Phyre 2 Results for C1P620

Phyre Home | Retrieve Phyre Job Id

Email | l.a.kelley@imperial.ac.uk
Description | C1P620
Date | Thu Jan 5 10:56:18 GMT 2012
Unique Job ID | cc4a817a90df346e

Summary |

Top model
Image coloured by rainbow N → C terminus
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Model (left) based on template d1wxia1
Top template information
Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
Confidence and coverage
Confidence: | 37.7% | Coverage: | 50%
18 residues ( 50% of your sequence) have been modelled with 37.7% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
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3D viewing
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Sequence analysis |

Secondary structure and disorder prediction |

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Sequence |  | M | L | E | S | I | I | N | L | V | S | S | G | A | V | D | S | H | T | P | Q | T | A | V | A | A | V | L | C | A | A | M | I | G | L | F | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| d1wxia1 |

### PDB 1wxi chain A domain 1

Region: 11 - 33
Aligned: 18
Modelled: 23
Confidence: 37.7%
Identity: 44%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Adenine nucleotide alpha hydrolases-like
Family: N-type ATP pyrophosphatases

Phyre2
2 |
| c3dpiA_ |

### PDB 3dpi chain A

Region: 11 - 33
Aligned: 18
Modelled: 23
Confidence: 18.4%
Identity: 33%
PDB header:ligase
Chain: A: PDB Molecule:nad+ synthetase;
PDBTitle: crystal structure of nad+ synthetase from burkholderia pseudomallei

Phyre2
3 |
| c3q4gA_ |

### PDB 3q4g chain A

Region: 11 - 33
Aligned: 18
Modelled: 23
Confidence: 16.4%
Identity: 33%
PDB header:ligase
Chain: A: PDB Molecule:nh(3)-dependent nad(+) synthetase;
PDBTitle: structure of nad synthetase from vibrio cholerae

Phyre2
4 |
| c3uowB_ |

### PDB 3uow chain B

Region: 11 - 33
Aligned: 18
Modelled: 23
Confidence: 10.6%
Identity: 39%
PDB header:ligase
Chain: B: PDB Molecule:gmp synthetase;
PDBTitle: crystal structure of pf10_0123, a gmp synthetase from plasmodium2 falciparum

Phyre2
5 |
| c1gpmD_ |

### PDB 1gpm chain D

Region: 11 - 33
Aligned: 18
Modelled: 23
Confidence: 9.4%
Identity: 56%
PDB header:transferase (glutamine amidotransferase)
Chain: D: PDB Molecule:gmp synthetase;
PDBTitle: escherichia coli gmp synthetase complexed with amp and pyrophosphate

Phyre2
6 |
| d1kqpa_ |

### PDB 1kqp chain A

Region: 11 - 34
Aligned: 19
Modelled: 24
Confidence: 6.6%
Identity: 32%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Adenine nucleotide alpha hydrolases-like
Family: N-type ATP pyrophosphatases

Phyre2

Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | d1wxia1 |
|  | 37.7 | 44 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases
2 | c3dpiA_ |
|  | 18.4 | 33 | PDB header:ligase Chain: A: PDB Molecule:nad+ synthetase; PDBTitle: crystal structure of nad+ synthetase from burkholderia pseudomallei
3 | c3q4gA_ |
|  | 16.4 | 33 | PDB header:ligase Chain: A: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: structure of nad synthetase from vibrio cholerae
4 | c3uowB_ |
|  | 10.6 | 39 | PDB header:ligase Chain: B: PDB Molecule:gmp synthetase; PDBTitle: crystal structure of pf10_0123, a gmp synthetase from plasmodium2 falciparum
5 | c1gpmD_ |
|  | 9.4 | 56 | PDB header:transferase (glutamine amidotransferase) Chain: D: PDB Molecule:gmp synthetase; PDBTitle: escherichia coli gmp synthetase complexed with amp and pyrophosphate
6 | d1kqpa_ |
|  | 6.6 | 32 | Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0