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Job DescriptionP00528
Confidence100.00%DateTue Jan 22 11:25:29 GMT 2013
Rank83Aligned Residues249
% Identity36%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   275....280.........290.........300.........310.........320. ........330.........340.........350.
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Query Sequence  DKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMST. . . AAFLQEAAIMKKFRHNRLVALYAVCSQEEP
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Template Sequence  DDWEIPDGQITVGQRIGSGSFGTVYKGKWHG. . DVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMG. YSTKPQ
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B

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   448.450.........460.........470........ .480.........490.........500.........510........ .520....
 
   352.......360.........370.........380.........390.........400.........410.........420.........430.
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Query Sequence  IYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIAD
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Template Sequence  LAIVTQWCEGSSLYHHLHII. ETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVL. .
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BTS.




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SGGGTTT


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   525....530.........540.... .....550.........560.........570.........580.........590.........600.
 
   432.......440.........450...... ...460.........470.........480........ .490.........500 .....
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Query Sequence  DEYCPKQGSRFPVKWTAPEAIIYGK. . . FSIKSDVWSYGILLMELFTYGQVPYPGMHSRE. VIENIERGFRMP. . KPTNH
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Template Sequence  . . . . . . . . . SGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMT. GQLPYSNINNRDQIIFMVGRGYLSPDLSKVRS
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   614.....620.........630.........640.........650. ........660.........670.........680...
 
   506...510.........520.........530.........
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Query Sequence  YFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESF
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Template Sequence  NCPKAMKRLMAECLKKKRDERPLFPQILASIELL
Template Known Secondary structure  TS
T
SSGGGS

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   684.....690.........700.........710.......
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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