Job Description Q9VXH3 Confidence 99.86% Date Wed Feb 13 11:23:55 GMT 2013 Rank 23 Aligned Residues 198 % Identity 25% Template c1a81E_ PDB info PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam Resolution 3.00 Å

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		586	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	E	N	W	F	H	G	K	L	E	G	G	R	K	E	A	D	D	L	L	K	K	Y	K	H	F	G	D	G	T	F	L	V	R	E	S	A	T	F	V	G	D	Y	S	L	S	F	W	R	R	N	R	P	N	H	C	R	I	K	L	K	H	E	N	G	S	I	K	Y	Y	L	V	E	N	F	V	F	D	S	L
Query Conservation
Alig confidence												.	.												.																																									.	.	.
Template Conservation												.	.												.																																									.	.	.
Template Sequence		H	L	P	F	F	F	G	N	I	T	.	.	R	E	E	A	E	D	Y	L	V	Q	G	.	G	M	S	D	G	L	Y	L	L	R	Q	S	R	N	Y	L	G	G	F	A	L	S	V	A	H	G	R	K	A	H	H	Y	T	I	E	R	E	L	N	G	.	.	.	T	Y	A	I	A	G	G	R	T	H	A	S	P
Template Known Secondary structure		G		T	T			S	S			.	.										T	T	.	T			T	T								S	S	S	T	T									S	S	S										T	T	T	.	.	.					T	T	S			B	S	S
Template Predicted Secondary structure												.	.												.																																									.	.	.
Template SS confidence
		12	.	.	.	.	.	.	.	20	.			.	.	.	.	.	.	.	.	30	.	.		.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.				.	.	.	.	.	.	.	80	.	.	.	.	.
		666	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.														.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.			.	.	.	.	720	.	.	.	.	.	.	.	.	.	730
Predicted Secondary structure																														.	.	.	.	.	.	.	.	.	.	.	.	.																							.	.
Query SS confidence																														.	.	.	.	.	.	.	.	.	.	.	.	.																							.	.
Query Sequence		Y	S	L	I	V	Y	Y	R	K	N	M	L	R	S	S	E	F	S	I	I	L	K	E	P	V	P	Q	P	.	.	.	.	.	.	.	.	.	.	.	.	.	K	K	H	E	D	Q	E	W	F	H	P	N	T	T	K	E	Q	A	E	Q	G	L	.	.	Y	R	L	E	I	G	S	F	L	V	R	P	S	V	Q
Query Conservation																														.	.	.	.	.	.	.	.	.	.	.	.	.																							.	.
Alig confidence																														.	.	.	.	.	.	.	.	.	.	.	.	.																							.	.														.
Template Conservation																																																																																.
Template Sequence		A	D	L	C	H	Y	H	S	Q	E	S	D	G	L	V	C	L	L	K	K	P	F	N	R	P	Q	G	V	Q	P	K	T	P	Q	L	E	K	L	I	A	T	T	A	H	E	K	M	P	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	.	D
Template Known Secondary structure									T	T			T	T	S	S	S				S	B					T	T															T	S	G	G	G		T	T																S	S				T	T								.	S
Template Predicted Secondary structure																																																																																.
Template SS confidence
		86	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.		.
		731	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750			.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790
Predicted Secondary structure																						.	.
Query SS confidence																						.	.
Query Sequence		S	I	N	A	F	V	I	S	F	T	I	N	R	K	I	K	H	C	R	I	.	.	M	Q	E	G	R	L	Y	G	I	D	T	M	N	F	E	S	L	V	S	L	I	N	Y	Y	T	R	N	P	L	Y	R	N	V	K	L	S	H	P	V	S
Query Conservation																						.	.
Alig confidence																						.	.
Template Conservation
Template Sequence		N	N	G	S	Y	A	L	C	L	L	H	E	G	K	V	L	H	Y	R	I	D	K	D	K	T	G	K	L	S	I	P	E	G	K	K	F	D	T	L	W	Q	L	V	E	H	Y	S	Y	K	A	D	G	L	L	R	V	L	T	V	P	C	Q
Template Known Secondary structure		S	S	S									T	T											T	T	S					T	T	S			B	S										T	T			T	T	S	S	S				S	B
Template Predicted Secondary structure
Template SS confidence
		199	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions