Email l.a.kelley@imperial.ac.uk Description O13527 Date Mon Jul 2 19:10:08 BST 2012 Unique Job ID d56b1bd2d8233ff8

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1c0mA_ 100.0 19 PDB header:transferase Chain: A: PDB Molecule:protein (integrase); PDBTitle: crystal structure of rsv two-domain integrase 2 d1asua_ 100.0 18 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Retroviral integrase, catalytic domain 3 c3f9kV_ 100.0 10 PDB header:viral protein, recombination Chain: V: PDB Molecule:integrase; PDBTitle: two domain fragment of hiv-2 integrase in complex with ledgf ibd 4 d1c0ma2 100.0 19 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Retroviral integrase, catalytic domain 5 c3l2tB_ 100.0 20 PDB header:recombination/dna Chain: B: PDB Molecule:integrase; PDBTitle: crystal structure of the prototype foamy virus (pfv) intasome in2 complex with magnesium and mk0518 (raltegravir) 6 c1ex4A_ 100.0 14 PDB header:viral protein Chain: A: PDB Molecule:integrase; PDBTitle: hiv-1 integrase catalytic core and c-terminal domain 7 c1k6yB_ 100.0 16 PDB header:transferase Chain: B: PDB Molecule:integrase; PDBTitle: crystal structure of a two-domain fragment of hiv-1 integrase 8 c3hpgC_ 99.9 18 PDB header:transferase Chain: C: PDB Molecule:integrase; PDBTitle: visna virus integrase (residues 1-219) in complex with ledgf2 ibd: examples of open integrase dimer-dimer interfaces 9 c3dlrA_ 99.9 21 PDB header:transferase Chain: A: PDB Molecule:integrase; PDBTitle: crystal structure of the catalytic core domain from pfv2 integrase 10 c3kksB_ 99.9 13 PDB header:dna binding protein Chain: B: PDB Molecule:integrase; PDBTitle: crystal structure of catalytic core domain of biv integrase in crystal2 form ii 11 c3nf9A_ 99.9 16 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:integrase; PDBTitle: structural basis for a new mechanism of inhibition of hiv integrase2 identified by fragment screening and structure based design 12 d1cxqa_ 99.9 19 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Retroviral integrase, catalytic domain 13 d1exqa_ 99.9 14 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Retroviral integrase, catalytic domain 14 d1hyva_ 99.9 16 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Retroviral integrase, catalytic domain 15 d1c6va_ 99.9 10 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Retroviral integrase, catalytic domain 16 c1rthA_ 99.5 16 PDB header:nucleotidyltransferase Chain: A: PDB Molecule:hiv-1 reverse transcriptase; PDBTitle: high resolution structures of hiv-1 rt from four rt-2 inhibitor complexes 17 c1mu2A_ 99.5 21 PDB header:transferase Chain: A: PDB Molecule:hiv-2 rt; PDBTitle: crystal structure of hiv-2 reverse transcriptase 18 d2zd1b1 99.3 14 Fold:DNA/RNA polymerases Superfamily:DNA/RNA polymerases Family:Reverse transcriptase 19 c3kk1B_ 99.3 15 PDB header:transferase/dna Chain: B: PDB Molecule:reverse transcriptase p51 subunit; PDBTitle: hiv-1 reverse transcriptase-dna complex with nuceotide inhibitor gs-2 9148-diphosphate bound in nucleotide site 20 d1mu2a2 99.2 17 Fold:DNA/RNA polymerases Superfamily:DNA/RNA polymerases Family:Reverse transcriptase 21 d1bcoa2 not modelled 99.1 14 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:mu transposase, core domain 22 c1bcoA_ not modelled 98.9 15 PDB header:transposase Chain: A: PDB Molecule:bacteriophage mu transposase; PDBTitle: bacteriophage mu transposase core domain 23 c2opqA_ not modelled 98.8 14 PDB header:transferase Chain: A: PDB Molecule:reverse transcriptase/ribonuclease h; PDBTitle: crystal structure of l100i mutant hiv-1 reverse2 transcriptase in complex with gw420867x. 24 d1ztwa1 not modelled 98.6 12 Fold:DNA/RNA polymerases Superfamily:DNA/RNA polymerases Family:Reverse transcriptase 25 d1hara_ not modelled 98.2 18 Fold:DNA/RNA polymerases Superfamily:DNA/RNA polymerases Family:Reverse transcriptase 26 c2ehgA_ not modelled 98.1 15 PDB header:hydrolase Chain: A: PDB Molecule:ribonuclease hi; PDBTitle: crystal structure of hyperthermophilic archaeal rnase hi 27 c3hstD_ not modelled 98.1 11 PDB header:hydrolase Chain: D: PDB Molecule:protein rv2228c/mt2287; PDBTitle: n-terminal rnase h domain of rv2228c from mycobacterium tuberculosis2 as a fusion protein with maltose binding protein 28 d1jl2a_ not modelled 97.9 21 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Ribonuclease H 29 d1rw3a_ not modelled 97.9 14 Fold:DNA/RNA polymerases Superfamily:DNA/RNA polymerases Family:Reverse transcriptase 30 c2qkkI_ not modelled 97.8 15 PDB header:hydrolase/dna/rna Chain: I: PDB Molecule:ribonuclease h1; PDBTitle: human rnase h catalytic domain mutant d210n in complex with2 14-mer rna/dna hybrid 31 c2kq2A_ not modelled 97.7 18 PDB header:hydrolase Chain: A: PDB Molecule:ribonuclease h-related protein; PDBTitle: solution nmr structure of the apo form of a ribonuclease h2 domain of protein dsy1790 from desulfitobacterium3 hafniense, northeast structural genomics target dhr1a 32 d1s9ga1 not modelled 97.6 16 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Ribonuclease H 33 c3u3gA_ not modelled 97.6 18 PDB header:hydrolase Chain: A: PDB Molecule:ribonuclease h; PDBTitle: structure of lc11-rnase h1 isolated from compost by metagenomic2 approach: insight into the structural bases for unusual enzymatic3 properties of sto-rnase h1 34 c2hb5A_ not modelled 97.5 16 PDB header:hydrolase Chain: A: PDB Molecule:reverse transcriptase/ribonuclease h; PDBTitle: crystal structure of the moloney murine leukemia virus2 rnase h domain 35 d1wsib_ not modelled 97.5 20 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Ribonuclease H 36 d1jlaa1 not modelled 97.5 14 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Ribonuclease H 37 d1s1ta1 not modelled 97.5 15 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Ribonuclease H 38 c2e4lA_ not modelled 97.5 21 PDB header:hydrolase Chain: A: PDB Molecule:ribonuclease hi; PDBTitle: thermodynamic and structural analysis of thermolabile rnase hi from2 shewanella oneidensis mr-1 39 d1jl1a_ not modelled 97.5 20 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Ribonuclease H 40 c3h08B_ not modelled 97.4 16 PDB header:hydrolase Chain: B: PDB Molecule:rnh (ribonuclease h); PDBTitle: crystal structure of the ribonuclease h1 from chlorobium2 tepidum 41 d1rila_ not modelled 97.3 13 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Ribonuclease H 42 d1mu2a1 not modelled 97.3 15 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Ribonuclease H 43 d1o1wa_ not modelled 97.2 17 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Ribonuclease H 44 c3hosA_ not modelled 97.2 7 PDB header:transferase, dna binding protein/dna Chain: A: PDB Molecule:transposable element mariner, complete cds; PDBTitle: crystal structure of the mariner mos1 paired end complex with mg 45 d1eeta1 not modelled 97.2 13 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Ribonuclease H 46 d1zbfa1 not modelled 94.7 15 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Ribonuclease H 47 c2rpiA_ not modelled 90.1 24 PDB header:hydrolase Chain: A: PDB Molecule:ribonuclease h; PDBTitle: the nmr structure of the submillisecond folding2 intermediate of the thermus thermophilus ribonuclease h 48 c3f2kB_ not modelled 80.0 5 PDB header:transferase Chain: B: PDB Molecule:histone-lysine n-methyltransferase setmar; PDBTitle: structure of the transposase domain of human histone-lysine2 n-methyltransferase setmar 49 d1sqha_ not modelled 70.7 8 Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:Hypothetical protein cg14615-pa 50 c3du6A_ not modelled 60.0 19 PDB header:transferase Chain: A: PDB Molecule:telomerase reverse transcriptase; PDBTitle: structure of the catalytic subunit of telomerase, tert 51 d2d81a1 not modelled 48.3 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:PHB depolymerase-like 52 c2zf8A_ not modelled 46.2 21 PDB header:structural protein Chain: A: PDB Molecule:component of sodium-driven polar flagellar motor; PDBTitle: crystal structure of moty 53 c2jtmA_ not modelled 27.9 24 PDB header:dna binding protein Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: solution structure of sso6901 from sulfolobus solfataricus2 p2 54 d2hqsc1 not modelled 27.8 12 Fold:Bacillus chorismate mutase-like Superfamily:OmpA-like Family:OmpA-like 55 d2pt0a1 not modelled 27.7 16 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Myo-inositol hexaphosphate phosphohydrolase (phytase) PhyA 56 c1u24A_ not modelled 23.2 16 PDB header:hydrolase Chain: A: PDB Molecule:myo-inositol hexaphosphate phosphohydrolase; PDBTitle: crystal structure of selenomonas ruminantium phytase 57 c2k1sA_ not modelled 21.9 7 PDB header:lipoprotein Chain: A: PDB Molecule:inner membrane lipoprotein yiad; PDBTitle: solution nmr structure of the folded c-terminal fragment of yiad from2 escherichia coli. northeast structural genomics consortium target3 er553. 58 d2aizp1 not modelled 20.9 7 Fold:Bacillus chorismate mutase-like Superfamily:OmpA-like Family:OmpA-like 59 c3nnqA_ not modelled 20.1 22 PDB header:viral protein Chain: A: PDB Molecule:n-terminal domain of moloney murine leukemia virus PDBTitle: crystal structure of the n-terminal domain of moloney murine leukemia2 virus integrase, northeast structural genomics consortium target or3 60 c2b9kA_ not modelled 19.8 26 PDB header:antibiotic Chain: A: PDB Molecule:antimicrobial peptide lci; PDBTitle: solution structure of lci, an amp from bacillus subtilis 61 c3g3sA_ not modelled 18.6 14 PDB header:transferase Chain: A: PDB Molecule:gcn5-related n-acetyltransferase; PDBTitle: crystal structure of gcn5-related n-acetyltransferase-like protein2 (zp_00874857) (zp_00874857.1) from streptococcus suis 89/1591 at 1.803 a resolution 62 c3dcgF_ not modelled 18.4 25 PDB header:ligase/viral protein Chain: F: PDB Molecule:virion infectivity factor; PDBTitle: crystal structure of the hiv vif bc-box in complex with human elonginb2 and elonginc 63 c2kgwA_ not modelled 18.2 10 PDB header:membrane protein Chain: A: PDB Molecule:outer membrane protein a; PDBTitle: solution structure of the carboxy-terminal domain of ompatb, a pore2 forming protein from mycobacterium tuberculosis 64 c2l26A_ not modelled 17.9 9 PDB header:membrane protein Chain: A: PDB Molecule:uncharacterized protein rv0899/mt0922; PDBTitle: rv0899 from mycobacterium tuberculosis contains two separated domains 65 d1wwia1 not modelled 17.8 9 Fold:Histone-fold Superfamily:Histone-fold Family:Bacterial histone-fold protein 66 c2pdoG_ not modelled 17.6 15 PDB header:transferase Chain: G: PDB Molecule:acetyltransferase ypea; PDBTitle: crystal structure of the putative acetyltransferase of gnat family2 from shigella flexneri 67 c3cjeA_ not modelled 17.2 3 PDB header:oxidoreductase Chain: A: PDB Molecule:osmc-like protein; PDBTitle: crystal structure of an osmc-like hydroperoxide resistance protein2 (jann_2040) from jannaschia sp. ccs1 at 1.70 a resolution 68 d1fgja_ not modelled 17.1 16 Fold:Multiheme cytochromes Superfamily:Multiheme cytochromes Family:Di-heme elbow motif 69 c1fgjA_ not modelled 17.1 16 PDB header:oxidoreductase Chain: A: PDB Molecule:hydroxylamine oxidoreductase; PDBTitle: x-ray structure of hydroxylamine oxidoreductase 70 c2f7tA_ not modelled 17.0 8 PDB header:dna binding protein Chain: A: PDB Molecule:mos1 transposase; PDBTitle: crystal structure of the catalytic domain of mos1 mariner2 transposase 71 c2cntD_ not modelled 16.7 9 PDB header:transferase Chain: D: PDB Molecule:modification of 30s ribosomal subunit protein s18; PDBTitle: rimi - ribosomal s18 n-alpha-protein acetyltransferase in2 complex with coenzymea. 72 d1ecfa1 not modelled 16.3 22 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 73 c2yc2D_ not modelled 16.1 10 PDB header:transport protein Chain: D: PDB Molecule:small rab-related gtpase; PDBTitle: intraflagellar transport complex 25-27 from chlamydomonas 74 c2qiyC_ not modelled 15.9 50 PDB header:signaling protein/hydrolase Chain: C: PDB Molecule:ubiquitin carboxyl-terminal hydrolase 3; PDBTitle: yeast deubiquitinase ubp3 and bre5 cofactor complex 75 c2jeuA_ not modelled 15.3 23 PDB header:transcription Chain: A: PDB Molecule:regulatory protein e2; PDBTitle: transcription activator structure reveals redox control of2 a replication initiation reaction 