|   |   |
279 | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
I | P | R | S | E | I | Q | L | L | R | K | L | G | R | G | N | F | G | E | V | F | Y | G | K | W | R | N | S | I | D | V | A | V | K | T | L | R | E | G | T | M | S | T | A | A | F | L | Q | E | A | A | I | M | K | K | F | R | H | N | R | L | V | A | L | Y | A | V | C | S | Q | E | E | P | I | Y | I | V | Q | E | Y |
| Query Conservation |   |
|   |   |   |   |
|   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|
|   |   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|
|   |   |   |   |
| . |   |   |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|   |
|
|   |   |
|   |
|   |
|
|
|   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |
|   |
| Template Sequence |   |
F | D | E | R | P | I | S | V | G | G | N | K | G | E | G | G | F | G | V | V | Y | K | G | Y | V | N | N | . |
T | T | V | A | V | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | E | I | K | V | M | A | K | C | Q | H | E | N | L | V | E | L | L | G | F | S | . |
. |
. |
. |
. |
. |
C | L | V | Y | V | Y |
| Template Known Secondary structure |   |
T |
|
| S |
| G | G | G | T | S |
|
|
|  |  | T | T |  |  |
|  |  |  |  |  | T | T | . |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |
|
|
| T | T | B |
|
|  |  |  |  |
| . | . | . | . | . | . |
|  |  |  |  |
|
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
| . |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | |
. | . | . | 210 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . |
|   |
|   |   |
359 | 360 | . | . | . | . | . | . | . | . | . | 370 | |
. | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
M | S | K | G | S | L | L | D | F | L | R | E | . |
G | D | G | R | Y | L | H | F | E | D | L | I | Y | I | A | T | Q | V | A | S | G | M | E | Y | L | E | S | K | Q | L | I | H | R | D | L | A | A | R | N | V | L | I | G | E | N | N | V | A | K | I | C | D | F | G | L | A | R | V | I | A | D | D | E | Y | C | P | K |
| Query Conservation |   |
  |   |   |
|
|
|   |   |   |
|   |   | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
M | P | N | G | S | L | L | D | R | L | S | C | L | D | G | T | P | P | L | S | W | H | M | R | C | K | I | A | Q | G | A | A | N | G | I | N | F | L | H | E | N | H | H | I | H | R | D | I | K | S | A | N | I | L | L | D | E | A | F | T | A | K | I | S | D | F | G | L | A | R | A | S | E | V | M | R | I | V | G | T |
| Template Known Secondary structure |   |
| T | T |
| B |  |  |  |  |  | T | T | G | G | G |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
| S | G | G | G |  |  |  |
| T | T |
|
|  |  |  |
|
|
| S | S |
|  |  |
|
|
|
|
|
|
| S |
|
| Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
265 | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . |
|   |
|   |   |
438 | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Q | G | S | R | F | P | V | K | W | T | A | P | E | A | I | I | Y | G | K | F | S | I | K | S | D | V | W | S | Y | G | I | L | L | M | E | L | F | T | Y | G | Q | V | P | Y | P | G | M | H | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | E | V | I | E | N | I | E | R | G | F | R | M | P | K | P | T |
| Query Conservation |   |
  |   |   |   |   |   |
|   |
|   |
|
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |
|   |   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|   |
| Alig confidence |   |
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |
|   |   |   | . |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
T | . |
. |
. |
. |
. |
. |
. |
A | Y | M | A | P | E | A | L | R | G | E | I | T | P | K | S | D | I | Y | S | F | G | V | V | L | L | E | I | I | T | . |
G | L | P | A | V | D | E | H | R | E | P | Q | L | L | L | D | I | K | E | E | I | E | D | E | E | K | T | I | E | D | Y | I | D | K | K | M | N | D | A | D | S |
| Template Known Secondary structure |   |
G | . | . | . | . | . | . | . | G | G |
|
| T | T | T | T | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
| S | B |
| T | T | S | S | S | S | B | G | G | G |  |  |  |  |  |  | T | T | S | S |
|  |  |  |  | S |
| S | S |
| S |
|
|
|  |
| Template Predicted Secondary structure |   |
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
352 | |
|
|
|
|
|
|
. | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | |
. | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . |
|   |
|   |   |
504 | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
N | H | Y | F | P | D | N | I | Y | Q | L | L | L | Q | C | W | D | A | V | P | E | K | R | P | T | F | E | F | L | N | H | Y | F | E | S | F | S |
| Query Conservation |   |
  |   |   |   |
|   |   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|
|   |   |
|   |   |   |
|
|   |   |   |
| Alig confidence |   |
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  | . | . |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |
|
|   |   |   |
|   |   |
|   |
| Template Sequence |   |
T | . |
. |
S | V | E | A | M | Y | S | V | A | S | Q | C | L | H | E | K | K | N | K | R | P | D | I | K | K | V | Q | Q | L | L | Q | E | M | T |
| Template Known Secondary structure |   |
 | . | . |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S | T | T | T | S |
|
|  |  |  |  |  |  |  |  |  |  | T |
|
| Template Predicted Secondary structure |   |
 | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
424 | |
|
. | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . |
|   |