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Job DescriptionQ9VGK8
Confidence100.00%DateWed Feb 13 11:19:23 GMT 2013
Rank7Aligned Residues363
% Identity40%Templatec4fl2A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch
Resolution2.19 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   434.....440.........450. ........460.........470.........480......... 490.........500.........510
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Query Sequence  AMPWFHGSITRDEAEHLL. . QPREDGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYL. ENKLTIDDEEYFENLGQLVAH
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Template Sequence  KMPWFHGKISREESEQIVLIGSKTNGKFLIRARD. NNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEH
Template Known Secondary structure  GSTTB

S

SSS

TT
.TTTTT
TTS
STT


BSS
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   165....170.........180.........190........ .200.........210.........220.........230.........240...
 
   511........520.........530........ .540.........550........ .560.........570...
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Query Sequence  YEADADGLCTQLIKCLPKLGKQEFCINS. . . . . . . . . . . . KDFVDKGWVIPEAELQLRES. IGKGEFGDVMLGILR. . . .
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Template Sequence  YSYKADGLLRVLTVPCQKIGTQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKV
Template Known Secondary structure  TTB
TTSSS


SB


S


TT

GGGSGGGS
GGGSTTS


SSSB

GGGTTTT
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   244.....250.........260.........270.........280.........290.........300.........310.........320...
 
   574.....580... ......590.........600.........610.........620.........630.........640.........
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Query Sequence  NEKVAVKMLK. . . . DEGAVQKFLAEASVMTTLEHDNLVKFIGLVFTSKHLYLVTEYMSKGSLVDYLRSRGRQHITKKDQI
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Template Sequence  VKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGIC. EAESWMLVMEMAELGPLNKYLQQNRH. . VKDKNII
Template Known Secondary structure 
SGGG
GGG


TTB

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TT
B
TT..S
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   396...400.........410.........420.........430......... 440.........450.........460..... ....470..
 
   650.........660.........670.........680.........690........ .700.........710.........720...
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Query Sequence  IFAYDTASGMEYLEAKKVVHRDLAARNVLISEDCVAKVSDFGLAREECY. . . . . . NLDVGKLPIKWTAPEALKNGRFSNK
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Template Sequence  ELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSK
Template Known Secondary structure  TT


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SGGGTT

TTTT

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   473......480.........490.........500.........510.........520.........530.........540.........550..
 
   724.....730.........740.........750.........760.........770.........780.........790.........800
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Query Sequence  SDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWDLNPAKRPTFAELKVKLQLL
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Template Sequence  SDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY
Template Known Secondary structure  TTT

SSTT

TT





TT

T
SSTTTS

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   553......560.........570.........580.........590.........600.........610.........620.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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