Return to main results Retrieve Phyre Job Id

Job DescriptionP00528
Confidence100.00%DateTue Jan 22 11:25:29 GMT 2013
Rank1Aligned Residues449
% Identity55%Templatec1y57A_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
Resolution1.91 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   98.100.........110.........120.........130.........140.........150.........160.........170.......
Predicted Secondary structure 

















































Query SS confidence 















































































Query Sequence  RVVVALYDYKSRDESDLSFMKGDRMEVIDDTESDWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLL
Query Conservation    




 
      

 
 


   

      

       
  
 

 


     

   



 


 


 

 
Alig confidence 















































































Template Conservation     

          

    

   
       

       
  
 

 
 
     
    

 
 
 
  

  
 
Template Sequence  TTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLL
Template Known Secondary structure  TSS
B


SSSB

B
TT

S

SSSSTTT

GGGTTSGGGSTTS

T
Template Predicted Secondary structure 
















































Template SS confidence 















































































   84.....90.........100.........110.........120.........130.........140.........150.........160...
 
   178.180.........190.........200.........210.........220.........230.........240.........250.......
Predicted Secondary structure 










































Query SS confidence 















































































Query Sequence  AEENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKNALGLCHILSR
Query Conservation        
 



 

   
 
 



         





     
 
 
     
 

 


  
    


   
  
Alig confidence 















































































Template Conservation        
 



 
    
   


          
 
  
     
         
 

  

  
      
   
  
Template Sequence  NAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTT
Template Known Secondary structure 
TT

TT

SSSTT
TTT
SSS
SSTTSSS

TTSSS



Template Predicted Secondary structure 













































Template SS confidence 















































































   164.....170.........180.........190.........200.........210.........220.........230.........240...
 
   258.260.........270.........280.........290.........300.........310.........320.........330.......
Predicted Secondary structure 





































Query SS confidence 















































































Query Sequence  PCPKPQPQMWDLGPELRDKYEIPRSEIQLLRKLGRGNFGEVFYGKWRNSIDVAVKTLREGTMSTAAFLQEAAIMKKFRHN
Query Conservation             
        

    
 
   

 
 

 
  
       



 

        

 
  

  
 

Alig confidence 












...































































Template Conservation               ...    

      
   

 
 

 
  
       



 
         
  
  

  
 

Template Sequence  VCPTSKPQTQGLA. . . KDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHE
Template Known Secondary structure  B







SS

...

TTB

GGGTTTTT
TTSS



T
Template Predicted Secondary structure 












...



























Template SS confidence 















































































   244.....250...... ...260.........270.........280.........290.........300.........310.........320
 
   338.340.........350.........360.........370.........380.........390.........400.........410.......
Predicted Secondary structure 

































Query SS confidence 















































































Query Sequence  RLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVASGMEYLESKQLIHRDLAARNVLIGENNV
Query Conservation 


 
 
         

 
    


   
       
          


 

 


   






  



     
Alig confidence 









.




































































Template Conservation 


 
 
   .     

 

   


   
                  
    
  
     

 

   
 
      
Template Sequence  KLVQLYAVVS. EEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLV
Template Known Secondary structure  TB


.SSS


TTS

TT
S

SGGG
GGG
Template Predicted Secondary structure 
.




































Template SS confidence 















































































   321........330 .........340.........350.........360.........370.........380.........390.........
 
   418.420.........430.........440.........450.........460.........470.........480.........490.......
Predicted Secondary structure 




































Query SS confidence 















































































Query Sequence  AKICDFGLARVIADDEYCPKQGSRFPVKWTAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGF
Query Conservation   

 




                 
 
 


 
     
 










 



 
  

      
    
  
 
Alig confidence 















































































Template Conservation   

 




                     


       
 








 
 

 
 
  
        
   
  
 
Template Sequence  CKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGY
Template Known Secondary structure 


TT


SS




TTTT
SGGGS




TTS

SSTT

TT
Template Predicted Secondary structure 




































Template SS confidence 















































































   400.........410.........420.........430.........440.........450.........460.........470.........
 
   498.500.........510.........520.........530.........540.........550..
Predicted Secondary structure 

























Query SS confidence 






















































Query Sequence  RMPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFEFLNHYFESFSVTSEVPYREVQD
Query Conservation 
   
     
  
  

  

  

  



  
   

         
 
  
Alig confidence 






..













































Template Conservation 
   
  ..    
  

  
   

  


   
   

         
     
Template Sequence  RMPCPPE. . CPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGEN
Template Known Secondary structure 




TT..

T
SSGGGS

TT
TT



S
Template Predicted Secondary structure 






..


















Template SS confidence 






















































   480...... ...490.........500.........510.........520.........530..
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions