|   |   |
174 | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | T | N | E | F | F | I | H | V | L | E | R | V | S | A | V | Y | Q | P | N | G | K | L | A | F | G | T | V | K | S | D | M | E | C | K | C | Q | I | S | G | M | P | L | L | L | L | S | L | R | P | G | T | K | L | G | N | V | R | F | H | Q | S | V | N | L | K | R | W | K | Q | H | P | D | Q | I | E | F | I | P | P |
| Query Conservation |   |
  |   |
|
|
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |
|   |
|   |   |   |   |   |
|
|
|   |
|   |   |   |
|   |
|   |   |   |   |   |
|   |
|   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |
|   |   |   |   |
|   |
|
|   |
|   |
|   |
|   |
|   |   |
|
|   |
|
|
|   |
|   |   |   |
|   |
|
| . | . | . | . | . | . |
|   |
|
|
|   |
|
|   |
|   | . | . | . | . | . | . |
|   |
|
|
|
|
|
|
| Template Sequence |   |
S | R | N | E | L | F | L | D | V | L | E | S | V | N | L | L | M | S | P | Q | G | Q | V | L | S | A | H | V | S | G | R | V | V | M | K | S | Y | L | S | G | M | P | E | C | K | F | G | M | N | . |
. |
. |
. |
. |
. |
D | C | T | F | H | Q | C | V | R | L | S | . |
. |
. |
. |
. |
. |
R | S | I | S | F | I | P | P |
| Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S |
|
|  |  |  |  |  |  |
| . | . | . | . | . | . |
|
|
| B |
| T | T |  |  |
|
| . | . | . | . | . | . |
|  |  |  |  |
|
|
|
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
| . | . | . | . | . | . |
|
|  |  |
|
|
|
|
|
|
| . | . | . | . | . | . |
|  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1169 | 1170 | . | . | . | . | . | . | . | . | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200 | . | . | . | . | . | . | . | . | . | 1210 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 1220 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 1230 | . | . | . | . | . | . |
|   |
|   |   |
254 | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | |
|
|
|
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
| . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
D | G | K | F | T | L | A | S | F | Q | T | D | F | A | T | Q | K | S | L | P | V | V | V | E | A | K | . |
. |
. |
. |
N | K | L | D | G | R | F | E | V | R | I | R | N | T | G | K | K | S | V | E | N | L | K | I | L | I | T | I | P | Q | A | L | K | S | V | T | V | T | E | G | N | Y | I | F | R | A | S | K | Y | T |
| Query Conservation |   |
|
|   |
|   |
|
|   |
|   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
| Template Conservation |   |
|
|   |
|   |
|
|   |
|
|
|   |   |   |   |   |
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |
|   |   |   |   |   |   |   |
|   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   | . | . | . | . |
|
| Template Sequence |   |
D | G | E | F | E | L | M | R | Y | R | T | T | K | D | I | I | L | P | F | R | V | I | P | L | V | R | E | V | G | R | T | K | L | E | V | K | V | V | I | K | S | N | F | K | P | S | L | L | A | Q | K | I | E | V | R | I | P | T | P | L | N | T | S | G | V | Q | V | I | C | M | K | G | K | A | K | . |
. |
. |
. |
Y |
| Template Known Secondary structure |   |
S |  |  |  |  |  |  |  |  |  |  |
| S | S |
|
|
| S |  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |  |  |  |
| S |
| T | T |
|
|  |  |  |  |  |  |  |  |  |
|
| T | T |  |  |  |  |  |  |  |  | S | S | S |  |  |  | . | . | . | . |  |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1269 | 1270 | . | . | . | . | . | . | . | . | . | 1280 | . | . | . | . | . | . | . | . | . | 1290 | . | . | . | . | . | . | . | . | . | 1300 | . | . | . | . | . | . | . | . | . | 1310 | . | . | . | . | . | . | . | . | . | 1320 | . | . | . | . | . | . | . | . | . | 1330 | . | . | . | . | . | . | . | . | . | 1340 | . | . | . | |
|
|
|
. |
|   |
|   |   |
330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | |
|
|
|
. | . | . |
| Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
| Query Sequence |   |
H | M | E | E | G | I | L | E | W | S | V | K | K | L | A | W | T | S | P | A | L | V | L | T | G | F | L | A | P | L | K | K | D | A | N | S | T | E | E | S | S | S | Y | S | K | L | E | H | L | D | L | Q | Y | K | L | Q | G | S | T | L | H | N | F | K | V | E | S | L | K | M | L | N | H | . |
. |
. |
. |
P | D | K |
| Query Conservation |   |
  |   |   |   |   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |   |   |   |
|
|
|   |
|   |   |
|   |
|   |   |   | . | . | . | . |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |
|
|
|   |
|   |
|
|   |
|   |   |   |   |   |
|   |   |   |
|   |
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|
|
|   |
|
|
|
| . |   |
|   |
|
|
|   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
K | A | S | E | N | A | I | V | W | K | I | K | R | M | A | G | M | K | E | S | Q | I | S | A | E | I | E | L | L | P | T | W | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | P | P | I | S | M | N | F | E | V | P | . |
F | A | P | S | G | L | K | V | R | Y | L | K | V | F | E | P | K | L | N | Y | S | D | H |
| Template Known Secondary structure |   |
 | G | G | G | T |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |
|  |  | S | . | S |
| T | T |
|
|
|  |  |  |  |  |  |  |
| S | S | S | S |
|
| G | G |
| Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  | . |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1345 | . | . | . | . | 1350 | . | . | . | . | . | . | . | . | . | 1360 | . | . | . | . | . | . | . | . | . | 1370 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | 1380 | . | . | . | . | . | . | . | . | |
. | 1390 | . | . | . | . | . | . | . | . | . | 1400 | . | . | . | . | . | . | . | . | . | 1410 | . |
|   |
|   |   |
406 | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | S | Y | K | G | V | K | H | T | I | I | A | Q | N | V | S | F | R |
| Query Conservation |   |
|   |   |
|   |
|
|
|   |
|   |
|
|   |
|   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|   |
|
|
|
|
|
|
|   |
|
|   |
|   |
|
|
| Template Sequence |   |
D | V | I | K | W | V | R | Y | I | G | R | S | G | I | Y | E | T | R |
| Template Known Secondary structure |   |
G |
|  |  |  |
|
| B |
|  |  |  |  |  |  |  |  |
|
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1417 | . | . | 1420 | . | . | . | . | . | . | . | . | . | 1430 | . | . | . | . |
|   |