|   |   |
24 | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | K | A | T | F | D | S | S | K | K | K | E | V | G | V | S | D | L | T | L | L | S | K | I | S | D | E | A | I | N | E | N | L | K | K | R | F | L | N | A | T | I | Y | T | Y | I | G | H | V | L | I | S | V | N | P | F | R | D | L | G | I | Y | T | D | A | V | M | N | E | Y | K | G | K | N | R | L | E | V | P | P |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |
|
|
|   |   |
|   |   |
|
|   |
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |
|
|   |   |
|   |   |
|   |
|   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |
|
|
|   |   |
|   |
|
|
|
|
|
|
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
| Template Sequence |   |
T | V | S | D | K | R | R | N | P | I | K | F | D | G | V | E | D | M | S | E | L | S | Y | L | N | E | P | A | V | F | H | N | L | R | V | R | Y | N | Q | D | L | I | Y | T | Y | S | G | L | F | L | V | A | V | N | P | F | K | R | I | P | I | Y | T | Q | E | M | V | D | I | F | K | G | R | R | R | N | E | V | A | P |
| Template Known Secondary structure |   |
|
|
|
|
|
|
|
|
| T | T | S | T | T |
| S | B | G | G | G |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  | T | T |  |  |  |  |  |
|
| S | S |
|
| S |
|
| S |  |  |  |  |  |  |  | T | T |
|
| T | T | T | S |
|
|
| Template Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
28 | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . |
|   |
|   |   |
104 | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
H | V | F | A | I | A | E | S | M | Y | Y | N | M | K | S | Y | N | E | N | Q | C | V | I | I | S | G | E | S | G | A | G | K | T | E | A | A | K | R | I | M | Q | Y | I | A | A | A | S | S | T | H | T | E | S | I | G | K | I | K | D | M | V | L | A | T | N | P | L | L | E | S | F | G | C | A | K | T | L | R | N | N |
| Query Conservation |   |
|
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|
|
|
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |
|
|   |
|
|   |   |   |
|   |   | . | . | . | . | . | . | . |
|   |   |   |
|   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |
| Template Sequence |   |
H | I | F | A | I | S | D | V | A | Y | R | S | M | L | D | D | R | Q | N | Q | S | L | L | I | T | G | E | S | G | A | G | K | T | E | N | T | K | K | V | I | Q | Y | L | A | S | V | A | G | V | . |
. |
. |
. |
. |
. |
. |
L | E | Q | Q | I | L | Q | A | N | P | I | L | E | A | F | G | N | A | K | T | T | R | N | N |
| Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
| B |
| S | T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  | T | T |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
154 | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . |
|   |
|   |   |
184 | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
N | S | S | R | H | G | K | Y | L | E | I | K | F | N | N | Q | F | E | P | C | A | G | N | I | T | N | Y | L | L | E | K | Q | R | V | V | S | Q | I | K | N | E | R | N | F | H | I | F | Y | Q | F | T | K | G | A | S | D | A | Y | R | Q | T | F | G | V | Q | K | P | E | Q | Y | V | Y | T | A | A | A | G | C | I | S |
| Query Conservation |   |
|
|
|
|
|
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|
|
|
|
|
|   |   |   |
|   |
|   |   |   |
|   |
|   |
|
|   |
|   |   |
|
|
|
|
|
|
|
|
|   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |
| Template Sequence |   |
N | S | S | R | F | G | K | F | I | E | I | Q | F | N | N | A | G | F | I | S | G | A | S | I | Q | S | Y | L | L | E | K | S | R | V | V | F | Q | S | E | T | E | R | N | Y | H | I | F | Y | Q | L | L | A | G | A | T | A | E | E | K | K | A | L | H | L | A | G | P | E | S | F | N | Y | L | N | Q | S | G | C | V | D |
| Template Known Secondary structure |   |
 |  |  | S |  |  |  |  |  |  |  |  |  |
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
| T | T |
|
| S |
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  | T | T |
|
|
| T | T | S |
| T | T | T | T | T | S | S |
| S |
|
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
235 | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . |
|   |
|   |   |
264 | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | E | T | I | D | D | L | Q | D | Y | Q | E | T | L | K | A | M | R | V | I | G | L | G | Q | E | E | Q | D | Q | I | F | R | M | L | A | A | I | L | W | I | G | N | V | S | F | I | E | N | E | E | G | N | A | Q | V | R | D | T | S | V | T | D | F | V | A | Y | L | L | Q | I | D | S | Q | L | L | I | K | S | L | V |
| Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |
|
|
|
|   |   |   |   |
|   |   |   |
|
|
| Template Sequence |   |
I | K | G | V | S | D | E | D | E | F | K | I | T | R | Q | A | M | D | I | V | G | F | S | Q | E | E | Q | M | S | I | F | K | I | I | A | G | I | L | H | L | G | N | I | K | F | E | K | G | A | G | E | G | A | V | L | K | D | K | T | A | L | N | A | A | S | T | V | F | G | V | N | P | S | V | L | E | K | A | L | M |
| Template Known Secondary structure |   |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |
| T | T | S | S | S |
|  |  | S |
|
|  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
315 | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . |
|   |
|   |   |
344 | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | R | I | M | E | T | N | H | G | M | K | R | G | S | V | Y | H | V | P | L | N | I | V | Q | A | D | A | V | R | D | A | L | A | K | A | I | Y | N | N | L | F | D | W | I | V | S | R | V | N | K | S | L | Q | A | F | P | G | A | E | K | S | I | G | I | L | D | I | Y | G | F | E | I | F | E | H | N | S | F | E | Q |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|
