|   |   |
469 | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | |
|
. | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
| . | . |
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | E | L | Q | L | R | E | S | I | G | K | G | E | F | G | D | V | M | L | G | I | L | R | . |
. |
N | E | K | V | A | V | K | M | L | K | D | E | G | A | V | Q | K | F | L | A | E | A | S | V | M | T | T | L | E | H | D | N | L | V | K | F | I | G | L | V | F | T | S | K | H | L | Y | L | V | T | E | Y | M | S | K |
| Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |
|   |   |   |   |   |   | . | . |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
| Template Sequence |   |
E | D | W | D | L | V | Q | T | L | G | E | G | A | Y | G | E | V | Q | L | A | V | N | R | V | T | E | E | A | V | A | V | K | I | V | D | M | K | R | C | P | E | N | I | K | K | E | I | C | I | N | K | M | L | N | H | E | N | V | V | K | F | Y | G | H | R | R | E | G | N | I | Q | Y | L | F | L | E | Y | C | S | G |
| Template Known Secondary structure |   |
| S |  |  |  |  |  |  |
|
|
|
| S | S |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | B |
|
|  |  |  |  |  |
| S | T | T |  |  |  |  |  |  |
|
|
| T | T |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
7 | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . |
|   |
|   |   |
547 | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 620 | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | S | L | V | D | Y | L | R | S | R | G | R | Q | H | I | T | K | K | D | Q | I | I | F | A | Y | D | T | A | S | G | M | E | Y | L | E | A | K | K | V | V | H | R | D | L | A | A | R | N | V | L | I | S | E | D | C | V | A | K | V | S | D | F | G | L | A | R | . |
. |
. |
. |
. |
E | E | C | Y | N | L | D | V | G |
| Query Conservation |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |
|   |
|
|
|   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
G | E | L | F | D | R | I | E | P | D | I | G | . |
. |
M | P | E | P | D | A | Q | R | F | F | H | Q | L | M | A | G | V | V | Y | L | H | G | I | G | I | T | H | R | D | I | K | P | E | N | L | L | L | D | E | R | D | N | L | K | I | S | D | F | G | L | A | T | V | F | R | Y | N | N | R | E | R | L | L | N | K | M |
| Template Known Secondary structure |   |
 |  | G | G | G | G | S | B | T | T | T | B | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
| S | G | G | G |  |  |  |
| T | T |
|
|  |  |  |
|
|
| T | T |
|  |  |
|  |  | T | T |  |  |
|
| B |
| S |
|
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
90 | . | . | . | . | . | . | . | . | . | 100 | . | |
|
. | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . |
|   |
|   |   |
622 | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | |
. | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | |
|
. | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | L | P | I | K | W | T | A | P | E | A | L | K | N | G | R | . |
F | S | N | K | S | D | M | W | S | F | G | I | L | L | W | E | I | Y | S | F | G | R | V | P | Y | P | R | I | P | L | A | D | V | V | K | H | V | E | V | . |
. |
G | Y | K | M | E | A | P | E | G | C | P | P | E | I | Y | E | M | M | R | Q | A | W |
| Query Conservation |   |
  |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   | . |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|
|
|
|   |   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |
|
| Template Sequence |   |
C | G | T | L | P | Y | V | A | P | E | L | L | K | R | R | E | F | H | A | E | P | V | D | V | W | S | C | G | I | V | L | T | A | M | L | A | . |
G | E | L | P | W | D | Q | P | S | D | S | C | Q | E | Y | S | D | W | K | E | K | K | T | Y | L | N | P | W | K | K | I | D | S | A | P | L | A | L | L | H | K | I | L |
| Template Known Secondary structure |   |
| S |
| G | G | G | S |
|  |  |  |  |  |
| S | S | B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S |
| S | S |
|
| T | T |
|  |  |  |  |  |  |  | T | T |
| T | T | S | T | T | G | G | G | T |
|  |  |  |  |  |  |  |  |  |  | S |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
168 | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | |
. | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . |
|   |
|   |   |
699 | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | L | N | P | A | K | R | P | T | F | A | E | L | K | V |
| Query Conservation |   |
  |   |   |
|   |   |
|
|   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|
|   |   |
|   |
|   |   |
|
|
|   |
| Template Sequence |   |
V | E | N | P | S | A | R | I | T | I | P | D | I | K | K |
| Template Known Secondary structure |   |
| S | S | T | T | T | S |
|
|  |  |  |  | T | T |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
247 | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . |
|   |