Phyre 2 Results for Q9VPU1

Phyre Home | Retrieve Phyre Job Id

Email | l.a.kelley@imperial.ac.uk
Description | Q9VPU1
Date | Tue Jan 22 11:34:19 GMT 2013
Unique Job ID | 1e0757b109763eb9

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template c2fo0A_
Top template information
PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
Confidence and coverage
Confidence: | 100.0% | Coverage: | 32%
174 residues ( 32% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
342 residues ( 62%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | L | E | H | P | Q | R | F | V | R | N | I | P | D | S | S | A | S | S | Q | Q | Y | P | Q | Q | Q | Q | H | P | P | Q | L | P | Q | H | Q | N | L | N | L | N | Q | N | Q | N | L | N | Q | N | Q | I | Y | Q | Y | R | P | Q | V | P | V
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | P | V | P | G | S | P | A | H | H | Q | R | H | S | S | L | S | Q | Q | Q | Q | L | H | H | H | R | T | L | S | T | A | S | S | C | S | A | Q | H | K | S | V | T | F | G | Q | P | A | L | D | C | G | G | N | G | S | G | S | A | N | G | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | G | S | G | N | S | S | S | G | S | A | A | G | N | A | G | T | Q | S | M | A | G | N | M | K | H | G | K | S | Q | D | D | V | C | Y | V | V | A | K | Y | D | Y | A | A | Q | G | A | Q | E | L | D | L | R | K | N | E | R | Y | L | L | L
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? |  | ? |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240
Sequence |  | D | D | S | K | H | W | W | R | V | Q | N | S | R | N | Q | S | G | Y | V | P | S | N | Y | V | K | K | E | K | P | S | L | F | D | S | I | K | K | K | V | K | K | G | S | G | S | K | T | L | P | N | C | S | P | S | R | Q | V | E | S | P
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? |  |  | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300
Sequence |  | T | M | S | R | R | L | P | P | D | P | A | E | A | I | G | T | A | V | V | K | Y | N | Y | Q | A | Q | Q | P | D | E | L | S | L | T | K | G | T | R | I | L | I | L | E | K | S | N | D | G | W | W | R | G | Q | S | G | N | S | V | G | W
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  | ? |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360
Sequence |  | F | P | S | N | Y | T | T | E | D | C | D | N | D | G | E | I | H | T | Y | A | M | A | E | N | V | L | D | I | V | V | A | L | Y | S | F | T | S | N | N | D | Q | E | L | S | F | E | K | G | D | R | L | E | I | V | D | R | P | A | S | D
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420
Sequence |  | P | D | W | Y | K | A | R | N | N | Q | G | Q | V | G | L | V | P | R | N | Y | L | Q | E | L | N | D | Y | L | A | T | P | Y | R | N | A | S | A | S | A | G | N | G | N | G | G | G | S | N | G | G | A | G | G | G | G | G | N | D | S | M
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  | ? | ? |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480
Sequence |  | E | R | R | N | E | G | N | K | P | A | A | Q | S | S | G | Q | P | I | E | R | P | N | L | A | G | K | S | W | Y | Y | G | A | I | T | R | S | Q | C | D | T | V | L | N | G | H | G | H | D | G | D | F | L | I | R | D | S | E | T | N | M
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540
Sequence |  | G | D | Y | S | V | S | L | K | A | P | G | R | N | K | H | F | R | V | H | V | E | Q | N | M | Y | C | I | G | Q | R | K | F | H | S | L | D | Q | L | V | D | H | Y | Q | R | A | P | I | Y | T | N | K | Q | G | E | K | L | Y | L | V | R
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? |  | ? |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | .
Sequence |  | S | L | P | K | A | N | G | T
Secondary structure |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |
Disorder |  |  |  | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c2fo0A_ |

### PDB 2fo0 chain A

Region: 299 - 548
Aligned: 174
Modelled: 194
Confidence: 100.0%
Identity: 36%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase

Phyre2
2 |
| c1k9aB_ |

### PDB 1k9a chain B

Region: 320 - 546
Aligned: 170
Modelled: 177
Confidence: 100.0%
Identity: 41%
PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution

Phyre2
3 |
| c1y57A_ |

### PDB 1y57 chain A

Region: 325 - 548
Aligned: 161
Modelled: 168
Confidence: 100.0%
Identity: 37%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor

