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Job DescriptionP00528
Confidence100.00%DateTue Jan 22 11:25:29 GMT 2013
Rank2Aligned Residues449
% Identity41%Templatec2fo0A_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
Resolution2.27 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   86...90.........100.........110.........120.........130.........140.........150.........160.....
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Query Sequence  TTPTGVPGVVLKRVVVALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFE
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Template Sequence  ENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ. TKNGQGWVPSNYITPVNSLEKHSWYHG
Template Known Secondary structure  TTTT

GGGS
TTSS
B


STTB

B
TT

TTSS.TTGGGTTSGGGSTT
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   71........80.........90.........100.........110.........120.. .......130.........140.........
 
   166...170.........180.........190.........200.........210.........220.........230.........240.....
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Query Sequence  NVLRKEADKLLLAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYS
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Template Sequence  PVSRNAAEYLLS. . SGINGSFLVRESESSPGQRSISLRY. . . . . EGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHS
Template Known Secondary structure 

TS..SS
TT
SSSTT
.....TT
TTS
SSTT

BSS
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   150.........160. ........170.........180...... ...190.........200.........210.........220..
 
   246...250.........260.........270.........280.........290.........300..... ....310.........320....
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Query Sequence  KNALGLCHILSRPCPKPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRN. SIDVAVKTLREGTMSTAAF
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Template Sequence  TVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEF
Template Known Secondary structure 

TTSSS











SSS
SSTT

B

GGGSGGGTTSSGGGT

TTS

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   223......230.........240.........250.........260.........270.........280.........290.........300..
 
   325....330.........340.........350.........360.........370.........380.........390.........400....
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Query Sequence  LQEAAIMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRD
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Template Sequence  LKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRN
Template Known Secondary structure 


TTB


SSSS


TT
BS
TTTS
TT
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   303......310.........320.........330.........340.........350.........360.........370.........380..
 
   405....410.........420.........430.........440.........450.........460.........470.........480....
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Query Sequence  LAARNVLIGENNVAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGM
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Template Sequence  LAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGI
Template Known Secondary structure 
SGGG
GGG


TT


SS



TT



GGG



TTS

SSTT
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   383......390.........400.........410.........420.........430.........440.........450.........460..
 
   485....490.........500.........510.........520.........530.........540....
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Query Sequence  HSREVIENIERGFRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESFSVTSE
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Template Sequence  DLSQVYELLEKDYRMERPEG. . CPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESS
Template Known Secondary structure 
TT





TT..

T
SSGGGS

TSSSSS
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   463......470.........480.. .......490.........500.........510.........520
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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