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Job DescriptionQ9VXH3
Confidence100.00%DateWed Feb 13 11:23:55 GMT 2013
Rank3Aligned Residues669
% Identity36%Templatec2fjuB_
PDB info PDB header:signaling protein,apoptosis/hydrolaseChain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate PDBTitle: activated rac1 bound to its effector phospholipase c beta 2
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   10.........20.........30.........40.........50.........60.........70.........80.........
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Query Sequence  PLLGEMEQTIGMLERGTIVTKLYGKQRRPDRRHLMLIRETRQLLWATVATQTPRTDYEGAIQLREIREIRVGKHSKEFRL
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Template Sequence  PKVK. . . . . . AYLSQGERFIKWDDETTVASPVILRVDPKGYYLYWTYQSKEME. . . . . . FLDITSIRDTRFGKFAKMPKS
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SSSSS

TTS
TTS
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S
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   11... .....20.........30.........40.........50....... ..60.........70........
 
   90. ........100.........110. ........120.........130.........140.........150.........160.
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Query Sequence  FA. . . . . . . DDCQRFESSKCFVILHGNHF. KLKSFSVVALSEIEADNWVRGLRYMVKDTLGAPYPLQIDRWLRREYYQIE
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Template Sequence  QKLRDVFNMDFPDNSFLLKTLTVVSGPDMVDLTFHNFVSYKENVGKAWAEDVLALVKHPLTANASRS. . TFLDKILVKLK
Template Known Secondary structure  TTTTSTT

GGGT
SSSSS
SSSST
T

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   7980.........90.........100.........110.........120.........130.........140..... ....150......
 
   162.......170.........180.........190. ........200..... ....210.........220.........230........
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Query Sequence  NVNTHSAKATEQSPAQVTIKDFKLFLAGVS. . CKMTTGKFMEHFTE. DVRRKHDLKFDDFSRLYQKLLLPNGFASVLSGS
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Template Conservation   ........     
 
  
 
  
       
      
     
 
      
 
 

  
   
  
 

  
    
Template Sequence  M. . . . . . . . QLNSEGKIPVKNFFQMFPADRKRVEAALSACHLPKGKNDAINPEDFPEPVYKSFLMSLCPRPEIDEIFTSY
Template Known Secondary structure  ........S

TTS
STT
TT


SSS

GGGS
TTS



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   157 ..160.........170.........180.........190.........200.........210.........220........
 
   239240.........250.........260.........270.........280.........290.........300.........310........
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Query Sequence  GVANFPYSEDQQVVRPAELKQFLETEQRDVSASEISSAAIASFIRDFVQDVERDVQEPYLTFPEFVDFLFSKQNDLWNSK
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Template Conservation  ............. 
      

   
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Template Sequence  . . . . . . . . . . . . . MTKEHLTKFINQKQRDQ. . . . . . . . . . . GLIDKY. EPS. . . . . . GQLSPEGMVWFLCGPENSVLAQD
Template Known Secondary structure  .............
BTS


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B

STTS
SB
GG
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   236...240.........250.. ...... .260. ........270.........280....
 
   319320.........330.........340.........350.........360.........370..... ....380.........390......
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Query Sequence  YDQVFMDMNLPLSSYWIASSHNTYLTGDQFSSESSCEAYARALRMGCRCIELDCWNG. . PDNLPYIFHGHTITSKIKFMD
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Template Sequence  KLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKE
Template Known Secondary structure  GGSS
S


S
GGG
BBSSTTBSS
SSSS
B
TTT




TTTT



TTSS


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   307..310.........320.........330.........340.........350.........360.........370.........380......
 
   397..400.........410.........420. ........430.........440........ .450.........460.........470.
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Query Sequence  VIKTIKDHAFTSSEYPVILSIEQNC. SLEQQRNMAQALIEVFGDMLLTQPCDR. . . . NEQHLPSPYQLRRKIILKHKKLP
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Template Conservation 

  
   

  
 







 

 
  

  

  
    

 
   
           



  

 




 
   
Template Sequence  AIEAIAESAFKTSPYPIILSFENHVDSPRQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKEE
Template Known Secondary structure  TTTS

S




GGGB

S

TTS
SSTT




TTTTTT





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   387..390.........400.........410.........420.........430.........440.........450.........460......
 
