|   |   |
665 | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | |
. | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | |
|
|
|
|
|
. | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
| Query Sequence |   |
D | R | E | I | G | H | G | E | F | G | S | V | H | S | G | W | L | L | R | K | S | G | A | G | E | E | S | R | L | E | V | A | I | K | M | L | S | D | E | . |
H | S | N | K | Q | E | F | L | R | E | A | S | V | M | M | R | L | E | H | K | C | I | V | R | L | I | G | I | A | K | G | E | . |
. |
. |
. |
. |
. |
M | L |
| Query Conservation |   |
  |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   | . |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |
| Alig confidence |   |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
| Template Conservation |   |
|   |   |
|
| . | . | . |
|
|   |
|
|   |
|   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
L | K | P | L | G | . |
. |
. |
N | G | L | V | F | S | A | V | . |
. |
. |
. |
. |
. |
. |
D | N | D | C | D | K | R | V | A | I | K | K | I | V | L | T | D | P | Q | S | V | K | H | A | L | R | E | I | K | I | I | R | R | L | D | H | D | N | I | V | K | V | F | E | I | L | G | P | S | G | S | Q | L | T | D | S | V |
| Template Known Secondary structure |   |
|  |  |
|
| . | . | . |
| T | T |  |  |  |  |  | . | . | . | . | . | . | . |  | T | T | T | T |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | B |
|
|  |  |  |  |  |
| S | S | S |
| B |
|
|
|
|  |
| Template Predicted Secondary structure |   |
|  |  |
|
| . | . | . |
|  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
23 | . | . | . | . | |
|
|
. | . | 30 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . |
|   |
|   |   |
738 | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
M | M | V | Q | E | L | A | P | L | G | S | M | L | Q | Y | I | L | D | H | G | H | E | I | T | A | N | A | E | L | K | V | W | A | S | Q | I | A | C | G | M | H | Y | L | E | S | Q | H | F | V | H | R | D | L | A | A | R | N | I | L | L | T | A | R | H | Q | A | K | I | S | D | F | G | M | S | R | S | L | R | P | G |
| Query Conservation |   |
  |   |
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
| Template Conservation |   |
  |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |
| Template Sequence |   |
Y | I | V | Q | E | Y | M | E | T | D | L | A | N | V | L | E | . |
. |
. |
. |
Q | G | P | L | L | E | E | H | A | R | L | F | M | Y | Q | L | L | R | G | L | K | Y | I | H | S | A | N | V | L | H | R | D | L | K | P | A | N | L | F | I | N | T | E | D | L | V | L | K | I | G | D | F | H | L | . |
. |
. |
. |
. |
. |
| Template Known Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  | T | . | . | . | . | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| S |
|
| S | G | G | G |  |  |  |  | T | T | T | T |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . |
| Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
105 | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | |
|
|
|
. | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | |
|
|
|
|
|
|   |
|   |   |
818 | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840 | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | . | . | . | . | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
| Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
| Query Sequence |   |
S | T | E | Y | Q | F | T | Q | G | G | R | W | P | I | R | W | Y | A | P | E | S | F | N | L | G | I | F | S | H | A | S | D | V | W | S | F | G | V | T | I | W | E | M | F | S | L | G | A | P | P | Y | G | E | I | S | N | V | D | A | I | K | L | V | D | S | G | E | R | L | P | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |
| Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
| Template Conservation |   |
. | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |
|   |   |   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
. |
. |
. |
. |
. |
. |
S | E | G | L | V | T | K | W | Y | R | S | P | R | L | L | L | S | P | N | N | Y | T | K | A | I | D | M | W | A | A | G | C | I | F | A | E | M | L | T | . |
G | K | T | L | F | A | G | A | H | E | L | E | Q | M | Q | L | I | L | E | S | I | P | V | V | H | E | E | D | R | Q | E | L | L | S |
| Template Known Secondary structure |   |
. | . | . | . | . | . | S | G | G | G | S |
|
| T | T |
|
|  |  |  |  |  | S | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
|
| S | S |  |  |  |  |  |  |  |  |  | T | T | S |
|
|
| S |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|
|
|
189 | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | |
. | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . |
|   |
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
889 | 890 | . | . | . | . | . | . | . | . | . | 900 | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | . | |
|
. | . | 920 | . | . | . |
| Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  | . | . |  |  |  |  |  |
|
| Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
| Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | N | L | C | P | A | Y | I | Y | A | V | M | Q | S | C | W | K | E | R | P | K | D | R | P | T | F | V | Y | L | . |
. |
T | E | F | F | A | R |
| Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |
| . | . |   |   |   |   |   |   |
| Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|
|
|
|   |
|
|
|   |
|
|   |   |   |   |
| Template Sequence |   |
V | I | P | V | M | T | E | P | H | K | P | L | T | Q | L | L | P | G | I | S | R | E | A | V | D | F | L | E | Q | I | L | T | F | S | P | M | D | R | L | T | A | E | E | A | L | S | H | P | Y | M | S | I |
| Template Known Secondary structure |   |
 |
|
|
|
|
| S |
| S | S |
|  |  |  |  | S | T | T |
|
|  |  |  |  |  |  |  |  | T | T | S |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  | S |  |  |  |  | T |
| Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
262 | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . |
|   |