Job Description Q9VGK8 Confidence 100.00% Date Wed Feb 13 11:19:23 GMT 2013 Rank 74 Aligned Residues 239 % Identity 28% Template c3vw6B_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor Resolution 2.40 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		545	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.			.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.
Predicted Secondary structure																															.	.
Query SS confidence																															.	.
Query Sequence		G	W	V	I	P	E	A	E	L	Q	L	R	E	S	I	G	K	G	E	F	G	D	V	M	L	G	I	L	R	.	.	N	E	K	V	A	V	K	M	L	K	D	E	G	A	V	Q	K	F	L	A	E	A	S	V	M	T	T	L	E	H	D	N	L	V	K	F	I	G	L	V	F	T	S	K	H	L	Y	L	V
Query Conservation																															.	.
Alig confidence																															.	.												.	.	.	.
Template Conservation																																												.	.	.	.
Template Sequence		E	Y	D	Y	E	Y	D	E	N	G	D	R	V	V	L	G	K	G	T	Y	G	I	V	Y	A	G	R	D	L	S	N	Q	V	R	I	A	I	K	E	I	P	E	.	.	.	.	Q	P	L	H	E	E	I	A	L	H	K	H	L	K	H	K	N	I	V	Q	Y	L	G	S	F	S	E	N	G	F	I	K	I	F
Template Known Secondary structure							B		T	T	S	S	B							S	S	S								T	T	T												.	.	.	.											T	T				T	T	B										T	T
Template Predicted Secondary structure																																												.	.	.	.
Template SS confidence
		672	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.					.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.
		623	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.		.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.		680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Predicted Secondary structure																					.																																							.
Query SS confidence																					.																																							.
Query Sequence		T	E	Y	M	S	K	G	S	L	V	D	Y	L	R	S	R	G	R	Q	.	H	I	T	K	K	D	Q	I	I	F	A	Y	D	T	A	S	G	M	E	Y	L	E	A	K	K	V	V	H	R	D	L	A	A	R	N	V	L	I	.	S	E	D	C	V	A	K	V	S	D	F	G	L	A	R	E	E	C	Y	N	L
Query Conservation																					.																																							.
Alig confidence																					.																																							.																.	.	.	.	.	.
Template Conservation																																																																												.	.	.	.	.	.
Template Sequence		M	E	Q	V	P	G	G	S	L	S	A	L	L	R	S	K	W	G	P	L	K	D	N	E	Q	T	I	G	F	Y	T	K	Q	I	L	E	G	L	K	Y	L	H	D	N	Q	I	V	H	R	D	I	K	G	D	N	V	L	I	N	T	Y	S	G	V	L	K	I	S	D	F	G	T	S	K	.	.	.	.	.	.
Template Known Secondary structure						T	T		B								T	T				T	T																						T	T				S			S	G	G	G					T	T	T									S	S			.	.	.	.	.	.
Template Predicted Secondary structure																																																																												.	.	.	.	.	.
Template SS confidence
		754	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.
		701	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.			720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.			.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.
Predicted Secondary structure																					.	.																														.	.
Query SS confidence																					.	.																														.	.
Query Sequence		D	V	G	K	L	P	I	K	W	T	A	P	E	A	L	K	N	G	R	.	.	F	S	N	K	S	D	M	W	S	F	G	I	L	L	W	E	I	Y	S	F	G	R	V	P	Y	P	R	I	P	.	.	L	A	D	V	V	K	H	V	E	V	G	Y	K	M	E	A	P	E	G	C	P	P	E	I	Y	E	M	M
Query Conservation																					.	.																														.	.
Alig confidence		.																			.	.																				.										.	.
Template Conservation		.																																								.
Template Sequence		.	R	L	T	G	T	L	Q	Y	M	A	P	E	I	I	D	K	G	P	R	G	Y	G	K	A	A	D	I	W	S	L	G	C	T	I	I	E	M	A	T	.	G	K	P	P	F	Y	E	L	G	E	P	Q	A	A	M	F	K	V	G	M	F	K	V	H	P	E	I	P	E	S	M	S	A	E	A	K	A	F	I
Template Known Secondary structure		.						G	G	G										G	G	G		S																		.	S	S		T	T	G	G	G		S												T							T	T	S
Template Predicted Secondary structure		.																																								.
Template SS confidence
			828	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.		.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.
		777	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	Q	A	W	D	L	N	P	A	K	R	P	T	F	A	E	L	K	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	K	C	F	E	P	D	P	D	K	R	A	C	A	N	D	L	L	V
Template Known Secondary structure					T		S		T	T	T	S								T
Template Predicted Secondary structure
Template SS confidence
		916	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions