Job Description P00528 Confidence 100.00% Date Tue Jan 22 11:25:29 GMT 2013 Rank 3 Aligned Residues 438 % Identity 41% Template c1oplA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase Resolution 3.42 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		97	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	R	V	V	V	A	L	Y	D	Y	K	S	R	D	E	S	D	L	S	F	M	K	G	D	R	M	E	V	I	D	D	T	E	S	D	W	W	R	V	V	N	L	T	T	R	Q	E	G	L	I	P	L	N	F	V	A	E	E	R	S	V	N	S	E	D	W	F	F	E	N	V	L	R	K	E	A	D	K	L	L
Query Conservation
Alig confidence																																											.
Template Conservation																																											.
Template Sequence		P	N	L	F	V	A	L	Y	D	F	V	A	S	G	D	N	T	L	S	I	T	K	G	E	K	L	R	V	L	G	Y	N	H	N	G	E	W	C	E	A	Q	.	T	K	N	G	Q	G	W	V	P	S	N	Y	I	T	P	V	N	S	L	E	K	H	S	W	Y	H	G	P	V	S	R	N	A	A	E	Y	L	L
Template Known Secondary structure		T	T					S	S		B				S	T	T	B			B		T	T										T	T	S	S						.		S	S							G	G	G				S	S	S	G	G	G	S	T	T														G
Template Predicted Secondary structure																																											.
Template SS confidence
		82	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.		.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160
		177	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	A	E	E	N	P	R	G	T	F	L	V	R	P	S	E	H	N	P	N	G	Y	S	L	S	V	K	D	W	E	D	G	R	G	Y	H	V	K	H	Y	R	I	K	P	L	D	N	G	G	Y	Y	I	A	T	N	Q	T	F	P	S	L	Q	A	L	V	M	A	Y	S	K	N	A	L	G	L	C	H	I	L	S
Query Conservation
Alig confidence			.	.																										.	.	.	.	.
Template Conservation			.	.																										.	.	.	.	.
Template Sequence		S	.	.	S	G	I	N	G	S	F	L	V	R	E	S	E	S	S	P	G	Q	R	S	I	S	L	R	Y	.	.	.	.	.	E	G	R	V	Y	H	Y	R	I	N	T	A	S	D	G	K	L	Y	V	S	S	E	S	R	F	N	T	L	A	E	L	V	H	H	H	S	T	V	A	D	G	L	I	T	T	L	H
Template Known Secondary structure		G	.	.	G			T	T								S	S	S	T	T									.	.	.	.	.	T	T											T	T	S				S	S	T	T	S		B	S	S									T	T			T	T	S	S	S
Template Predicted Secondary structure			.	.																										.	.	.	.	.
Template SS confidence
		161			.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.						.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.
		257	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.		.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.
Predicted Secondary structure																																																			.
Query SS confidence																																																			.
Query Sequence		R	P	C	P	K	P	Q	P	Q	M	W	D	L	G	P	E	L	R	D	K	Y	E	I	P	R	S	E	I	Q	L	L	R	K	L	G	R	G	N	F	G	E	V	F	Y	G	K	W	R	N	.	S	I	D	V	A	V	K	T	L	R	E	G	T	M	S	T	A	A	F	L	Q	E	A	A	I	M	K	K	F	R
Query Conservation																																																			.
Alig confidence																																																			.
Template Conservation
Template Sequence		Y	P	A	P	K	R	N	K	P	T	V	Y	G	V	S	P	N	Y	D	K	W	E	M	E	R	T	D	I	T	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	E	G	V	W	K	K	Y	S	L	T	V	A	V	K	T	L	K	E	D	T	M	E	V	E	E	F	L	K	E	A	A	V	M	K	E	I	K
Template Known Secondary structure								S					S	S	S		S	S	S	S			B			G	G	G							S	G	G	G	T	T	S	S							G	G	G	T										S	S	S	S
Template Predicted Secondary structure
Template SS confidence
		234	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.
		336	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	N	R	L	V	A	L	Y	A	V	C	S	Q	E	E	P	I	Y	I	V	Q	E	Y	M	S	K	G	S	L	L	D	F	L	R	E	G	D	G	R	Y	L	H	F	E	D	L	I	Y	I	A	T	Q	V	A	S	G	M	E	Y	L	E	S	K	Q	L	I	H	R	D	L	A	A	R	N	V	L	I	G	E	N
Query Conservation
Alig confidence
Template Conservation
Template Sequence		H	P	N	L	V	Q	L	L	G	V	C	T	R	E	P	P	F	Y	I	I	T	E	F	M	T	Y	G	N	L	L	D	Y	L	R	E	C	N	R	Q	E	V	N	A	V	V	L	L	Y	M	A	T	Q	I	S	S	A	M	E	Y	L	E	K	K	N	F	I	H	R	N	L	A	A	R	N	C	L	V	G	E	N
Template Known Secondary structure			T	T	B									S	S	S	S									T	T		B								S		T	T	T	S																						T	T				S			S	G	G	G					G	G
Template Predicted Secondary structure
Template SS confidence
		314	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.
		416	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	V	A	K	I	C	D	F	G	L	A	R	V	I	A	D	D	E	Y	C	P	K	Q	G	S	R	F	P	V	K	W	T	A	P	E	A	I	I	Y	G	K	F	S	I	K	S	D	V	W	S	Y	G	I	L	L	M	E	L	F	T	Y	G	Q	V	P	Y	P	G	M	H	S	R	E	V	I	E	N	I	E	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		H	L	V	K	V	A	D	F	G	L	S	R	L	M	T	G	D	T	Y	T	A	H	A	G	A	K	F	P	I	K	W	T	A	P	E	S	L	A	Y	N	K	F	S	I	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	S	P	Y	P	G	I	D	L	S	Q	V	Y	E	L	L	E	K
Template Known Secondary structure		G							T	T						T	T							T	T					G	G	G																													T	T	S			S	S	T	T			T	T	T							T
Template Predicted Secondary structure
Template SS confidence
		394	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.
		496	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	F	R	M	P	K	P	T	N	H	Y	F	P	D	N	I	Y	Q	L	L	L	Q	C	W	D	A	V	P	E	K	R	P	T	F	E	F	L	N	H	Y	F	E	S	F	S	V	T	S	E
Query Conservation
Alig confidence											.	.
Template Conservation											.	.
Template Sequence		D	Y	R	M	E	R	P	E	G	.	.	C	P	E	K	V	Y	E	L	M	R	A	C	W	Q	W	N	P	S	D	R	P	S	F	A	E	I	H	Q	A	F	E	T	M	F	Q	E	S	S
Template Known Secondary structure		T							T	T	.	.													T		S	S	G	G	G	S												T	S		S	S	S
Template Predicted Secondary structure											.	.
Template SS confidence
		474	.	.	.	.	.	480	.	.			.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520