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Job DescriptionQ7KSQ2
Confidence100.00%DateTue Jan 22 11:45:00 GMT 2013
Rank7Aligned Residues365
% Identity39%Templatec4fl2A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch
Resolution2.19 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   350.........360......... 370.........380.........390.........400...... ...410.........420......
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Query Sequence  LNAMPWFHGSITRDEAEHLL. . QPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKY. LENKLTIDDEEYFENLGQLV
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Template Sequence  HEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARD. NNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLV
Template Known Secondary structure  GGGSTTB

S

SSS

TT
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TTS
STT


BSS
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   163......170.........180.........190........ .200.........210.........220.........230.........240.
 
   427..430.........440.........450...... ...460.........470...... ...480.........490.
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Query Sequence  AHYEADADGLCTQLIKCLPKLGKQEFCINS. . . . . . . . . . . . KDFVDKGWVIPEAELQLRES. IGKGEFGDVMLGILR. .
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Template Sequence  EHYSYKADGLLRVLTVPCQKIGTQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMK
Template Known Secondary structure  TTB
TTSSS


SB


S


TT

GGGSGGGS
GGGSTTS


SSSB

GGGTTT
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   242.......250.........260.........270.........280.........290.........300.........310.........320.
 
   492.......500. ........510.........520.........530.........540.........550.........560.....
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Query Sequence  . . NEKVAVKMLK. . . . DEGAVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKD
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Template Sequence  KVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGIC. EAESWMLVMEMAELGPLNKYLQQNRH. . VKDKN
Template Known Secondary structure  T
SGGG
GGG


TTB

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TT
B
TT..S
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   394.....400.........410.........420.........430......... 440.........450.........460..... ....470
 
   566...570.........580.........590.........600.........610....... ..620.........630.........
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Query Sequence  QIIFAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAREECYN. . . . . . LDVGKLPIKWTAPEALKNGRFS
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Template Sequence  IIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFS
Template Known Secondary structure  TT


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SGGGTT

TTTT

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BTTB
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   471........480.........490.........500.........510.........520.........530.........540.........550
 
   640.........650.........660.........670.........680.........690.........700.........710........
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Query Sequence  NKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQLL
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Template Sequence  SKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY
Template Known Secondary structure  TTT

SSTT

TT





TT

T
SSTTTS

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   551........560.........570.........580.........590.........600.........610.........620.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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