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Job DescriptionO13527
Confidence99.54%DateMon Jul 2 19:10:08 BST 2012
Rank16Aligned Residues378
% Identity16%Templatec1rthA_
PDB info PDB header:nucleotidyltransferaseChain: A: PDB Molecule:hiv-1 reverse transcriptase; PDBTitle: high resolution structures of hiv-1 rt from four rt-2 inhibitor complexes
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   692.......700.........710.. .......720.........730.........740.... .....750.........760
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Query Sequence  IEAYHKEVNQLLKMNTWDTDK. YYDRKEIDPKRVINSMFIFNKKRDGTHKARFV. . . . . . . . . . ARGDIQHPDTYDTGMQ
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Template Sequence  IKALVEICTEMEKEGKISKIGPENPYNTP. . . . . . . . . . VFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAG.
Template Known Secondary structure  TTS

SS


BB
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TT
SS


B


S
S

S


GGG.
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   31........40.........50......... 60.........70.........80.........90.........
 
   761........770.........780.........790.........800. ........810.........820.........830.....
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Query Sequence  SNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEEL. . . . . YIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYET
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Template Sequence  . . . . . . . . . . . . . . . . LKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSS
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S
GGGTTTSB

TTGGGGG


TT

S

SB

TT
TT
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   100.........110.........120.........130.........140.........150.........160...
 
   836...840.........850.........860.........870...... ...880.........890.........900.........910
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Query Sequence  IKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKD. . . . . LNANKKIITTLKKQYDTKIINLGESDNEIQYDIL
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Template Sequence  MTKIL. EPF. . . . . . . . . . RKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHL. LRWGLT. TPDKKHQKEPPFLWM
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TTTT
S
.TT

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GGG


SST
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   164.... .170. ........180.........190.........200......... 210..... ....220.........230
 
   911........920.........930.........940.........950.........960.........970.........980.........990
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Query Sequence  GLEIKYQRGKYMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYK
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Template Sequence  GYELH. . . PDKW. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TVQPIVLPEKDSWTVNDIQKLVGKLNWASQ.
Template Known Secondary structure  T...TT.....................................







SSTT.
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   231.... .... 240.........250.........260.........
 
   991........1000........ .1010.........1020.........1030..
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Query Sequence  FRFDLLYYINTLAQHILF. . . . . . PSRQVLDMTYELIQFMWDTRDKQL. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  IYPGIKVRQLKLLRGTKALTEVIPLTEEAELELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLK
Template Known Secondary structure  TSTT


S


TTTT


TT



TTS





TTS

TTTT
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   270.........280.........290.........300.........310.........320.........330.........340.........
 
   1033.....
Predicted Secondary structure  ..........................................................................


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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . IWHKNK
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Template Conservation                               
          
                                       
Template Sequence  TGKYARMRGAHTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLE
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SS

SS




S


SS








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   351........360.........370.........380.........390.........400.........410.........420.........430
 
   10391040.........1050.........1060.........1070.........1080.........1090.........1100.........1110........
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Query Sequence  PTEPDNKLVAISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSYLIQELNKKP
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Template Sequence  KEPIVGAETFYVDGA. . . . ANRETKLGKAGYVTNRGRQKVVTLTDT. . . TNQKTELQAIYLALQD. . . . . . . . . . . . . SG
Template Known Secondary structure  SS

TTS....TTTTTTS
SS
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   431........440..... ....450.........460.........470.. .......480........ .490
 
   11191120.........1130.........1140.........1150.........1160.........1170....
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Query Sequence  IIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNI
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Template Sequence  LEVNIVTDSQYALGIIQAQ. . . . PDQSESELVNQIIEQLIKKEKVYLAWVPAHKGI
Template Known Secondary structure  S


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S

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   491........500......... 510.........520.........530.........540..
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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