Phyre2
4 |
| c1oplA_ |

### PDB 1opl chain A

Region: 327 - 548
Aligned: 158
Modelled: 166
Confidence: 100.0%
Identity: 37%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase

Phyre2
5 |
| c2h8hA_ |

### PDB 2h8h chain A

Region: 328 - 547
Aligned: 157
Modelled: 164
Confidence: 100.0%
Identity: 38%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor

Phyre2
6 |
| c2ablA_ |

### PDB 2abl chain A

Region: 320 - 543
Aligned: 160
Modelled: 168
Confidence: 100.0%
Identity: 36%
PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase

Phyre2
7 |
| c2c0iA_ |

### PDB 2c0i chain A

Region: 328 - 548
Aligned: 157
Modelled: 165
Confidence: 100.0%
Identity: 36%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983

Phyre2
8 |
| c1x27F_ |

### PDB 1x27 chain F

Region: 327 - 543
Aligned: 153
Modelled: 161
Confidence: 100.0%
Identity: 36%
PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas

Phyre2
9 |
| c3nhnA_ |

### PDB 3nhn chain A

Region: 327 - 543
Aligned: 154
Modelled: 161
Confidence: 100.0%
Identity: 36%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region

Phyre2
10 |
| c1g83A_ |

### PDB 1g83 chain A

Region: 327 - 541
Aligned: 152
Modelled: 159
Confidence: 100.0%
Identity: 38%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2

Phyre2
11 |
| c2b3oA_ |

### PDB 2b3o chain A

Region: 324 - 543
Aligned: 163
Modelled: 164
Confidence: 100.0%
Identity: 27%
PDB header:hydrolase
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1

Phyre2
12 |
| c3ps5A_ |

### PDB 3ps5 chain A

Region: 327 - 543
Aligned: 159
Modelled: 161
Confidence: 100.0%
Identity: 29%
PDB header:hydrolase, signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6;
PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1

Phyre2
13 |
| c2shpA_ |

### PDB 2shp chain A

Region: 324 - 543
Aligned: 163
Modelled: 164
Confidence: 100.0%
Identity: 23%
PDB header:tyrosine phosphatase
Chain: A: PDB Molecule:shp-2;
PDBTitle: tyrosine phosphatase shp-2

Phyre2
14 |
| c2ci8A_ |

### PDB 2ci8 chain A

Region: 447 - 542
Aligned: 96
Modelled: 96
Confidence: 100.0%
Identity: 60%
PDB header:translation
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed

Phyre2
15 |
| c2eo6A_ |

### PDB 2eo6 chain A

Region: 369 - 547
Aligned: 123
Modelled: 123
Confidence: 100.0%
Identity: 28%
PDB header:signaling protein
Chain: A: PDB Molecule:b-cell linker protein;
PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk

Phyre2
16 |
| d2shpa2 |

### PDB 2shp chain A domain 2

Region: 444 - 548
Aligned: 105
Modelled: 105
Confidence: 100.0%
Identity: 30%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
17 |
| c2eo3A_ |

### PDB 2eo3 chain A

Region: 369 - 544
Aligned: 109
Modelled: 116
Confidence: 100.0%
Identity: 35%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of the sh2 domain from human crk-like2 protein

Phyre2
18 |
| c2lqnA_ |

### PDB 2lqn chain A

Region: 437 - 548
Aligned: 111
Modelled: 112
Confidence: 100.0%
Identity: 28%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl

Phyre2
19 |
| c1x6cA_ |

### PDB 1x6c chain A

Region: 441 - 545
Aligned: 104
Modelled: 105
Confidence: 100.0%
Identity: 29%
PDB header:signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1

Phyre2
20 |
| c1griA_ |

### PDB 1gri chain A

Region: 153 - 385
Aligned: 202
Modelled: 210
Confidence: 100.0%
Identity: 23%
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2

Phyre2
21 |
22 |
23 |
24 |
25 |
26 |
27 |
28 |
29 |
30 |
31 |
32 |
33 |
34 |
35 |
36 |
37 |
38 |
39 |
40 |
41 |
42 |
43 |
44 |
45 |
46 |
47 |
48 |
49 |
50 |
51 |
52 |
53 |
54 |
55 |
56 |
57 |
58 |
59 |
60 |
61 |
62 |
63 |
64 |
65 |
66 |
67 |
68 |
69 |
70 |
71 |
72 |
73 |
74 |
75 |
76 |
77 |
78 |
79 |
80 |
81 |
82 |
83 |
84 |
85 |
86 |
87 |
88 |
89 |
90 |
91 |
92 |
93 |
94 |
| c2l3sA_ |

### PDB 2l3s chain A

Region: 152 - 310
Aligned: 159
Modelled: 159
Confidence: 99.9%
Identity: 20%
PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk

Phyre2
95 |
96 |
97 |
98 |
99 |
100 |
101 |
102 |
103 |
104 |
105 |
106 |
107 |
108 |
109 |
110 |
111 |
112 |
113 |
114 |
115 |
116 |
117 |
118 |
119 |
120 |
121 |
122 |
123 |
124 |
125 |
126 |
127 |
128 |
129 |
130 |
131 |
132 |
133 |
134 |
135 |
136 |
137 |
138 |
139 |
140 |
141 |
142 |
143 |
144 |
145 |
146 |
147 |
148 |
149 |
150 |
151 |
152 |
153 |
154 |
155 |
156 |
157 |
158 |
159 |
160 |
161 |
162 |
163 |
164 |
165 |
166 |
167 |
168 |
169 |
170 |
171 |
172 |
173 |
174 |
175 |
176 |
177 |
178 |
179 |
180 |
181 |
182 |
183 |
184 |
185 |
186 |
187 |
188 |
189 |
190 |
191 |
192 |
193 |
194 |
195 |
196 |
197 |
198 |
199 |
200 |
201 |
202 |
203 |
204 |
205 |
206 |
207 |
208 |
209 |
210 |
211 |
212 |
213 |
214 |
215 |
216 |
217 |
218 |
219 |
220 |
221 |
222 |
223 |
224 |
225 |
226 |
227 |
228 |
229 |
230 |
231 |
232 |
233 |
234 |
235 |
236 |
237 |
238 |
239 |
240 |
241 |
242 |
243 |
244 |
245 |
246 |
247 |
248 |
249 |
250 |
251 |
252 |
253 |
254 |
255 |
256 |
257 |
258 |
259 |
260 |
261 |
262 |
263 |
264 |
265 |
266 |
267 |
268 |
269 |
270 |
271 |
272 |
273 |
274 |
275 |
276 |
277 |
278 |
279 |
280 |
281 |
282 |
283 |
284 |
285 |
286 |
287 |
288 |
289 |
290 |
291 |
292 |
293 |
294 |
295 |
296 |
297 |
298 |
299 |
300 |
301 |
302 |
303 |
304 |
305 |
306 |
307 |
308 |
309 |
310 |
311 |
312 |
313 |
314 |
315 |
316 |
317 |
318 |
319 |
320 |
321 |
322 |
323 |
324 |
325 |
326 |
327 |
328 |
329 |
330 |
331 |
332 |
333 |
334 |
335 |
336 |
337 |
338 |
339 |
340 |
341 |
342 |
343 |
344 |
345 |
346 |
347 |
348 |
349 |
350 |
351 |
352 |
353 |
354 |
355 |
356 |
357 |
358 |
359 |
360 |
361 |
362 |
363 |
364 |
365 |
366 |
367 |
368 |
369 |
370 |
371 |
372 |
373 |
374 |
375 |
376 |
377 |
378 |
379 |

Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c2fo0A_ |
|  | 100.0 | 36 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
2 | c1k9aB_ |
|  | 100.0 | 41 | PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
3 | c1y57A_ |
|  | 100.0 | 37 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
4 | c1oplA_ |
|  | 100.0 | 37 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
5 | c2h8hA_ |
|  | 100.0 | 38 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor
6 | c2ablA_ |
|  | 100.0 | 36 | PDB header:transferase Chain: A: PDB Molecule:abl tyrosine kinase; PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
7 | c2c0iA_ |
|  | 100.0 | 36 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983
8 | c1x27F_ |
|  | 100.0 | 36 | PDB header:signaling protein Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck; PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
9 | c3nhnA_ |
|  | 100.0 | 36 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
10 | c1g83A_ |
|  | 100.0 | 38 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn; PDBTitle: crystal structure of fyn sh3-sh2
11 | c2b3oA_ |
|  | 100.0 | 27 | PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: crystal structure of human tyrosine phosphatase shp-1
12 | c3ps5A_ |
|  | 100.0 | 29 | PDB header:hydrolase, signaling protein Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6; PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
13 | c2shpA_ |
|  | 100.0 | 23 | PDB header:tyrosine phosphatase Chain: A: PDB Molecule:shp-2; PDBTitle: tyrosine phosphatase shp-2
14 | c2ci8A_ |
|  | 100.0 | 60 | PDB header:translation Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
15 | c2eo6A_ |
|  | 100.0 | 28 | PDB header:signaling protein Chain: A: PDB Molecule:b-cell linker protein; PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
16 | d2shpa2 |
|  | 100.0 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
17 | c2eo3A_ |
|  | 100.0 | 35 | PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
18 | c2lqnA_ |
|  | 100.0 | 28 | PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of crkl
19 | c1x6cA_ |
|  | 100.0 | 29 | PDB header:signaling protein Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
20 | c1griA_ |
|  | 100.0 | 23 | PDB header:signal transduction adaptor Chain: A: PDB Molecule:growth factor bound protein 2; PDBTitle: grb2
21 | c3hizB_ |
| not modelled | 100.0 | 29 | PDB header:transferase/oncoprotein Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
22 | c2crhA_ |
| not modelled | 100.0 | 21 | PDB header:signaling protein Chain: A: PDB Molecule:vav proto-oncogene; PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
23 | d3c7ia1 |
| not modelled | 100.0 | 33 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
24 | c2gsbA_ |
| not modelled | 100.0 | 29 | PDB header:signaling protein Chain: A: PDB Molecule:ras gtpase-activating protein 1; PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
25 | d2oq1a1 |
| not modelled | 100.0 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
26 | d1a81a1 |
| not modelled | 100.0 | 23 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
27 | c2dlyA_ |
| not modelled | 100.0 | 29 | PDB header:transferase Chain: A: PDB Molecule:fyn-related kinase; PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
28 | c2dlzA_ |
| not modelled | 100.0 | 25 | PDB header:signaling protein Chain: A: PDB Molecule:protein vav-2; PDBTitle: solution structure of the sh2 domain of human protein vav-2
29 | d1mila_ |
| not modelled | 100.0 | 24 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
30 | d1fhsa_ |
| not modelled | 100.0 | 32 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
31 | c2oq1A_ |
| not modelled | 100.0 | 27 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
32 | c2hdxB_ |
| not modelled | 100.0 | 26 | PDB header:signaling protein Chain: B: PDB Molecule:sh2-b ph domain containing signaling mediator 1 PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide
33 | c3gqiB_ |
| not modelled | 100.0 | 31 | PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:phospholipase c-gamma-1; PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
34 | d1a81e1 |
| not modelled | 99.9 | 23 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
35 | c2y3aB_ |
| not modelled | 99.9 | 31 | PDB header:transferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta; PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
36 | c2eobA_ |
| not modelled | 99.9 | 28 | PDB header:hydrolase Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
37 | d1rjaa_ |
| not modelled | 99.9 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
38 | c2el8A_ |
| not modelled | 99.9 | 22 | PDB header:signaling protein Chain: A: PDB Molecule:signal-transducing adaptor protein 2; PDBTitle: solution structure of the human stap2 sh2 domain
39 | c2kk6A_ |
| not modelled | 99.9 | 33 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fer; PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
40 | c1ka6A_ |
| not modelled | 99.9 | 26 | PDB header:immune system Chain: A: PDB Molecule:sh2 domain protein 1a; PDBTitle: sap/sh2d1a bound to peptide n-py
41 | d1ayaa_ |
| not modelled | 99.9 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
42 | d2izva2 |