   472.......480.........490.........500.........510.........520.........530.........540.........550.
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Query Sequence  QFDDIANGISSTGSLGHRSSLGGAGGGAHGENDGENVRKVFKEGLLYFKDPVDKSWNLYQFVLTHQELIYSSEINESRNG
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Template Conservation             .....................................................................
Template Sequence  SGNLDEEEIKK. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure 




TTTTTT.....................................................................
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   514.....520....
 
   552.......560.........570.........580.........590.........600.........610.........620.........630.
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Query Sequence  NSEDDDFGLSSSCSLNSNMQQKQKDTSANDELHFGENWFHGKLEGGRKEADDLLKKYKHFGDGTFLVRESATFVGDYSLS
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Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ................................................................................
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   632.......640.........650.........660.........670.........680.........690.........700.........710.
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Query Sequence  FWRRNRPNHCRIKLKHENGSIKYYLVENFVFDSLYSLIVYYRKNMLRSSEFSIILKEPVPQPKKHEDQEWFHPNTTKEQA
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Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   712.......720.........730.........740.........750.........760.........770.........780.........790.
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Query Sequence  EQGLYRLEIGSFLVRPSVQSINAFVISFTINRKIKHCRIMQEGRLYGIDTMNFESLVSLINYYTRNPLYRNVKLSHPVSQ
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   792.......800.........810.........820.........830.........840.........850.........860.........870.
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Query Sequence  ELLRQALAEAAQGDHSGGHDDNGASNYMGSNLEENVTCKALYSYKANKPDELSFPKHAIITNVQRDNSMWWIGDYGGMIK
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Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   872.......880.........890.........900.........910.........920.........930.........940.........950.
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Query Sequence  KHLPANYVKVIDSTTEDYNSLNEEGTDGRTDSIEIFGAVASLFESNDPGIIFKLQIQTPTMQNPFVIGFDNQETAYEWIK
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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   952.......960.........970.........980.........990... ......1000.........1010.........1020......
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Query Sequence  AIQEAALIASQLASERRKKERTARVAKEMSDLIIYFRSVPFR. . . . . EHSWIFQEMSSFPETKAEKQFFQQNTQLFLSYH
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Template Sequence  . . . . . . . . . . . MQSDEGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRSYVISSFTELKAYDLL. SKASVQFVDYN
Template Known Secondary structure  ...........TTTTTGGGG





TT
SS





T
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   525....530.........540.........550.........560.........570.........580. ........590..
 
   1027..1030.........1040.........1050.........1060.........1070.........1080.........1090.........1100......
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Query Sequence  RNQISRVYPKGQRLDSSNFNPMPFWNVGSQMIALNYQTGDKAMQLNQAKFRNNGQCGYILKPSFMKSDSFNPNNPLCDGL
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Template Sequence  KRQMSRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHEFMRR. . . . . . . . . . . . .
Template Known Secondary structure  S

TT
TT





TT


B
TT

STTTGGG
S

GGGT
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   593......600.........610.........620.........630.........640.........650.........
 
   1107..1110.........1120.........1130.........1140...... ...1150.........1160. ...... ..1170.........1180..
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Query Sequence  SEVKVSIRLIAARHLFRGGKSNNPQIVVELIGASFDTGVK. . YRTKVNENGFNPVWN. ESCEFN. VRNPQFAILRFEVQD
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Template Sequence  . PTTLSITVISGQFLSER. . SVRTYVEVELFGLPGDPKRRYRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVME
Template Known Secondary structure  .

S

SS..




TTS







SSS

SS
B







S
GGG
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   660.........670...... ...680.........690.........700.........710.........720.........730......
 
   1183......1190.........1200.........1210.........1220.........1230..
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Query Sequence  EDMFAETHFIAQACYPLTCIRQGYRSVILRNKFSEELELSSLLINIKIAN
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Template Sequence  EG. . . . NKFLGHRIIPINALNSGYHHLCLHSESNMPLTMPALFIFLEMKD
Template Known Secondary structure  TT....TGGGB


TT


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   754. ....760.........770.........780.........790.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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