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Job DescriptionP00528
Confidence100.00%DateTue Jan 22 11:25:29 GMT 2013
Rank8Aligned Residues372
% Identity37%Templatec4fl2A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch
Resolution2.19 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   158.160.........170.........180.........190.........200.........210.........220.........230.......
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Query Sequence  NSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSL
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Template Sequence  EKMPWFHGKISREESEQIVLIGSKTNGKFLIRARD. NNGSYALCLLH. . . . . EGKVLHYRIDKDKTGKLSIPEGKKFDTL
Template Known Secondary structure  GGSTTB

S

SSS

TT
.TTT.....TT
TTS
STT


BSS
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   164.....170.........180.........190........ .200......... 210.........220.........230.......
 
   238.240.........250.........260......... 270.........280......... 290.........300..
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Query Sequence  QALVMAYSKNALGLCHILSRPCPKPQPQMWDL. . . . . . . . . . . . . . GPELRDKYEIPRSEIQLLRK. LGRGNFGEVFYGK
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Template Sequence  WQLVEHYSYKADGLLRVLTVPCQKIGTQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGY
Template Known Secondary structure  TTB
TTSSS


SB


S


TT

GGGSGGGS
GGGSTTS


SSSB

GGGTT
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   238.240.........250.........260.........270.........280.........290.........300.........310.......
 
   303... ...310.........320 .........330.........340.........350.........360.........370......
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Query Sequence  WRNS. . . IDVAVKTLREGTMS. . . TAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYL
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Template Sequence  YQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGIC. EAESWMLVMEMAELGPLNKYLQQN. . RHV
Template Known Secondary structure  TT
SGGG
GGG


TTB

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TT
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   390.........400.........410.........420.........430......... 440.........450.........460... ...
 
   377..380.........390.........400.........410.........420.........430... ......440.........450....
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Query Sequence  HFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDE. . YCPKQGSRFPVKWTAPEAIIY
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Template Sequence  KDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINY
Template Known Secondary structure 
TT


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SGGGTT

TTTT

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BTTB
GGGG

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   467..470.........480.........490.........500.........510.........520.........530.........540......
 
   455....460.........470.........480.........490.........500.........510.........520.........530....
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Query Sequence  GKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNH
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Template Sequence  YKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAG. . CPREMYDLMNLCWTYDVENRPGFAAVEL
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TTT

SSTT

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TT..

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   547..550.........560.........570.........580.........590...... ...600.........610.........620....
 
   535....540
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Query Sequence  YFESFS
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Template Sequence  RLRNYY
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   625....630
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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