| not modelled | 99.9 | 22 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
43 | d2oq1a2 |
| not modelled | 99.9 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
44 | d1d4ta_ |
| not modelled | 99.9 | 28 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
45 | c2ozoA_ |
| not modelled | 99.9 | 27 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
46 | d2eyva1 |
| not modelled | 99.9 | 31 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
47 | c1ng2A_ |
| not modelled | 99.9 | 20 | PDB header:oxidoreductase activator Chain: A: PDB Molecule:neutrophil cytosolic factor 1; PDBTitle: structure of autoinhibited p47phox
48 | c2vifA_ |
| not modelled | 99.9 | 29 | PDB header:signaling protein Chain: A: PDB Molecule:suppressor of cytokine signalling 6; PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide
49 | d1a81e2 |
| not modelled | 99.9 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
50 | d1a81a2 |
| not modelled | 99.9 | 32 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
51 | d1nrva_ |
| not modelled | 99.9 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
52 | c4fl2A_ |
| not modelled | 99.9 | 24 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch
53 | c2ysxA_ |
| not modelled | 99.9 | 29 | PDB header:signaling protein Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase PDBTitle: solution structure of the human ship sh2 domain
54 | d1jwoa_ |
| not modelled | 99.9 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
55 | d1pica_ |
| not modelled | 99.9 | 26 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
56 | d1csya_ |
| not modelled | 99.9 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
57 | d1r1qa_ |
| not modelled | 99.9 | 32 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
58 | d1opka2 |
| not modelled | 99.9 | 34 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
59 | d1blja_ |
| not modelled | 99.9 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
60 | d1jyra_ |
| not modelled | 99.9 | 36 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
61 | d2shpa3 |
| not modelled | 99.9 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
62 | d2fcia1 |
| not modelled | 99.9 | 31 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
63 | c2dcrA_ |
| not modelled | 99.9 | 32 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps; PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
64 | d1k9aa2 |
| not modelled | 99.9 | 31 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
65 | c2lctA_ |
| not modelled | 99.9 | 24 | PDB header:signaling protein Chain: A: PDB Molecule:proto-oncogene vav; PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
66 | c2hmhA_ |
| not modelled | 99.9 | 25 | PDB header:cytokine regulator Chain: A: PDB Molecule:suppressor of cytokine signaling 3; PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
67 | d1fu6a_ |
| not modelled | 99.9 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
68 | c1ov3A_ |
| not modelled | 99.9 | 24 | PDB header:oxidoreductase activator Chain: A: PDB Molecule:neutrophil cytosol factor 1; PDBTitle: structure of the p22phox-p47phox complex
69 | c2c9wA_ |
| not modelled | 99.9 | 28 | PDB header:transcription regulation Chain: A: PDB Molecule:suppressor of cytokine signaling 2; PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution
70 | c2izvA_ |
| not modelled | 99.9 | 22 | PDB header:transcription Chain: A: PDB Molecule:suppressor of cytokine signaling 4; PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution
71 | c2ge9A_ |
| not modelled | 99.9 | 27 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
72 | c2augB_ |
| not modelled | 99.9 | 27 | PDB header:signaling protein Chain: B: PDB Molecule:growth factor receptor-bound protein 14; PDBTitle: crystal structure of the grb14 sh2 domain
73 | d1lkka_ |
| not modelled | 99.9 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
74 | d1qcfa2 |
| not modelled | 99.9 | 33 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
75 | d1i3za_ |
| not modelled | 99.9 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
76 | d1o48a_ |
| not modelled | 99.9 | 32 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
77 | d2qmsa1 |
| not modelled | 99.9 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
78 | c1a81E_ |
| not modelled | 99.9 | 29 | PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
79 | d1qada_ |
| not modelled | 99.9 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
80 | d1f2fa_ |
| not modelled | 99.9 | 33 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
81 | c2knoA_ |
| not modelled | 99.9 | 29 | PDB header:hydrolase Chain: A: PDB Molecule:tensin-like c1 domain-containing phosphatase; PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
82 | c2eyzA_ |
| not modelled | 99.9 | 14 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform ii
83 | d1bkla_ |
| not modelled | 99.9 | 32 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
84 | d1g83a2 |
| not modelled | 99.9 | 34 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
85 | d1luia_ |
| not modelled | 99.9 | 29 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
86 | c2cr4A_ |
| not modelled | 99.9 | 20 | PDB header:signaling protein Chain: A: PDB Molecule:sh3 domain-binding protein 2; PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein
