Phyre 2 Results for Q08012

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Email | l.a.kelley@imperial.ac.uk
Description | Q08012
Date | Wed Feb 13 11:17:06 GMT 2013
Unique Job ID | 314c60a0e4e9094e

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template c1griA_
Top template information
PDB header:signal transduction adaptor Chain: A: PDB Molecule:growth factor bound protein 2; PDBTitle: grb2
Confidence and coverage
Confidence: | 100.0% | Coverage: | 96%
203 residues ( 96% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | E | A | I | A | K | H | D | F | S | A | T | A | D | D | E | L | S | F | R | K | T | Q | I | L | K | I | L | N | M | E | D | D | S | N | W | Y | R | A | E | L | D | G | K | E | G | L | I | P | S | N | Y | I | E | M | K | N | H | D | W
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | Y | Y | G | R | I | T | R | A | D | A | E | K | L | L | S | N | K | H | E | G | A | F | L | I | R | I | S | E | S | S | P | G | D | F | S | L | S | V | K | C | P | D | G | V | Q | H | F | K | V | L | R | D | A | Q | S | K | F | F | L | W
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | V | V | K | F | N | S | L | N | E | L | V | E | Y | H | R | T | A | S | V | S | R | S | Q | D | V | K | L | R | D | M | I | P | E | E | M | L | V | Q | A | L | Y | D | F | V | P | Q | E | S | G | E | L | D | F | R | R | G | D | V | I | T
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  | ? | ? | ? | ? |  | ? | ? | ? | ? | ? |  | ? | ? |  | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | .
Sequence |  | V | T | D | R | S | D | E | N | W | W | N | G | E | I | G | N | R | K | G | I | F | P | A | T | Y | V | T | P | Y | H | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c1griA_ |

### PDB 1gri chain A

Region: 1 - 209
Aligned: 203
Modelled: 209
Confidence: 100.0%
Identity: 65%
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2

Phyre2
2 |
| c2lqnA_ |

### PDB 2lqn chain A

Region: 1 - 211
Aligned: 171
Modelled: 171
Confidence: 100.0%
Identity: 20%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl

Phyre2
3 |
| c2l3sA_ |

### PDB 2l3s chain A

Region: 3 - 209
Aligned: 158
Modelled: 158
Confidence: 100.0%
Identity: 22%
PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk

Phyre2
4 |
| c2eyzA_ |

### PDB 2eyz chain A

Region: 2 - 211
Aligned: 161
Modelled: 161
Confidence: 100.0%
Identity: 23%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii

Phyre2
5 |
| c1ng2A_ |

### PDB 1ng2 chain A

Region: 2 - 211
Aligned: 126
Modelled: 127
Confidence: 100.0%
Identity: 21%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox

Phyre2
6 |
| c1ov3A_ |

### PDB 1ov3 chain A

Region: 2 - 207
Aligned: 122
Modelled: 123
Confidence: 100.0%
Identity: 22%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex

Phyre2
7 |
| c2eyyA_ |

### PDB 2eyy chain A

Region: 50 - 211
Aligned: 162
Modelled: 162
Confidence: 99.9%
Identity: 28%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i

Phyre2
8 |
| c1k9aB_ |

### PDB 1k9a chain B

Region: 1 - 198
Aligned: 193
Modelled: 198
Confidence: 99.9%
Identity: 31%
PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution

Phyre2
9 |
| c2fo0A_ |

### PDB 2fo0 chain A

Region: 3 - 196
Aligned: 189
Modelled: 190
Confidence: 99.9%
Identity: 31%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase

Phyre2
10 |
| c1oplA_ |

### PDB 1opl chain A

Region: 3 - 188
Aligned: 181
Modelled: 186
Confidence: 99.9%
Identity: 31%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase

Phyre2
11 |
| c3qwyA_ |

### PDB 3qwy chain A

Region: 51 - 207
Aligned: 155
Modelled: 157
Confidence: 99.9%
Identity: 23%
PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2

Phyre2
12 |
| c2dvjA_ |

### PDB 2dvj chain A

Region: 50 - 210
Aligned: 161
Modelled: 161
Confidence: 99.9%
Identity: 32%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii

