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Job DescriptionQ9VXH3
Confidence100.00%DateWed Feb 13 11:23:55 GMT 2013
Rank1Aligned Residues690
% Identity38%Templatec3ohmB_
PDB info PDB header:signaling protein / hydrolaseChain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase PDBTitle: crystal structure of activated g alpha q bound to its effector2 phospholipase c beta 3
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   18.20.........30.........40.........50.........60.........70.........80.........90.......
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Query Sequence  TIGMLERGTIVTKLYGKQRRPDRRHLMLIRETRQLLWATVATQTPRTDYEGAIQLREIREIRVGKHSKEFRLFADDCQRF
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Template Sequence  VVETLRRGSKFIKWDEETSSRNLVTLRVDPNGFFLYWTGPNMEVD. . . . . . TLDISSIRDTRTGRYARLPKDP. . KIREV
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TT

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TTS

GGG
......GGGTTTS



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   18.20.........30.........40.........50.........60.. .......70.........80.... .....
 
   98.100.........110. ........120.........130.........140.........150.........160.........170......
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Query Sequence  ESSKCFVILHGNHF. KLKSFSVVALSEIEADNWVRGLRYMVKDTLGAPYPLQIDRWLRREYYQIENVNTHSAKATEQSPA
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Template Sequence  LEEKLMTVVSGPDPVNTVFLNFMAVQDDTAKVWSEELFKLAMNILAQNAS. . RNTFLRKAYTKLK. . . . . . . . LQVNQDG
Template Known Secondary structure 

TT
SSGGG
SSSS
T

..........S

TTS
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   99100.........110.........120.........130.........140........ .150.........160. .......
 
   177..180........ .190.........200..... ....210.........220.........230.........240.........250...
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Query Sequence  QVTIKDFKLFLA. . GVSCKMTTGKFMEHFTE. DVRRKHDLKFDDFSRLYQKLLLPNGFASVLSGSGVANFPYSEDQQVVR
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Template Sequence  RIPVKNILKMFSADKKRVETALESCGLKFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIG. . . . . . AKGKPYLT
Template Known Secondary structure 
TTGGGTTT


STT

GGG

S

TT......

STT
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   169170.........180.........190.........200.........210.........220.........230.... .....240..
 
   254.....260.........270... ......280.........290.........300.........310.........320........
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Query Sequence  PAELKQFLETEQRDVSASEI. . . . . SSAAIASFIRDFVQDVERDVQEPYLTFPEFVDFLFSKQNDLWNSKYDQVFMDMNL
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Template Sequence  LEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKY. EPNQQFLERDQMSMEGFSRYLGGEENGILPLEALDLSTDMTQ
Template Known Secondary structure  SS
TTS
TTTS



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TT
TSTTS
SS
SS
S


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   243......250.........260.........270......... 280.........290.........300.........310.........320.
 
   329330.........340.........350.........360.........370..... ....380.........390.........400......
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Query Sequence  PLSSYWIASSHNTYLTGDQFSSESSCEAYARALRMGCRCIELDCWNG. . PDNLPYIFHGHTITSKIKFMDVIKTIKDHAF
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Template Sequence  PLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAF
Template Known Secondary structure 
GGG

BSSTTBSS
SS
B
STT




SSS



STTS

TT
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   322.......330.........340.........350.........360.........370.........380.........390.........400.
 
   407..410.........420. ........430.........440........ .450.........460.........470.........480.
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Query Sequence  TSSEYPVILSIEQNC. SLEQQRNMAQALIEVFGDMLLTQPCDR. . . . NEQHLPSPYQLRRKIILKHKKLPQFDDIANGIS
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Template Sequence  KTSPYPVILSFENHVDSAKQQAKMAEYCRSIFGDALLIEPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHTDEGTAS. . .
Template Known Secondary structure  SS

S



TTGGGB

S
BTTB
SSSS




TTTTTT






TTGGGT...
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   402.......410.........420.........430.........440.........450.........460.........470........
 