|
|   |   |   |   |
|   |   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|
|
|
|
|   |
|
|   |   |
|
|   |
|
|
|   |   |
|
|   |   |
|   |   |   |   | . | . |   |   |   |
|
|
|
|
|
|   |
|
|
|   |   |   |   |
|
|
|
|
|
| Template Sequence |   |
E | P | R | I | L | A | G | . |
. |
. |
. |
. |
R | D | L | V | A | Q | H | L | N | V | E | K | S | S | S | S | R | D | A | L | V | K | A | L | Y | G | R | L | F | L | W | L | V | K | K | I | N | N | V | L | C | S | R | A | . |
. |
A | Y | F | I | G | V | L | D | I | S | G | F | E | I | F | K | V | N | S | F | E | Q |
| Template Known Secondary structure |   |
S |
|  |  |  | S | S | . | . | . | . | . | S |
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | S |  |  |  |  |  |  |  |
|
|
|
|
|
|
| S | S |
|
|  |  |  |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |
| . | . | . | . | . |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
395 | . | . | . | . | 400 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | |
|
. | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . |
|   |
|   |   |
424 | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
I | C | I | N | Y | V | N | E | K | L | Q | Q | I | F | I | Q | L | T | L | K | S | E | Q | E | T | Y | E | R | E | K | I | Q | W | T | P | I | K | Y | F | D | N | K | V | V | C | D | L | I | E | A | R | R | P | P | G | I | F | A | A | M | N | D | S | V | A | T | A | H | A | D | S | N | A | A | D | Q | A | F | A | Q |
| Query Conservation |   |
|
|
|
|   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|
|   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |   |   |
|   |
|
|   |   |
|   |
|   |
|
|
|   |
|
|
|
|
|   |   |   | . | . | . | . |   |   |   |
|
|   |   |   |
|   |
| Template Sequence |   |
L | C | I | N | Y | T | N | E | K | L | Q | Q | F | F | N | H | H | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | S | Q | A | T | I | D | L | I | D | G | R | Q | P | P | G | I | L | A | L | L | D | E | Q | S | V | F | . |
. |
. |
. |
P | N | A | T | D | N | T | L | I | T |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| T |  |  |  |  |  |  |  |  |
| S | S | S |
|
|  |  |  |  |  |  |  |  |  | T |
| . | . | . | . | T | T | S |
|  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|  |  |
|
|
| . | . | . | . |
|
|
|
|  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
469 | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | |
|
|
|
. | . | . | . | . | . | 520 | . | . | . |
|   |
|   |   |
504 | . | . | . | |
. | . | 510 | . | . | . | . | |
|
|
|
. | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  | . |  |
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
| . |
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | L | N | L | . |
F | T | T | N | P | H | F | . |
. |
. |
. |
D | L | R | S | N | K | F | V | I | K | H | Y | A | G | D | V | T | Y | D | I | D | G | I | T | D | K | N | K | D | Q | L | Q | K | D | L | V | E | L | I | G | T | T | T | N | T | F | L | A | T | I | F | P | D | T | V | D | R | E | S | K | R | R | P | P |
| Query Conservation |   |
  |   |   |   | . |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |
|   |
|   |
|   |
|
|   |
|   |
|   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
| Template Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|
|   |
|   |
|   |
|   |   |
|
|   |
|
|   |
|   |
|   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |
|   |   |
|
|   |   |   | . | . | . |   |   |   |   |   |   |   |
| Template Sequence |   |
K | L | H | S | H | F | S | K | K | N | A | K | Y | E | E | P | R | F | S | K | T | E | F | G | V | T | H | Y | A | G | Q | V | M | Y | E | I | Q | D | W | L | E | K | N | K | D | P | L | Q | Q | D | L | E | L | C | F | K | D | S | S | D | N | V | V | T | K | L | F | N | D | P | . |
. |
. |
N | I | A | S | R | F | I |
| Template Known Secondary structure |   |
 |  |  |  |  |  | T | T | T |
| T | T |  |  |
|
| T | T |
| S | S |
|  |  |  |
|
| S | S |
|
|
|  |  |
|
| T | T |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  | T | T |
| S |
|  |  |  |  |  |  |  |  |
| T | . | . | . | T | T | T |
|
|
|
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
| . | . | . |
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
546 | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | |
|
|
. | . | . | . | 620 | . | . |
|   |
|   |   |
579 | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
T | A | G | D | K | I | I | K | S | A | N | D | L | V | E | T | L | S | K | A | Q | P | S | Y | I | R | T | I | K | P | N | E | T | K | S | P | N | D | Y | D | D | R | Q | V | L | H | Q | I | K | Y | L | G | L | Q | E | N | V | R | I | R | R |
| Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |
|   |
|
|   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |   |
|
|
|
|
|
|
|
|
|   |   |
|   |   |   |   |
|
|   |   |   |
|   |   |
|
|
|   |   |
|
|
|
|   |   |   |   |
|
|
| Template Sequence |   |
T | V | A | A | Q | Y | K | E | Q | L | A | S | L | M | A | T | L | E | T | T | N | P | H | F | V | R | C | I | I | P | N | N | K | Q | L | P | A | K | L | E | D | K | V | V | L | D | Q | L | R | C | N | G | V | L | E | I | R | I | T | R | K |
| Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |  |  |  |
|  |  |  |  |
|
|
| T | T |
|
| S | S |
|
|
| T | T |  |  |  |  |  |  |  |  | T | T | T | T |
|
|  |  |  |  |
|
| Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
629 | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . |
|   |