76 c3e0dA_ not modelled 14.9 22 PDB header:transferase/dna Chain: A: PDB Molecule:dna polymerase iii subunit alpha; PDBTitle: insights into the replisome from the crystral structure of2 the ternary complex of the eubacterial dna polymerase iii3 alpha-subunit 77 d1z3aa1 not modelled 14.2 25 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Deoxycytidylate deaminase-like 78 c3c5iD_ not modelled 14.1 13 PDB header:transferase Chain: D: PDB Molecule:choline kinase; PDBTitle: crystal structure of plasmodium knowlesi choline kinase, pkh_134520 79 c1trlB_ not modelled 14.0 22 PDB header:hydrolase (metalloprotease) Chain: B: PDB Molecule:thermolysin fragment 255 - 316; PDBTitle: nmr solution structure of the c-terminal fragment 255-3162 of thermolysin: a dimer formed by subunits having the3 native structure 80 c1tueG_ not modelled 13.7 18 PDB header:replication Chain: G: PDB Molecule:regulatory protein e2; PDBTitle: the x-ray structure of the papillomavirus helicase in2 complex with its molecular matchmaker e2 81 c1jr2A_ not modelled 13.6 24 PDB header:lyase Chain: A: PDB Molecule:uroporphyrinogen-iii synthase; PDBTitle: structure of uroporphyrinogen iii synthase 82 d1jr2a_ not modelled 13.6 24 Fold:HemD-like Superfamily:HemD-like Family:HemD-like 83 d1u09a_ not modelled 13.5 11 Fold:DNA/RNA polymerases Superfamily:DNA/RNA polymerases Family:RNA-dependent RNA-polymerase 84 d1raja_ not modelled 13.2 13 Fold:DNA/RNA polymerases Superfamily:DNA/RNA polymerases Family:RNA-dependent RNA-polymerase 85 c2dbqA_ not modelled 13.0 10 PDB header:oxidoreductase Chain: A: PDB Molecule:glyoxylate reductase; PDBTitle: crystal structure of glyoxylate reductase (ph0597) from pyrococcus2 horikoshii ot3, complexed with nadp (i41) 86 d1w79a1 not modelled 12.9 16 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Dac-like 87 d1gph11 not modelled 12.8 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 88 d1qqha_ not modelled 12.8 18 Fold:E2 regulatory, transactivation domain Superfamily:E2 regulatory, transactivation domain Family:E2 regulatory, transactivation domain 89 c3f2rA_ not modelled 12.7 14 PDB header:transferase Chain: A: PDB Molecule:choline kinase alpha; PDBTitle: crystal structure of human choline kinase alpha in complex2 with hemicholinium-3 90 c3td4D_ not modelled 12.0 11 PDB header:membrane protein,peptide binding protein Chain: D: PDB Molecule:outer membrane protein omp38; PDBTitle: crystal structure of ompa-like domain from acinetobacter baumannii in2 complex with diaminopimelate 91 c2yt5A_ not modelled 11.7 18 PDB header:transcription Chain: A: PDB Molecule:metal-response element-binding transcription PDBTitle: solution structure of the phd domain of metal-response2 element-binding transcription factor 2 92 c1lqlE_ not modelled 11.5 3 PDB header:unknown function Chain: E: PDB Molecule:osmotical inducible protein c like family; PDBTitle: crystal structure of osmc like protein from mycoplasma2 pneumoniae 93 d1lqla_ not modelled 11.5 3 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 94 c2lezA_ not modelled 11.3 12 PDB header:signaling protein Chain: A: PDB Molecule:secreted effector protein pipb2; PDBTitle: solution nmr structure of n-terminal domain of salmonella effector2 protein pipb2. northeast structural genomics consortium (nesg) target3 stt318a 95 d1ufra_ not modelled 11.1 19 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 96 c1qqgA_ not modelled 11.0 24 PDB header:signal transduction Chain: A: PDB Molecule:insulin receptor substrate 1; PDBTitle: crystal structure of the ph-ptb targeting region of irs-1 97 c2px2B_ not modelled 10.7 21 PDB header:transferase Chain: B: PDB Molecule:genome polyprotein [contains: capsid protein c PDBTitle: crystal structure of the murray valley encephalitis virus2 ns5 2'-o methyltransferase domain in complex with sah3 (monoclinic form 1) 98 d2ffja1 not modelled 10.7 15 Fold:AF1104-like Superfamily:AF1104-like Family:AF1104-like 99 d1ckqa_ not modelled 10.6 22 Fold:Restriction endonuclease-like Superfamily:Restriction endonuclease-like Family:Restriction endonuclease EcoRI