   482.......490.........500.........510.........520.........530.........540.........550.........560.
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Query Sequence  STGSLGHRSSLGGAGGGAHGENDGENVRKVFKEGLLYFKDPVDKSWNLYQFVLTHQELIYSSEINESRNGNSEDDDFGLS
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   562.......570.........580.........590.........600.........610.........620.........630.........640.
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Query Sequence  SSCSLNSNMQQKQKDTSANDELHFGENWFHGKLEGGRKEADDLLKKYKHFGDGTFLVRESATFVGDYSLSFWRRNRPNHC
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   642.......650.........660.........670.........680.........690.........700.........710.........720.
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Query Sequence  RIKLKHENGSIKYYLVENFVFDSLYSLIVYYRKNMLRSSEFSIILKEPVPQPKKHEDQEWFHPNTTKEQAEQGLYRLEIG
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   722.......730.........740.........750.........760.........770.........780.........790.........800.
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Query Sequence  SFLVRPSVQSINAFVISFTINRKIKHCRIMQEGRLYGIDTMNFESLVSLINYYTRNPLYRNVKLSHPVSQELLRQALAEA
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   802.......810.........820.........830.........840.........850.........860.........870.........880.
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Query Sequence  AQGDHSGGHDDNGASNYMGSNLEENVTCKALYSYKANKPDELSFPKHAIITNVQRDNSMWWIGDYGGMIKKHLPANYVKV
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   882.......890.........900.........910.........920.........930.........940.........950.........960.
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Query Sequence  IDSTTEDYNSLNEEGTDGRTDSIEIFGAVASLFESNDPGIIFKLQIQTPTMQNPFVIGFDNQETAYEWIKAIQEAALIAS
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   962.......970.........980.........990... ......1000.........1010.........1020.........1030......
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Query Sequence  QLASERRKKERTARVAKEMSDLIIYFRSVPFR. . . . . EHSWIFQEMSSFPETKAEKQFFQQNTQLFLSYHRNQISRVYPK
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Template Sequence  . . . . . . . . . . SEVNATEEMSTLVNYIEPVKFKSFEAARKRNKCFEMSSFVETKAMEQL. TKSPMEFVEYNKQQLSRIYPK
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TT
SS





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   582.......590.........600.........610.........620......... 630.........640.........650
 
   1037..1040.........1050.........1060.........1070.........1080.........1090..... ....1100.. .......1110...
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Query Sequence  GQRLDSSNFNPMPFWNVGSQMIALNYQTGDKAMQLNQAKFRNNGQCGYILKPSFMKSDS. . FNPNNPL. CDGLSEVKVSI
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Template Sequence  GTRVDSSNYMPQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIVDGIVANALRV
Template Known Secondary structure  TT
TT




TTTT
S
B
TT

STTGGG
S

GGGT
TT



TT
SS

TT


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   651........660.........670.........680.........690.........700.........710.........720.........730
 
   1114.....1120.........1130.........1140...... ...1150.........1160... ... ...1170.........1180.........1190
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Query Sequence  RLIAARHLFRGGKSNNPQIVVELIGASFDTGVK. YRTKVNENGFNPVWNES. CEF. NVRNPQFAILRFEVQDEDMFAETH
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Template Sequence  KVISGQFLSDRK. . VGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEG. . . . GK
Template Known Secondary structure  S

SS
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SSTTT
B







SS
SSS
B




S
GGG
TT....T
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   731........740.. .......750.........760.........770.........780.........790.........800.. ..
 
   1191........1200.........1210.........1220.........1230..
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Query Sequence  FIAQACYPLTCIRQGYRSVILRNKFSEELELSSLLINIKIAN
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Template Sequence  FVGHRILPVSAIRSGYHYVCLRNEANQPLCLPALLIYTEASD
Template Known Secondary structure  TTT



TTS
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   805....810.........820.........830.........840......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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