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Job DescriptionP00528
Confidence100.00%DateTue Jan 22 11:25:29 GMT 2013
Rank5Aligned Residues431
% Identity49%Templatec2c0iA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   97..100.........110.........120.........130.........140.........150.........160.........170......
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Query Sequence  KRVVVALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLL
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Template Sequence  RIIVVALYDYEAIHHEDLSFQKGDQMVVLEE. SGEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQL
Template Known Secondary structure 

SS
B


SSSB

B
TT
.TTTTT

GGGTTSGGGSTTTT

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   5960.........70.........80......... 90.........100.........110.........120.........130.......
 
   177..180.........190.........200.........210.........220.........230.........240.........250......
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Query Sequence  LAEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKNALGLCHILS
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Template Sequence  LAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLS
Template Known Secondary structure  TSTT

TT

SSSTT
TTTB

STT
SSTTSSSTTSS
SS
SS


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   138.140.........150.........160.........170.........180.........190.........200.........210.......
 
   257..260.........270.........280.........290.........300.........310.........320.........330......
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Query Sequence  RPCPKPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRH
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Template Sequence  VPCMSSKPQK. . . . PWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVEAFLAEANVMKTLQH
Template Known Secondary structure  SB







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TT
SB

GGGTTTTT


SS
T


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   218.220....... ..230.........240.........250.........260.........270.........280.........290...
 
   337..340.........350.........360.........370.........380.........390.........400.........410......
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Query Sequence  NRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENN
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Template Sequence  DKLVKLHAVV. TKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASL
Template Known Secondary structure  TTB

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SSS


TT
BSTTGGG

TT


S

SGGG
TT
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   294.....300... ......310.........320.........330.........340.........350.........360.........370..
 
   417..420.........430.........440.........450.........460.........470.........480.........490......
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Query Sequence  VAKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERG
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Template Conservation    
  




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Template Sequence  VCKIADFGLAR. . . . . . . . . . . . . VIPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERG
Template Known Secondary structure 


TTGGG.............T

GGGS




TTT

SSTT

TT
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   373......380... ......390.........400.........410.........420.........430.........
 
   497..500.........510.........520.........530.........540........
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Query Sequence  FRMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESFSVTSEVPYR
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Template Sequence  YRMPRPEN. . CPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQEE
Template Known Secondary structure 





TT..

T
SSGGGS

TTTS
GGG


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   453......460 .........470.........480.........490.........500..
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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