87 | d1rpya_ |
| not modelled | 99.9 | 25 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
88 | c1rqqC_ |
| not modelled | 99.9 | 25 | PDB header:transferase/signaling protein Chain: C: PDB Molecule:adaptor protein aps; PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
89 | d2cs0a1 |
| not modelled | 99.9 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
90 | c2ekxA_ |
| not modelled | 99.9 | 32 | PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx; PDBTitle: solution structure of the human bmx sh2 domain
91 | c3mazA_ |
| not modelled | 99.9 | 18 | PDB header:signaling protein Chain: A: PDB Molecule:signal-transducing adaptor protein 1; PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide
92 | d1xa6a2 |
| not modelled | 99.9 | 22 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
93 | d2c9wa2 |
| not modelled | 99.9 | 26 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
94 | c2l3sA_ |
|  | 99.9 | 20 | PDB header:structural protein Chain: A: PDB Molecule:autoinhibited crk protein; PDBTitle: structure of the autoinhibited crk
95 | d1cwea_ |
| not modelled | 99.9 | 31 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
96 | c2dvjA_ |
| not modelled | 99.9 | 29 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog, PDBTitle: phosphorylated crk-ii
97 | c2dm0A_ |
| not modelled | 99.9 | 22 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase txk; PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk
98 | c2eyyA_ |
| not modelled | 99.9 | 29 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform i
99 | c3qwyA_ |
| not modelled | 99.9 | 20 | PDB header:signaling protein Chain: A: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2
100 | c3qwxX_ |
| not modelled | 99.9 | 20 | PDB header:signaling protein Chain: X: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 1-174
101 | c3gxxB_ |
| not modelled | 99.9 | 21 | PDB header:transcription Chain: B: PDB Molecule:transcription elongation factor spt6; PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b
102 | c2dx0B_ |
| not modelled | 99.8 | 33 | PDB header:hydrolase Chain: B: PDB Molecule:phospholipase c, gamma 2; PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2
103 | c3or8A_ |
| not modelled | 99.8 | 24 | PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor spt6; PDBTitle: a tandem sh2 domain in transcription elongation factor spt6
104 | c2xp1A_ |
| not modelled | 99.8 | 18 | PDB header:transcription Chain: A: PDB Molecule:spt6; PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
105 | c1xa6A_ |
| not modelled | 99.8 | 27 | PDB header:signaling protein Chain: A: PDB Molecule:beta2-chimaerin; PDBTitle: crystal structure of the human beta2-chimaerin
106 | c2yt6A_ |
| not modelled | 99.8 | 33 | PDB header:cell cycle Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full- PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1
107 | d1uura3 |
| not modelled | 99.8 | 22 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
108 | c1mv3A_ |
| not modelled | 99.8 | 13 | PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:myc box dependent interacting protein 1; PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
109 | d1udla_ |
| not modelled | 99.7 | 31 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
110 | d1bf5a3 |
| not modelled | 99.7 | 17 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
111 | c1wx6A_ |
| not modelled | 99.7 | 37 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:cytoplasmic protein nck2; PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck2
112 | d1ng2a2 |
| not modelled | 99.6 | 16 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
113 | d1u5sa1 |
| not modelled | 99.6 | 47 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
114 | c2jxbA_ |
| not modelled | 99.6 | 27 | PDB header:signaling protein complex Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain, PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex
115 | c2dlpA_ |
| not modelled | 99.6 | 26 | PDB header:structural protein Chain: A: PDB Molecule:kiaa1783 protein; PDBTitle: solution structure of the sh3 domain of human kiaa17832 protein
116 | d1wiea_ |
| not modelled | 99.6 | 23 | Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain
117 | c1u3oA_ |
| not modelled | 99.6 | 30 | PDB header:signaling protein Chain: A: PDB Molecule:huntingtin-associated protein-interacting PDBTitle: solution structure of rat kalirin n-terminal sh3 domain
118 | c2e5kA_ |
| not modelled | 99.6 | 19 | PDB header:protein binding Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1; PDBTitle: solution structure of sh3 domain in suppressor of t-cell2 receptor signaling 1
119 | c1x2qA_ |
| not modelled | 99.6 | 27 | PDB header:signaling protein Chain: A: PDB Molecule:signal transducing adapter molecule 2; PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2
120 | c2dybA_ |
| not modelled | 99.6 | 21 | PDB header:oxidoreductase Chain: A: PDB Molecule:neutrophil cytosol factor 4; PDBTitle: the crystal structure of human p40(phox)

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction |

Transmembrane helices have been predicted in your sequence to adopt the topology shown below