......................................TTS
TTTSTTB
TT

S..........SS


T
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   154.....160.........170........ .180....
 
   320.........330.........340.........350.........360.........370.........380.........390.........
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Query Sequence  GCFLVRYSESPAASGLVLTLLCDQVVKNFRISQADLYQNGNKVQSGGSKFLYIDDGPYWPSVEHLIAHFMRFSYGLPVSL
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Template Sequence  GKFLLRPRKEQ. . GTYALSLIYGKTVYHYLI. . . . . . . . . . . . SQDKAGKYCIPEGTKFDTLWQLVEYLKLKADGLIYCL
Template Known Secondary structure  T

SST..TTT............
TT


TTS
SS

TT
SS

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   185....190..... ....200.........210... ......220.........230.........240.........250
 
   400.........410.........420.........430.........440.........450.........460.........470.........
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Query Sequence  KYPVPPQPKPEVPSFATIPRSNMKPKAASPATPPTPVSPHSHHQHPHVPALTITKKKQKENSSSMFNTLRLTSPKKALFD
Query Conservation    
  
      

    
               
                          

                 
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Template Conservation      ............................................................................
Template Sequence  KEAC. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure 
SB
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   251...
 
   480.........490.........500.........510.........520.........530.........540.........550.........
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Query Sequence  MNSLRKNKSKGKRSDSESSVSGSLAGTEQELQAAAPMLKSLSFSTEFSTFNADGVTGSGAAAAGEVYNVPRNNTPIEIDL
Query Conservation                    
 
 
   
       

       
   
            
                   
Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   560.........570.........580.........590.........600.........610.........620.........630.........
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Query Sequence  PPIAQKTEAEVEYFTKSDVAIERERAGQWIGNGYQPTMDVLSLLDQQIKAPAVARLNSLGPNASTESEMASYLHRKCSGT
Query Conservation                                                                                  
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Template Conservation  ........................................................................        
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PNMDTSVF
Template Known Secondary structure  ........................................................................





S
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   255....260..
 
   640.........650.........660.........670.........680.........690.........700... ......710.......
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Query Sequence  PSTPSATEVEAAKLRFFIEPEKLVLDREIGHGEFGSVHSGWLLRKSGAGEESRLEVAIKMLSDE. . HSNKQEFLREASVM
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Template Sequence  ESPFSDPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQ. . . . . IDVAIKVLKQGTEKADTEEMMREAQIM
Template Known Secondary structure  SSSSS
S
SS



SB

TTS
SSS
SS
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SSTT
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   316...320.........330.........340.........350.........360... ......370.........380.........390
 
   718.720.........730.........740.........750.........760.........770.........780.........790.......
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Query Sequence  MRLEHKCIVRLIGIAKGEMLMMVQELAPLGSMLQYILDHGHEITANAELKVWASQIACGMHYLESQHFVHRDLAARNILL
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Template Sequence  HQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREE. IPVSNVAELLHQVSMGMKYLEEKNFVHRNLAARNVLL
Template Known Secondary structure  TT


TTB

SSS

TT
BTT
TTT.S
TT


S

SGGG
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   391........400.........410.........420.........430.. .......440.........450.........460.........
 
   798.800.........810.........820.........830.........840.........850.........860.........870.......
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Query Sequence  TARHQAKISDFGMSRSLRPGSTEYQFTQGGRWPIRWYAPESFNLGIFSHASDVWSFGVTIWEMFSLGAPPYGEISNVDAI
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Template Sequence  VNRHYAKISDFGLSKAL. . . . . . . . . . . . . . GPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVM
Template Known Secondary structure  TT


STTTT
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TTS




TTS

TTTT

S
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   470.........480...... ...490.........500.........510.........520.........530.....
 
   878.880.........890.........900.........910.........920...
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Query Sequence  KLVDSGERLPQPNLCPAYIYAVMQSCWKERPKDRPTFVYLTEFFAR
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Template Conservation    
        
   
     

  
    
  

    
   
  
Template Sequence  AFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVEQRMRA
Template Known Secondary structure  TT





TT

TT
SSTTTS

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   550.........560.........570.........580.........590.....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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