Phyre2
13 |
| c3qwxX_ |

### PDB 3qwx chain X

Region: 51 - 207
Aligned: 155
Modelled: 157
Confidence: 99.9%
Identity: 23%
PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174

Phyre2
14 |
| c1mv3A_ |

### PDB 1mv3 chain A

Region: 121 - 210
Aligned: 90
Modelled: 90
Confidence: 99.9%
Identity: 21%
PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc

Phyre2
15 |
| c2ablA_ |

### PDB 2abl chain A

Region: 3 - 150
Aligned: 148
Modelled: 148
Confidence: 99.9%
Identity: 34%
PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase

Phyre2
16 |
| d1ng2a2 |

### PDB 1ng2 chain A domain 2

Region: 141 - 209
Aligned: 69
Modelled: 69
Confidence: 99.8%
Identity: 16%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2
17 |
| c1y57A_ |

### PDB 1y57 chain A

Region: 3 - 196
Aligned: 189
Modelled: 194
Confidence: 99.8%
Identity: 28%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor

Phyre2
18 |
| c2c0iA_ |

### PDB 2c0i chain A

Region: 1 - 196
Aligned: 188
Modelled: 196
Confidence: 99.8%
Identity: 27%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983

Phyre2
19 |
| c2h8hA_ |

### PDB 2h8h chain A

Region: 3 - 175
Aligned: 173
Modelled: 173
Confidence: 99.8%
Identity: 30%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor

Phyre2
20 |
| c2dx1A_ |

### PDB 2dx1 chain A

Region: 152 - 211
Aligned: 60
Modelled: 60
Confidence: 99.8%
Identity: 35%
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c1griA_ |
|  | 100.0 | 65 | PDB header:signal transduction adaptor Chain: A: PDB Molecule:growth factor bound protein 2; PDBTitle: grb2
2 | c2lqnA_ |
|  | 100.0 | 20 | PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of crkl
3 | c2l3sA_ |
|  | 100.0 | 22 | PDB header:structural protein Chain: A: PDB Molecule:autoinhibited crk protein; PDBTitle: structure of the autoinhibited crk
4 | c2eyzA_ |
|  | 100.0 | 23 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform ii
5 | c1ng2A_ |
|  | 100.0 | 21 | PDB header:oxidoreductase activator Chain: A: PDB Molecule:neutrophil cytosolic factor 1; PDBTitle: structure of autoinhibited p47phox
6 | c1ov3A_ |
|  | 100.0 | 22 | PDB header:oxidoreductase activator Chain: A: PDB Molecule:neutrophil cytosol factor 1; PDBTitle: structure of the p22phox-p47phox complex
7 | c2eyyA_ |
|  | 99.9 | 28 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform i
8 | c1k9aB_ |
|  | 99.9 | 31 | PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
9 | c2fo0A_ |
|  | 99.9 | 31 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
10 | c1oplA_ |
|  | 99.9 | 31 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
11 | c3qwyA_ |
|  | 99.9 | 23 | PDB header:signaling protein Chain: A: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2
12 | c2dvjA_ |
|  | 99.9 | 32 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog, PDBTitle: phosphorylated crk-ii
13 | c3qwxX_ |
|  | 99.9 | 23 | PDB header:signaling protein Chain: X: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 1-174
14 | c1mv3A_ |
|  | 99.9 | 21 | PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:myc box dependent interacting protein 1; PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
15 | c2ablA_ |
|  | 99.9 | 34 | PDB header:transferase Chain: A: PDB Molecule:abl tyrosine kinase; PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
16 | d1ng2a2 |
|  | 99.8 | 16 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
17 | c1y57A_ |
|  | 99.8 | 28 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
18 | c2c0iA_ |
|  | 99.8 | 27 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983
19 | c2h8hA_ |
|  | 99.8 | 30 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor
20 | c2dx1A_ |
|  | 99.8 | 35 | PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crystal structure of rhogef protein asef
21 | c3nhnA_ |
| not modelled | 99.8 | 33 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
22 | c2dybA_ |
| not modelled | 99.8 | 22 | PDB header:oxidoreductase Chain: A: PDB Molecule:neutrophil cytosol factor 4; PDBTitle: the crystal structure of human p40(phox)
23 | c1x27F_ |
| not modelled | 99.8 | 34 | PDB header:signaling protein Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck; PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
24 | c2ed0A_ |
| not modelled | 99.8 | 27 | PDB header:signaling protein Chain: A: PDB Molecule:abl interactor 2; PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2)
25 | c4glmD_ |
| not modelled | 99.8 | 35 | PDB header:signaling protein Chain: D: PDB Molecule:dynamin-binding protein; PDBTitle: crystal structure of the sh3 domain of dnmbp protein [homo sapiens]
26 | c2df6A_ |
| not modelled | 99.8 | 38 | PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7; PDBTitle: crystal structure of the sh3 domain of betapix in complex2 with a high affinity peptide from pak2
27 | c3nmzD_ |
| not modelled | 99.8 | 29 | PDB header:cell adhesion/cell cycle Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4; PDBTitle: crytal structure of apc complexed with asef
28 | d1ov3a2 |
| not modelled | 99.8 | 16 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
29 | d1sema_ |
| not modelled | 99.8 | 63 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
30 | c2nwmA_ |
| not modelled | 99.8 | 34 | PDB header:cell adhesion Chain: A: PDB Molecule:vinexin; PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin
31 | d1utia_ |
| not modelled | 99.8 | 46 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
32 | d1oeba_ |
| not modelled | 99.8 | 44 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
33 | c2xmfA_ |
| not modelled | 99.8 | 30 | PDB header:motor protein Chain: A: PDB Molecule:myosin 1e sh3; PDBTitle: myosin 1e sh3
34 | c2cubA_ |
| not modelled | 99.8 | 22 | PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1
35 | c1g83A_ |
| not modelled | 99.8 | 33 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn; PDBTitle: crystal structure of fyn sh3-sh2
36 | c2dmoA_ |
| not modelled | 99.8 | 24 | PDB header:signaling protein Chain: A: PDB Molecule:neutrophil cytosol factor 2; PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2)
37 | c2yuoA_ |
