|   |   |
546 | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | |
. | . | . | . | . | 570 | . | . | . | |
|
. | . | . | . | . | . | 580 | . | . | . | |
|
. | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 |
| Predicted Secondary structure |   |
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |  |  |
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
W | V | I | P | E | A | E | L | Q | L | R | E | S | I | G | K | G | E | F | . |
G | D | V | M | L | G | I | L | R | . |
. |
N | E | K | V | A | V | K | M | L | K | . |
. |
D | E | G | A | V | Q | K | F | L | A | E | A | S | V | M | T | T | L | E | H | D | N | L | V | K | F | I | G | L | V | F | T | S | K | H | L | Y |
| Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
| . |
|   |
|   |   |   |   |   |   | . | . |   |   |   |   |
|   |
|   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
| Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   | . | . |   |   |
| Template Sequence |   |
Q | H | I | K | R | R | D | I | V | L | K | R | E | L | G | F | K | V | F | L | A | E | C | Y | N | L | S | P | T | K | D | K | M | L | V | A | V | K | A | L | K | D | P | T | L | A | A | R | K | D | F | Q | R | E | A | E | L | L | T | N | L | Q | H | E | H | I | V | K | F | Y | G | V | C | G | D | P | . |
. |
L | I |
| Template Known Secondary structure |   |
|  |  |
| G | G | G |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | S |
|
| S | S | S | S |  |  |  |  |  |  |  |  |
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | B |
|
|  |  |  |  |  |
|
|
| . | . |
|  |
| Template Predicted Secondary structure |   |
 |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
| . | . |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
531 | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | |
|
. | . |
|   |
|   |   |
621 | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | V | T | E | Y | M | S | K | G | S | L | V | D | Y | L | R | S | R | G | R | Q | H | I | T | K | K | D | Q | I | I | F | A | Y | D | T | A | S | G | M | E | Y | L | E | A | K | K | V | V | H | R | D | L | A | A | R | N | V | L | I | S | E | D | C | V | A | K | V | S | D | F | G | L | A | R | E | E | C | Y | N | L |
| Query Conservation |   |
  |
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |
|
|
|   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| Template Conservation |   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |
| Template Sequence |   |
M | V | F | E | Y | M | K | H | G | D | L | N | K | F | L | R | A | H | G | P | . |
E | L | G | L | S | Q | M | L | H | I | A | S | Q | I | A | S | G | M | V | Y | L | A | S | Q | H | F | V | H | R | D | L | A | T | R | N | C | L | V | G | A | N | L | L | V | K | I | G | D | F | G | M | D | . |
V | Y | S | T | D | Y |
| Template Known Secondary structure |   |
 |  |  |  |
|
| T | T |  |  |  |  |  |  |  |  | T | T |
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| S |
|
| S | G | G | G |  |  |  |
| G | G | G |
|  |  |  |
|
|
|
|
|
| . |
| S | G | G | G |
|
| Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  | . |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
615 | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | |
. | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | |
. | . | . | 690 | . | . |
|   |
|   |   |
701 | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 |
| Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | V | G | K | L | P | I | K | W | T | A | P | E | A | L | K | N | G | R | F | S | N | K | S | D | M | W | S | F | G | I | L | L | W | E | I | Y | S | F | G | R | V | P | Y | P | R | I | P | L | A | D | V | V | K | H | V | E | V | G | Y | K | M | E | A | P | E | G | C | P | P | E | I | Y | E | M | M | R | Q | A | W |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|
| Template Sequence |   |
Y | R | T | M | L | P | I | R | W | M | P | P | E | S | I | M | Y | R | K | F | T | T | E | S | D | V | W | S | F | G | V | I | L | W | E | I | F | T | Y | G | K | Q | P | W | F | Q | L | S | N | T | E | V | I | E | C | I | T | Q | G | R | V | L | E | R | P | R | V | C | P | K | E | V | Y | D | V | M | L | G | C | W |
| Template Known Secondary structure |   |
B |
|
|
| B |
| G | G | G |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | S |
|
| T | T | T | T | S |
|  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |
|
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
781 | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | L | N | P | A | K | R | P | T | F | A | E | L | K | V | K | L | Q | L | L | N | N | A | T |
| Query Conservation |   |
  |   |   |
|   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|   |   |
|
|
|   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |
| Template Sequence |   |
Q | R | E | P | Q | Q | R | L | N | I | K | E | I | Y | K | I | L | H | A | L | G | K | A | T |
| Template Known Secondary structure |   |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| Template Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
808 | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . |
|   |