|   |   |
246 | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | |
. | 270 | . | . | . | . | . | . | . | . | . | |
|
|
|
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | |
. | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
T | S | L | K | F | V | R | K | L | G | S | G | Q | F | G | D | V | W | E | G | L | W | N | . |
N | T | T | P | V | A | I | K | T | L | K | . |
. |
. |
. |
S | G | T | M | D | P | K | D | F | L | A | E | A | Q | I | M | K | K | . |
L | R | H | T | K | L | I | Q | L | Y | A | V | C | T | V | E | E | P | I | Y | I | I |
| Query Conservation |   |
  |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . |   |   |   |   |
|
|
|
|   |
|   | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   | . |
|   |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |
|   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
| Template Sequence |   |
E | D | F | I | L | H | K | M | L | G | K | G | S | F | G | K | V | F | L | A | E | F | K | K | T | N | Q | F | F | A | I | K | A | L | K | K | D | V | V | L | M | D | D | D | V | E | C | T | M | V | E | K | R | V | L | S | L | A | W | E | H | P | F | L | T | H | M | F | C | T | F | Q | T | K | E | N | L | F | F | V |
| Template Known Secondary structure |   |
T | T |  |  |  |  |  |  |  |  |  |
| S | S | S |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| T | T | B |
|
|  |  |  |  |  |  |
| S | S |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
378 | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . |
|   |
|   |   |
320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
T | E | L | M | K | H | G | S | L | L | E | Y | L | Q | A | I | A | G | K | G | R | S | L | K | M | Q | T | L | I | D | M | A | A | Q | I | A | A | G | M | A | Y | L | E | S | Q | N | Y | I | H | R | D | L | A | A | R | N | V | L | V | G | D | G | N | I | V | K | I | A | D | F | G | L | A | R | L | I | K | E | D | E |
| Query Conservation |   |
  |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|   |
|
|
|   |   |   |   |
|
|   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
M | E | Y | L | N | G | G | D | L | M | Y | H | I | Q | S | C | H | K | . |
. |
. |
. |
F | D | L | S | R | A | T | F | Y | A | A | E | I | I | L | G | L | Q | F | L | H | S | K | G | I | V | Y | R | D | L | K | L | D | N | I | L | L | D | K | D | G | H | I | K | I | A | D | F | G | M | C | K | E | N | M | L | G | D |
| Template Known Secondary structure |   |
 |  |
|
| T | T |
| B |  |  |  |  |  |  |  |  | S | S | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| B |
|
|
|
|
| G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
|
| T | T |
| B |
|
|
|
| T | T |
| Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
| . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
458 | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | |
|
|
|
. | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . |
|   |
|   |   |
400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | E | A | R | V | G | A | R | F | P | I | K | W | T | A | P | E | A | A | N | Y | S | K | F | S | I | K | S | D | V | W | S | F | G | I | L | L | T | E | L | V | T | Y | G | R | I | P | Y | P | G | M | T | N | A | E | V | L | T | Q | V | E | H | G | Y | R | M | P | Q | P | P | N | C | E | P | R | L | Y | E | I | M |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   | . | . |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |
|
|
|
|   |   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|
| Template Sequence |   |
A | K | T | N | F | C | G | T | P | . |
. |
D | Y | I | A | P | E | I | L | L | G | Q | K | Y | N | H | S | V | D | W | W | S | F | G | V | L | L | Y | E | M | L | I | . |
G | Q | S | P | F | H | G | Q | D | E | E | E | L | F | H | S | I | R | M | D | . |
N | P | F | Y | P | R | W | L | E | K | E | A | K | D | L | L |
| Template Known Secondary structure |   |
|
| B |
|
|
| S |
| G | . | . | G | G |
|
|  |  |  |  | T | T |
|
| B |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
|
| S | S |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
| T | T | S |
|  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
534 | . | . | . | . | . | 540 | . | . | |
|
. | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | |
. | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | |
. | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | |
. | . | . | . | . | |
|
|
|
|
|
|
. | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |
|
|
|  | . |  |  |  |  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | E | C | W | H | K | D | P | M | R | R | P | T | F | . |
E | T | L | Q | W | . |
. |
. |
. |
. |
. |
. |
K | L | E | D | F | Y | T | S | D | Q | S | D | Y | K | E | A | Q | A | Y |
| Query Conservation |   |
  |   |
|   |   |   |
|
|   |   |
|
|
|   | . |   |   |
|   |   | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|   |   |
|
|   |   |
|   |
|   |   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
| Template Sequence |   |
V | K | L | F | V | R | E | P | E | K | R | L | G | V | R | G | D | I | R | Q | H | P | L | F | R | E | I | N | W | E | E | L | E | R | K | E | I | D | P | Q | N | M | F | R | N | F |
| Template Known Secondary structure |   |
 |  |  | S |
| S | S | G | G | G | S | B | T | T | B | S |
| G | G | G | S | G | G | G | T | T |
|
|  |  |  |  |  | T | T |
| S |
|
|
|
| T | T | T | T |
|
| Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
611 | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . |
|   |