Job Description P00528 Confidence 99.91% Date Tue Jan 22 11:25:29 GMT 2013 Rank 344 Aligned Residues 182 % Identity 28% Template c1a81E_ PDB info PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam Resolution 3.00 Å

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		7	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.			.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.
Predicted Secondary structure																														.	.
Query SS confidence																														.	.
Query Sequence		S	K	R	Q	D	Q	E	L	A	L	A	Y	P	T	G	G	Y	K	K	S	D	Y	T	F	G	Q	T	H	.	.	I	N	S	S	G	G	G	N	M	G	G	V	L	G	Q	K	H	N	N	G	G	S	L	D	S	R	Y	T	P	D	P	N	H	R	G	P	L	K	I	G	G	K	G	G	V	D	I	I	R	P
Query Conservation																														.	.
Alig confidence																					.	.	.	.	.	.	.	.		.	.
Template Conservation																					.	.	.	.	.	.	.	.
Template Sequence		S	R	N	Y	L	G	G	F	A	L	S	V	A	H	G	R	K	A	H	.	.	.	.	.	.	.	.	H	Y	T	I	E	R	E	L	N	G	T	Y	A	I	A	G	G	R	T	H	A	S	P	A	D	L	C	H	Y	H	S	Q	E	S	D	G	L	V	C	L	L	K	K	P	F	N	R	P	Q	G	V	Q	P
Template Known Secondary structure			S	S	S	T	T									S	S	S			.	.	.	.	.	.	.	.								T	T	T					T	T	S			B	S	S									T	T			T	T	S	S	S				S	B					T	T
Template Predicted Secondary structure																					.	.	.	.	.	.	.	.
Template SS confidence
		44	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.									.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.
		85	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	T	T	P	T	G	V	P	G	V	V	L	K	R	V	V	V	A	L	Y	D	Y	K	S	R	D	E	S	D	L	S	F	M	K	G	D	R	M	E	V	I	D	D	T	E	S	D	W	W	R	V	V	N	L	T	T	R	Q	E	G	L	I	P	L	N	F	V	A	E	E	R	S	V	N	S	E	D	W	F	F
Query Conservation
Alig confidence							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		K	T	P	Q	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	K	L	I	A	T	T	A	H	E	K	M	P	W	F	H
Template Known Secondary structure							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.							T	S	G	G	G		T	T
Template Predicted Secondary structure							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		116	.	.	.	120																																																												.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.
		165	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	N	V	L	R	K	E	A	D	K	L	L	L	A	E	E	N	P	R	G	T	F	L	V	R	P	S	E	H	N	P	N	G	Y	S	L	S	V	K	D	W	E	D	G	R	G	Y	H	V	K	H	Y	R	I	K	P	L	D	N	G	G	Y	Y	I	A	T	N	Q	T	F	P	S	L	Q	A	L	V	M	A	Y
Query Conservation
Alig confidence																													.													.	.	.	.	.
Template Conservation																													.													.	.	.	.	.
Template Sequence		G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	.	D	N	N	G	S	Y	A	L	C	L	L	H	.	.	.	.	.	E	G	K	V	L	H	Y	R	I	D	K	D	K	T	G	K	L	S	I	P	E	G	K	K	F	D	T	L	W	Q	L	V	E	H	Y
Template Known Secondary structure															S	S				T	T								.	S	S	S	S									.	.	.	.	.	T	T											T	T	S					T	T	S			B	S
Template Predicted Secondary structure																													.													.	.	.	.	.
Template SS confidence
		171	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.		.	.	200	.	.	.	.	.	.	.	.	.						210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.
		245	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	K	N	A	L	G	L	C	H	I	L	S	R	P	C	P	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	Y	K	A	D	G	L	L	R	V	L	T	V	P	C	Q	K
Template Known Secondary structure		T	T			T	T	S	S	S				S	B
Template Predicted Secondary structure
Template SS confidence
		245	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.

No model constructed - rank, confidence too low

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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