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Job DescriptionQ9V9J3
Confidence100.00%DateTue Jan 22 11:49:10 GMT 2013
Rank7Aligned Residues373
% Identity40%Templatec4fl2A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch
Resolution2.19 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   126...130.........140.........150.........160.........170.........180.........190.........200.....
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Query Sequence  EAEPWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRDGDTVKHYRIRQLDEGGFFIARRTTFRTLQELVE
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Template Sequence  EKMPWFHGKISREESEQIVLIGSKTNGKFLIRARD. NNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVE
Template Known Secondary structure  GGSTTB

S

SSS

TT
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TTS
STT


BSS
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   164.....170.........180.........190........ .200.........210.........220.........230.........240..
 
   206...210.........220........ .230.........240.........250... ......260.........270
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Query Sequence  HYSKDSDGLCVNLCKPCVQIEKP. . . . . . VTEGLSHRTRDQWEIDRTSLKFVRK. . . . . . . . LGSGQFGDVWEGLWNNT.
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Template Sequence  HYSYKADGLLRVLTVPCQKIGTQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKK
Template Known Secondary structure  TTB
TTSSS


SB


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TT

GGGSGGGS
GGGSTTS


SSSB

GGGTTTT
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   243......250.........260.........270.........280.........290.........300.........310.........320..
 
   271........280. ........290.........300.........310.........320.........330.........340.....
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Query Sequence  . . TPVAIKTLKSG. . . TMDPKDFLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQ
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Template Sequence  VVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGIC. EAESWMLVMEMAELGPLNKYLQ. . . . QNRHVKDK
Template Known Secondary structure 
SGGG
GGG


TTB

.SSS

TT
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   395....400.........410.........420.........430......... 440.........450.........460. ........
 
   346...350.........360.........370.........380.........390......... 400.........410.........420...
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Query Sequence  TLIDMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDE. . YEARVGARFPIKWTAPEAANYSKF
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Template Sequence  NIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKF
Template Known Secondary structure  TT


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SGGGTT

TTTT

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BTTB
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   470.........480.........490.........500.........510.........520.........530.........540.........
 
   424.....430.........440.........450.........460.........470.........480.........490.........500...
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Query Sequence  SIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETLQWKLEDF
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Template Sequence  SSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY
Template Known Secondary structure 
TTT

SSTT

TT





TT

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   550.........560.........570.........580.........590.........600.........610.........620.........
 
   504
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Query Sequence  Y
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Template Conservation   
Template Sequence  Y
Template Known Secondary structure 
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   630
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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