| not modelled | 99.8 | 34 | PDB header:signaling protein Chain: A: PDB Molecule:run and tbc1 domain containing 3; PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3
38 | d1k4us_ |
| not modelled | 99.8 | 31 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
39 | c1zx6A_ |
| not modelled | 99.8 | 39 | PDB header:protein binding Chain: A: PDB Molecule:ypr154wp; PDBTitle: high-resolution crystal structure of yeast pin3 sh3 domain
40 | d1gcqa_ |
| not modelled | 99.8 | 60 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
41 | d1uuea_ |
| not modelled | 99.8 | 34 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
42 | d1pwta_ |
| not modelled | 99.8 | 33 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
43 | c2djqA_ |
| not modelled | 99.8 | 35 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:sh3 domain containing ring finger 2; PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2
44 | c2pqhA_ |
| not modelled | 99.8 | 33 | PDB header:structural protein Chain: A: PDB Molecule:spectrin alpha chain, brain; PDBTitle: structure of sh3 chimera with a type ii ligand linked to the chain c-2 terminal
45 | c1x2qA_ |
| not modelled | 99.8 | 38 | PDB header:signaling protein Chain: A: PDB Molecule:signal transducing adapter molecule 2; PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2
46 | c2drmB_ |
| not modelled | 99.8 | 38 | PDB header:contractile protein Chain: B: PDB Molecule:acanthamoeba myosin ib; PDBTitle: acanthamoeba myosin i sh3 domain bound to acan125
47 | d1gria2 |
| not modelled | 99.8 | 56 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
48 | c2yunA_ |
| not modelled | 99.8 | 32 | PDB header:protein transport Chain: A: PDB Molecule:nostrin; PDBTitle: solution structure of the sh3 domain of human nostrin
49 | c2dlpA_ |
| not modelled | 99.7 | 30 | PDB header:structural protein Chain: A: PDB Molecule:kiaa1783 protein; PDBTitle: solution structure of the sh3 domain of human kiaa17832 protein
50 | c2l0aA_ |
| not modelled | 99.7 | 43 | PDB header:signaling protein Chain: A: PDB Molecule:signal transducing adapter molecule 1; PDBTitle: solution nmr structure of signal transducing adapter molecule 1 stam-12 from homo sapiens, northeast structural genomics consortium target3 hr4479e
51 | c2bz8B_ |
| not modelled | 99.7 | 31 | PDB header:sh3 domain Chain: B: PDB Molecule:sh3-domain kinase binding protein 1; PDBTitle: n-terminal sh3 domain of cin85 bound to cbl-b peptide
52 | c2yt6A_ |
| not modelled | 99.7 | 23 | PDB header:cell cycle Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full- PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1
53 | d1wlpb2 |
| not modelled | 99.7 | 22 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
54 | c2dilA_ |
| not modelled | 99.7 | 27 | PDB header:cell adhesion Chain: A: PDB Molecule:proline-serine-threonine phosphatase-interacting PDBTitle: solution structure of the sh3 domain of the human proline-2 serine-threonine phosphatase-interacting protein 1
55 | d1u06a1 |
| not modelled | 99.7 | 35 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
56 | c2dl4A_ |
| not modelled | 99.7 | 43 | PDB header:signaling protein Chain: A: PDB Molecule:protein stac; PDBTitle: solution structure of the first sh3 domain of stac protein
57 | d1e6ga_ |
| not modelled | 99.7 | 31 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
58 | c2azsA_ |
| not modelled | 99.7 | 100 | PDB header:signaling protein Chain: A: PDB Molecule:sh2-sh3 adapter protein drk; PDBTitle: nmr structure of the n-terminal sh3 domain of drk2 (calculated without noe restraints)
59 | c1w70A_ |
| not modelled | 99.7 | 36 | PDB header:sh3 domain Chain: A: PDB Molecule:neutrophil cytosol factor 4; PDBTitle: sh3 domain of p40phox complexed with c-terminal polyproline2 region of p47phox
60 | c2dbkA_ |
| not modelled | 99.7 | 25 | PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structures of the sh3 domain of human crk-like2 protein
61 | c2dnuA_ |
| not modelled | 99.7 | 20 | PDB header:structural genomics, structural protein Chain: A: PDB Molecule:sh3 multiple domains 1; PDBTitle: solution structure of rsgi ruh-061, a sh3 domain from human
62 | c2lj0A_ |
| not modelled | 99.7 | 34 | PDB header:signaling protein Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1; PDBTitle: the third sh3 domain of r85fl
63 | c2dl3A_ |
| not modelled | 99.7 | 32 | PDB header:cell adhesion, signaling protein Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1; PDBTitle: solution structure of the first sh3 domain of human sorbin2 and sh3 domain-containing protein 1
64 | c1negA_ |
| not modelled | 99.7 | 33 | PDB header:structural protein Chain: A: PDB Molecule:spectrin alpha chain, brain; PDBTitle: crystal structure analysis of n-and c-terminal labeled sh3-2 domain of alpha-chicken spectrin
65 | d1nega_ |
| not modelled | 99.7 | 33 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
66 | c2ekhA_ |
| not modelled | 99.7 | 16 | PDB header:signaling protein Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a; PDBTitle: solution structures of the sh3 domain of human kiaa0418
67 | c2ebpA_ |
| not modelled | 99.7 | 23 | PDB header:cell adhesion Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1; PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1
68 | c2egeA_ |
| not modelled | 99.7 | 29 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein kiaa1666; PDBTitle: solution structure of the third sh3 domain from human2 kiaa1666 protein
69 | c2epdA_ |
| not modelled | 99.7 | 27 | PDB header:protein binding Chain: A: PDB Molecule:rho gtpase-activating protein 4; PDBTitle: solution structure of sh3 domain in rho-gtpase-activating2 protein 4
70 | c2oi3A_ |
| not modelled | 99.7 | 26 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)
71 | c2ysqA_ |
| not modelled | 99.7 | 36 | PDB header:signaling protein Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9; PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9
72 | c2kymA_ |
| not modelled | 99.7 | 25 | PDB header:signaling protein Chain: A: PDB Molecule:bud emergence protein 1; PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide
73 | d1udla_ |
| not modelled | 99.7 | 30 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
74 | d1ujya_ |
| not modelled | 99.7 | 29 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
75 | c1wi7A_ |
| not modelled | 99.7 | 25 | PDB header:protein binding Chain: A: PDB Molecule:sh3-domain kinase binding protein 1; PDBTitle: solution structure of the sh3 domain of sh3-domain kinase2 binding protein 1
76 | c2rqrA_ |
| not modelled | 99.7 | 18 | PDB header:protein binding Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
77 | c2eyxA_ |
| not modelled | 99.7 | 21 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: c-terminal sh3 domain of ct10-regulated kinase
78 | c1zlmA_ |
| not modelled | 99.7 | 42 | PDB header:signaling protein Chain: A: PDB Molecule:osteoclast stimulating factor 1; PDBTitle: crystal structure of the sh3 domain of human osteoclast2 stimulating factor
79 | c2ct3A_ |
| not modelled | 99.7 | 30 | PDB header:signaling protein Chain: A: PDB Molecule:vinexin; PDBTitle: solution structure of the sh3 domain of the vinexin protein
80 | c2dl8A_ |
| not modelled | 99.7 | 23 | PDB header:signaling protein Chain: A: PDB Molecule:slit-robo rho gtpase-activating protein 2; PDBTitle: solution structure of the sh3 domain of human slit-robo rho2 gtpase-activating protein 2
81 | c2ed1A_ |
| not modelled | 99.7 | 34 | PDB header:signaling protein Chain: A: PDB Molecule:130 kda phosphatidylinositol 4,5-biphosphate- PDBTitle: solution structure of the sh3 domain of 130 kda2 phosphatidylinositol 4,5-biphosphate-dependent arf1 gtpase-3 activating protein
82 | d1e6ha_ |
| not modelled | 99.7 | 29 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
83 | d1uj0a_ |
| not modelled | 99.7 | 51 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
84 | c4esrB_ |
| not modelled | 99.7 | 42 | PDB header:protein binding Chain: B: PDB Molecule:jouberin; PDBTitle: molecular and structural characterization of the sh3 domain of ahi-12 in regulation of cellular resistance of bcr-abl+ chronic myeloid3 leukemia cells to tyrosine kinase inhibitors
85 | c1x43A_ |
| not modelled | 99.7 | 33 | PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:sh3 domain grb2-like protein b1; PDBTitle: solution structure of the sh3 domain of endophilin b12 (sh3g1b1)
86 | c2dbmA_ |
| not modelled | 99.7 | 40 | PDB header:transferase, signaling protein Chain: A: PDB Molecule:sh3-containing grb2-like protein 2; PDBTitle: solution structures of the sh3 domain of human sh3-2 containing grb2-like protein 2
87 | d1h8ka_ |
| not modelled | 99.7 | 30 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
88 | c2d1xD_ |
| not modelled | 99.7 | 36 | PDB header:cell invasion Chain: D: PDB Molecule:cortactin isoform a; PDBTitle: the crystal structure of the cortactin-sh3 domain and amap1-2 peptide complex
89 | d1ue9a_ |
| not modelled | 99.7 | 25 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
90 | c1x2pA_ |
| not modelled | 99.7 | 24 | PDB header:transferase Chain: A: PDB Molecule:protein arginine n-methyltransferase 2; PDBTitle: solution structure of the sh3 domain of the protein2 arginine n-methyltransferase 2
91 | c2k2mA_ |
| not modelled | 99.7 | 28 | PDB header:signaling protein Chain: A: PDB Molecule:eps8-like protein 1; PDBTitle: structural basis of pxxdy motif recognition in sh3 binding
92 | d1ycsb2 |
| not modelled | 99.7 | 32 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
93 | c2csqA_ |
| not modelled | 99.7 | 26 | PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:rim binding protein 2; PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2
94 | c2fpeB_ |
