Return to main results Retrieve Phyre Job Id

Job DescriptionQ7KSQ2
Confidence100.00%DateTue Jan 22 11:45:00 GMT 2013
Rank5Aligned Residues361
% Identity43%Templatec2h8hA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   350.........360.........370.. .......380.........390........ .400...... ...410.........420.
Predicted Secondary structure 













..



















.....







.












Query SS confidence 






















. .

























. . . . .







.














Query Sequence  LNAMPWFHGSITRDEAEHLLQPR. . EDGLFLVRESTNFPGDYTLCVCFQSK. . . . . VEHYRVKY. LENKLTIDDEEYFEN
Query Conservation                     
   ..                          .....        .               
Alig confidence 






















..

























.....







.














Template Conservation 
    

 
 
 
  

  
       
 



 
    
 
 


          
 
  
     
         
 
Template Sequence  IQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNS
Template Known Secondary structure  GGGSTTB

S

T
TT

TT
SSSTT
TTTB
.

S
TTSS
Template Predicted Secondary structure 












































Template SS confidence 















































































   143......150.........160.........170.........180.........190.........200.........210.........220..
 
   422.......430.........440.........450.........460.........470.........480.........490.. .......500
Predicted Secondary structure 







































.
Query SS confidence 






































































.







Query Sequence  LGQLVAHYEADADGLCTQLIKCLPKLGKQEFCINSKDFVDKGWVIPEAELQLRESIGKGEFGDVMLGILRN. EKVAVKML
Query Conservation                                              
          

 
  
 
       .   
 
  
Alig confidence 


























.....






































.







Template Conservation 
 


  
      
   
        .....            
          

 
 

 
          



  
Template Sequence  LQQLVAYYSKHADGLCHRLTTVCPTSK. . . . . PQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTL
Template Known Secondary structure 

TTSSS







.....


SSSSTT
SB

GGG
SSTTT
Template Predicted Secondary structure 


















.....
























Template SS confidence 















































































   223......230.........240......... 250.........260.........270.........280.........290.......
 
   501 ........510.........520.........530.........540.........550.........560.........570.........
Predicted Secondary structure 
.






















Query SS confidence 
.













































































Query Sequence  K. DEGAVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQIIFAYDTASGMEY
Query Conservation   .          
      
 
  

              
 
    
 
   
                       
  
Alig confidence 
.






























.













































Template Conservation           
  
  

  
 




 
 
   .     




   


   
                   
   
  
Template Sequence  KPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVS. EEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAY
Template Known Secondary structure 
TTSS



TTB


.SSS



TTSTT

Template Predicted Secondary structure 










.















Template SS confidence 















































































   298.300.........310.........320.........330 .........340.........350.........360.........370......
 
   580.........590.........600.........610....... ..620.........630.........640.........650.....
Predicted Secondary structure 
























....













Query SS confidence 





































. . . .





































Query Sequence  LEAKKVVHRDLAARNVLISEDCVAKVSDFGLAREECYN. . . . LDVGKLPIKWTAPEALKNGRFSNKSDMWSFGILLWEIY
Query Conservation 

   
 
 


  


       

 


        ....         
 


           
  
 
    
  
Alig confidence 





































....





































Template Conservation 

     
 

   


       

 




                     


       
 








 
 

 
Template Sequence  VERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELT
Template Known Secondary structure  TT


S

SGGG
GGG


TTSTTT


TT
STTS
GGGS




T
Template Predicted Secondary structure 








































Template SS confidence 















































































   377..380.........390.........400.........410.........420.........430.........440.........450......
 
   656...660.........670.........680.........690.........700.........710......
Predicted Secondary structure 


























Query SS confidence 




























































Query Sequence  SFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQ
Query Conservation    
  
                                        
  

        
 
Alig confidence 




























































Template Conservation 
 
  

           
  
     
   
  
  

  

   
  


   
   
 
Template Sequence  TKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLE
Template Known Secondary structure  TTT

SSTT

TT





TT

T
SSGGGS

Template Predicted Secondary structure 




























Template SS confidence 




























































   457..460.........470.........480.........490.........500.........510.......
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions