Return to main results Retrieve Phyre Job Id

Job DescriptionQ24145
Confidence100.00%DateTue Jan 22 11:35:34 GMT 2013
Rank6Aligned Residues283
% Identity36%Templatec2h8hA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   640.........650.........660.........670.........680.........690.........700.........710.........
Predicted Secondary structure 







































Query SS confidence 















































































Query Sequence  PSTPSATEVEAAKLRFFIEPEKLVLDREIGHGEFGSVHSGWLLRKSGAGEESRLEVAIKMLSDEHSNKQEFLREASVMMR
Query Conservation                   
          

 
 

 

 
               



 
            
  

  
Alig confidence 











































........



























Template Conservation                   
          

 
 

 
       ........   



           
  
  

  
Template Sequence  CPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNG. . . . . . . . TTRVAIKTLKPGTMSPEAFLQEAQVMKK
Template Known Secondary structure 







SSSSTT
SB

GGG
SSTT........T
TTSS
Template Predicted Secondary structure 



























........







Template SS confidence 















































































   245....250.........260.........270.........280........ .290.........300.........310......
 
   720.........730.........740.........750.........760.........770.........780.........790.........
Predicted Secondary structure 
































Query SS confidence 















































































Query Sequence  LEHKCIVRLIGIAKGEMLMMVQELAPLGSMLQYILDHGHEITANAELKVWASQIACGMHYLESQHFVHRDLAARNILLTA
Query Conservation 
 

 

 
           
 
    
 
   
                  

  

 


   






  



  
Alig confidence 















































































Template Conservation 
 




 
 
        




   


   
                   
   
  

     
 

   


   
Template Sequence  LRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGE
Template Known Secondary structure 


TTB


SSS



TTSTT

TT


S

SGGG
G
Template Predicted Secondary structure 






































Template SS confidence 















































































   317..320.........330.........340.........350.........360.........370.........380.........390......
 
   800.........810.........820.........830.........840.........850.........860.........870.........
Predicted Secondary structure 



































Query SS confidence 















































































Query Sequence  RHQAKISDFGMSRSLRPGSTEYQFTQGGRWPIRWYAPESFNLGIFSHASDVWSFGVTIWEMFSLGAPPYGEISNVDAIKL
Query Conservation      

 



                        


           

 
 
    
    
  
            
Alig confidence 














..






























































Template Conservation      

 




   ..                  


       
 








 
 

 
 
  

           
Template Sequence  NLVCKVADFGLARLI. . EDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQ
Template Known Secondary structure  GG


TTSTTT
..

TT
STTS
GGGS




TTTT

SSTT

Template Predicted Secondary structure 











..




















Template SS confidence 















































































   397..400.........410. ........420.........430.........440.........450.........460.........470....
 
   880.........890.........900.........910.........920.........930..
Predicted Secondary structure 






















Query SS confidence 




















































Query Sequence  VDSGERLPQPNLCPAYIYAVMQSCWKERPKDRPTFVYLTEFFARDPDYQNLPE
Query Conservation           
             
    
  

    
               
Alig confidence 




















































Template Conservation 
  
     
   
  
  

  

   
  


   
   
        
  
Template Sequence  VERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQQ
Template Known Secondary structure  TT





TT

T
SSGGGS

TSS


S


Template Predicted Secondary structure 
























Template SS confidence 




















































   475....480.........490.........500.........510.........520.......
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions