|   |   |
275 | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | |
. | . | . | 310 | . | . | . | . | . | . | . | . | |
. | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
| . |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | K | Y | E | I | P | R | S | E | I | Q | L | L | R | K | L | G | R | G | N | F | G | E | V | F | Y | G | K | W | R | N | S | . |
I | D | V | A | V | K | T | L | R | E | G | T | . |
M | S | T | A | A | F | L | Q | E | A | A | I | M | K | K | F | R | H | N | R | L | V | A | L | Y | A | V | C | S | Q | E | E | P | I |
| Query Conservation |   |
  |   |   |
|
|   |   |   |   |
|   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   |   |   | . |   |   |
|
|
|
|   |
|
|   |   |   | . |   |   |   |   |   |
|
|   |
|   |   |
|
|   |   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
P | H | R | I | F | R | P | S | D | L | I | H | G | E | V | L | G | K | G | C | F | G | Q | A | I | K | V | T | H | R | E | T | G | E | V | M | V | M | K | E | L | I | R | F | D | E | E | T | Q | R | T | F | L | K | E | V | K | V | M | R | C | L | E | H | P | N | V | L | K | F | I | G | V | L | Y | K | D | K | R | L |
| Template Known Secondary structure |   |
|
|  |  |  |
| G | G | G |  |  |  |  |  |  |  |  |
|
| S | S |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| T | T | B |
|
|  |  |  |  |  |  |  | T | T |  |  |
| Template Predicted Secondary structure |   |
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
353 | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | I | V | Q | E | Y | M | S | K | G | S | L | L | D | F | L | R | E | G | D | G | R | Y | L | H | F | E | D | L | I | Y | I | A | T | Q | V | A | S | G | M | E | Y | L | E | S | K | Q | L | I | H | R | D | L | A | A | R | N | V | L | I | G | E | N | N | V | A | K | I | C | D | F | G | L | A | R | V | I | A | D | D |
| Query Conservation |   |
  |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
N | F | I | T | E | Y | I | K | G | G | T | L | R | G | I | I | K | S | M | . |
D | S | Q | Y | P | W | S | Q | R | V | S | F | A | K | D | I | A | S | G | M | A | Y | L | H | S | M | N | I | I | H | R | D | L | N | S | H | N | C | L | V | R | E | N | K | N | V | V | V | A | D | F | G | L | A | R | L | M | V | Y | T |
| Template Known Secondary structure |   |
 |  |  |  |  |
|
| T | T |
| B |  |  |  |  |  |  |  |
| . |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
| S | T | T | S |  |  |  |
| T | T | S |
|  |  |  |
|
|
| T | T |
|  |  |
|
|
|
|
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | |
. | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . |
|   |
|   |   |
433 | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | Y | C | P | K | Q | G | S | R | F | P | V | K | W | T | A | P | E | A | I | I | Y | G | K | F | S | I | K | S | D | V | W | S | Y | G | I | L | L | M | E | L | F | T | Y | G | Q | V | P | Y | P | G | M | H | S | R | E | V | I | E | N | I | E | R | G | F | R | M | P | K | P | T | N | H | Y | F | P | D | N | I | Y |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |
|   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |
|   |   |
|   |
| Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
. | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |
|   |
|
|   |
| . |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
| Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
V | V | G | N | P | Y | W | M | A | P | E | M | I | N | G | R | S | Y | D | E | K | V | D | V | F | S | F | G | I | V | L | C | E | I | I | G | . |
R | V | N | A | D | P | D | Y | L | P | R | T | M | D | F | G | L | N | V | R | G | F | L | D | R | Y | C | P | P | N | C | P | P | S | F | F |
| Template Known Secondary structure |   |
. | . | . | . | . | . | . |
|
| S |
| G | G | G |
|
|  |  |  |  | T | T |
|
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | T |
|
| S | S | T | T | T | S |
| B |
| T | T | S | S | B |
|  |  |  |  |  |  |  | T |
|
| T | T |
|
| T | T |  |  |
| Template Predicted Secondary structure |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|
|
|
|
509 | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | |
. | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 |
|   |
|   |   |
513 | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Q | L | L | L | Q | C | W | D | A | V | P | E | K | R | P | T | F | E | F | L | N | H | Y | F | E | S | F |
| Query Conservation |   |
  |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|
|   |   |
|   |   |   |
|
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |
|
|   |   |   |
|   |   |
|
| Template Sequence |   |
P | I | T | V | R | C | C | D | L | D | P | E | K | R | P | S | F | V | K | L | E | H | W | L | E | T | L |
| Template Known Secondary structure |   |
 |  |  |  |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
581 | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . |
|   |