| not modelled | 99.7 | 26 | PDB header:signaling protein Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein PDBTitle: conserved dimerization of the ib1 src-homology 3 domain
95 | c2cudA_ |
| not modelled | 99.7 | 19 | PDB header:signaling protein Chain: A: PDB Molecule:src-like-adapter; PDBTitle: solution structure of the sh3 domain of the human src-like2 adopter protein (slap)
96 | c1x69A_ |
| not modelled | 99.7 | 32 | PDB header:signaling protein Chain: A: PDB Molecule:cortactin isoform a; PDBTitle: solution structures of the sh3 domain of human src2 substrate cortactin
97 | c2egaA_ |
| not modelled | 99.7 | 23 | PDB header:signaling protein Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a; PDBTitle: solution structure of the first sh3 domain from human2 kiaa0418 protein
98 | c2jxbA_ |
| not modelled | 99.7 | 22 | PDB header:signaling protein complex Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain, PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex
99 | c2dl7A_ |
| not modelled | 99.7 | 33 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:kiaa0769 protein; PDBTitle: solution structure of the second sh3 domain of human2 kiaa0769 protein
100 | c2o2oA_ |
| not modelled | 99.7 | 24 | PDB header:protein binding Chain: A: PDB Molecule:sh3-domain kinase-binding protein 1; PDBTitle: solution structure of domain b from human cin85 protein
101 | d1oota_ |
| not modelled | 99.7 | 51 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
102 | c2krnA_ |
| not modelled | 99.7 | 36 | PDB header:signaling protein Chain: A: PDB Molecule:cd2-associated protein; PDBTitle: high resolution structure of the second sh3 domain of cd2ap
103 | c1wyxA_ |
| not modelled | 99.7 | 34 | PDB header:cell adhesion Chain: A: PDB Molecule:crk-associated substrate; PDBTitle: the crystal structure of the p130cas sh3 domain at 1.1 a2 resolution
104 | c1x6gA_ |
| not modelled | 99.7 | 19 | PDB header:signaling protein Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase; PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase.
105 | c2i0nA_ |
| not modelled | 99.7 | 27 | PDB header:structural protein Chain: A: PDB Molecule:class vii unconventional myosin; PDBTitle: structure of dictyostelium discoideum myosin vii sh3 domain2 with adjacent proline rich region
106 | d1uhfa_ |
| not modelled | 99.7 | 41 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
107 | c2rf0D_ |
| not modelled | 99.7 | 39 | PDB header:transferase Chain: D: PDB Molecule:mitogen-activated protein kinase kinase kinase 10; PDBTitle: crystal structure of human mixed lineage kinase map3k10 sh3 domain
108 | c2egcA_ |
| not modelled | 99.7 | 20 | PDB header:signaling protein Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a; PDBTitle: solution structure of the fifth sh3 domain from human2 kiaa0418 protein
109 | d1uhca_ |
| not modelled | 99.7 | 20 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
110 | c2yupA_ |
| not modelled | 99.7 | 35 | PDB header:cell adhesion Chain: A: PDB Molecule:vinexin; PDBTitle: solution structure of the second sh3 domain of human vinexin
111 | d1ov3a1 |
| not modelled | 99.7 | 22 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
112 | c1x6bA_ |
| not modelled | 99.7 | 21 | PDB header:signaling protein Chain: A: PDB Molecule:rho guanine exchange factor (gef) 16; PDBTitle: solution structures of the sh3 domain of human rho guanine2 exchange factor (gef) 16
113 | c1zukA_ |
| not modelled | 99.7 | 28 | PDB header:contractile protein Chain: A: PDB Molecule:myosin tail region-interacting protein mti1; PDBTitle: yeast bbc1 sh3 domain complexed with a peptide from las17
114 | c2js0A_ |
| not modelled | 99.7 | 24 | PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: solution structure of second sh3 domain of adaptor nck
115 | d1gbra_ |
| not modelled | 99.7 | 66 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
116 | d1ng2a1 |
| not modelled | 99.7 | 25 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
117 | c2j06B_ |
| not modelled | 99.7 | 18 | PDB header:signal transduction Chain: B: PDB Molecule:ras gtpase-activating protein 1; PDBTitle: crystal structure of the rasgap sh3 domain at 1.8 angstrom2 resolution
118 | c3cqtA_ |
| not modelled | 99.7 | 27 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn; PDBTitle: n53i v55l mutant of fyn sh3 domain
119 | c2eqiA_ |
| not modelled | 99.7 | 32 | PDB header:immune system, hydrolase Chain: A: PDB Molecule:phospholipase c, gamma 2; PDBTitle: solution structure of the sh3 domain from phospholipase c,2 gamma 2
120 | c2cucA_ |
| not modelled | 99.7 | 29 | PDB header:signaling protein Chain: A: PDB Molecule:sh3 domain containing ring finger 2; PDBTitle: solution structure of the sh3 domain of the mouse2 hypothetical protein sh3rf2

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Transmembrane helix prediction |

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