Job Description P00528 Confidence 100.00% Date Tue Jan 22 11:25:29 GMT 2013 Rank 276 Aligned Residues 256 % Identity 21% Template c2pvmA_ PDB info PDB header:transferase Chain: A: PDB Molecule:casein kinase ii subunit alpha; PDBTitle: structure-based design of pyrazolo[1,5-a][1,3,5]triazine2 derivatives as potent inhibitors of protein kinase ck2 Resolution 2.00 Å

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		281	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.		.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.			.	.	.	.	.	.
Predicted Secondary structure																												.																																														.	.
Query SS confidence																												.																																														.	.
Query Sequence		R	S	E	I	Q	L	L	R	K	L	G	R	G	N	F	G	E	V	F	Y	G	K	W	R	N	S	.	I	D	V	A	V	K	T	L	R	E	G	T	M	S	T	A	A	F	L	Q	E	A	A	I	M	K	K	F	R	H	N	R	L	V	A	L	Y	A	V	C	S	Q	E	E	P	.	.	I	Y	I	V	Q	E
Query Conservation																												.																																														.	.
Alig confidence																												.												.	.																																	.	.
Template Conservation																																								.	.
Template Sequence		Q	D	D	Y	E	V	V	R	K	V	G	R	G	K	Y	S	E	V	F	E	G	I	N	V	N	N	N	E	K	C	I	I	K	I	L	K	P	V	.	.	K	K	K	K	I	K	R	E	I	K	I	L	Q	N	L	G	G	P	N	I	V	K	L	L	D	I	V	R	D	Q	H	S	K	T	P	S	L	I	F	E
Template Known Secondary structure		G	G	G											S	S									T	T	T											S		.	.																		T	T	B										T	T	T
Template Predicted Secondary structure																																								.	.
Template SS confidence
		36	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.			.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.
		358	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.		.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.
Predicted Secondary structure																																																									.
Query SS confidence																																																									.
Query Sequence		Y	M	S	K	G	S	L	L	D	F	L	R	E	G	D	G	R	Y	L	H	F	E	D	L	I	Y	I	A	T	Q	V	A	S	G	M	E	Y	L	E	S	K	Q	L	I	H	R	D	L	A	A	R	N	V	L	I	.	G	E	N	N	V	A	K	I	C	D	F	G	L	A	R	V	I	A	D	D	E	Y	C	P
Query Conservation																																																									.
Alig confidence																.	.	.	.	.																																					.
Template Conservation																.	.	.	.	.
Template Sequence		Y	V	N	N	T	D	F	K	V	L	Y	P	T	L	.	.	.	.	.	T	D	Y	D	I	R	Y	Y	I	Y	E	L	L	K	A	L	D	Y	C	H	S	Q	G	I	M	H	R	D	V	K	P	H	N	V	M	I	D	H	E	L	R	K	L	R	L	I	D	W	G	L	A	E	F	Y	H	P	G	K	E	Y	N
Template Known Secondary structure												G	G	G		.	.	.	.	.																						T	T							S	G	G	G					T	T	T	T								T	T						T	T
Template Predicted Secondary structure																.	.	.	.	.
Template SS confidence
		115	.	.	.	.	120	.	.	.	.	.	.	.	.						.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.
		437	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.		.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.
Predicted Secondary structure																				.																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																				.																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		K	Q	G	S	R	F	P	V	K	W	T	A	P	E	A	I	I	Y	.	G	K	F	S	I	K	S	D	V	W	S	Y	G	I	L	L	M	E	L	F	T	Y	G	Q	V	P	Y	P	G	M	H	S	R	E	V	I	E	N	I	E	R	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																				.																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence			.	.																.																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation			.	.
Template Sequence		V	.	.	R	V	A	S	R	Y	F	K	G	P	E	L	L	V	D	L	Q	D	Y	D	Y	S	L	D	M	W	S	L	G	C	M	F	A	G	M	I	F	R	K	E	P	F	F	Y	G	H	D	N	H	D	Q	L	V	K	I	A	K	V	L	G	T	D	G	L	N	A	Y	L	N	K	Y	R	I	E	L	D	P
Template Known Secondary structure		S	.	.			S		G	G	G							T	T			S			T																	T		S	S	S	S			S	S																								T	T
Template Predicted Secondary structure			.	.
Template SS confidence
		190			.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.
																496	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.			.	.	.	.	.	540	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.																																								.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.																																								.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	F	R	M	P	K	P	T	N	H	Y	F	P	D	N	I	Y	Q	L	L	L	Q	C	W	D	A	V	P	E	K	R	P	T	F	E	F	L	N	H	.	.	Y	F	E	S	F	S	V	T	S	E	V
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.																																								.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.																																								.	.
Template Conservation
Template Sequence		Q	L	E	A	L	V	G	R	H	S	R	K	P	W	L	K	F	M	N	A	D	N	Q	H	L	V	S	P	E	A	I	D	F	L	D	K	L	L	R	Y	D	H	Q	E	R	L	T	A	L	E	A	M	T	H	P	Y	F	Q	Q	V	R	A	A	E	N	S
Template Known Secondary structure															G	G	G	G			T	T	T	G	G	G											T	T			S	S	T	T	T	S									S	G	G	G								T
Template Predicted Secondary structure
Template SS confidence
		268	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions