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Job DescriptionP00528
Confidence100.00%DateTue Jan 22 11:25:29 GMT 2013
Rank7Aligned Residues372
% Identity38%Templatec2ozoA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
Resolution2.60 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   154.....160.........170.........180.........190.........200.........210.........220.........230...
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Query Sequence  ERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQT
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Template Conservation 
       
 

 


  

  
   
  

 



 
    
   

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Template Sequence  PDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVH. . . . . DVRFHHFPIERQLNGTYAIAGGKA
Template Known Secondary structure 

TTSS
TTB
BS

TTT

TT
TTBTT
.....TT
TTS
TTS

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   2.......10.........20.........30.........40.........50.. .......60.........70......
 
   234.....240.........250.........260.
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Query Sequence  FPSLQALVMAYSKNALGLCHILSRPCPK. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  HCGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATT
Template Known Secondary structure  BSSTS

TTSSS


SB



TT


B




TTS
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   77..80.........90.........100.........110.........120.........130.........140.........150......
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
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Template Sequence  AHERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLV
Template Known Secondary structure 
TTTSTTB
TT

SSS


TT

SSTTTT
TT


TTS
SS
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   157..160.........170.........180.........190.........200.........210.........220.........230......
 
   262.......270.........280.........290.........300...... ...310..
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . PQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNS. . . IDVAVK
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Template Conservation    
      
   
                                        

 
 

 
             



Template Sequence  EYLKLKADGLIYCLKEACPNMDTSVFESPFSDPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIK
Template Known Secondary structure 

TT
SS


SB






S
SSSSS
S
SS



SB

TTS
SSS
SS
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   237..240.........250.........260.........270.........280.........290.........300.........310......
 
   313...... 320.........330.........340.........350.........360.........370.........380.........390
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Query Sequence  TLREGTM. . STAAFLQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVAS
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Template Sequence  VLKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVC. QAEALMLVMEMAGGGPLHKFLVGKREE. IPVSNVAELLHQVSM
Template Known Secondary structure 




SSTTTT


TTB

.SSS

TT
BTT
TTT.S
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   370.........380.........390.........400..... ....410.........420.........430.. .......440.......
 
   391........400.........410.........420.........430.........440.........450.........460.........470
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Query Sequence  GMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILL
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Template Sequence  GMKYLEEKNFVHRNLAARNVLLVNRHYAKISDFGLSKAL. . . . . . . . . . . . GPLKWYAPECINFRKFSSRSDVWSYGVTM
Template Known Secondary structure  TT


S

SGGGTT


STTTT
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TTS




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   448.450.........460.........470.........480...... ...490.........500.........510.....
 
   471........480.........490.........500.........510.........520.........530.........540......
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Query Sequence  MELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESFSVTSEVP
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Template Sequence  WEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPE. . CPPELYALMSDCWIYKWEDRPDFLTVEQRMRACYYSLASK
Template Known Secondary structure  TTS

TTTT

STT





TT..

TT
SSTTTS

S
S
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   530.........540.........550.........560... ......570.........580.........590.........600...
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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