Job Description O13559 Confidence 99.97% Date Mon Jul 2 19:10:15 BST 2012 Rank 30 Aligned Residues 349 % Identity 17% Template c2i4iA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent rna helicase ddx3x; PDBTitle: crystal structure of human dead-box rna helicase ddx3x Resolution 2.20 Å

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		357	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.																			.
Predicted Secondary structure																																																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		D	I	L	V	A	G	R	K	L	F	G	S	S	F	E	F	R	D	L	H	Q	L	R	L	C	H	E	I	Y	M	A	D	T	P	S	V	A	V	Q	A	P	P	G	Y	G	K	T	E	L	F	H	L	P	L	I	A	L	A	S	K	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	D
Query Conservation																																																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence										.			.	.																		.	.																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation										.			.	.																		.	.
Template Sequence		I	I	M	G	N	I	E	L	.	T	R	.	.	Y	T	R	P	T	P	V	Q	K	H	A	I	P	I	I	K	E	.	.	K	R	D	L	M	A	C	A	Q	T	G	S	G	K	T	A	A	F	L	L	P	I	L	S	Q	I	Y	S	D	G	P	G	E	A	L	R	A	M	K	E	N	G	R	Y	G	R	R	K
Template Known Secondary structure										.		T	.	.			S														T	.	.	T									T	T	S																														B	T	T	B	S		S
Template Predicted Secondary structure										.			.	.																		.	.
Template SS confidence
		190	.	.	.	.	.	.	.		.	.			200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.			.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.
		419	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.									.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Predicted Secondary structure																											.	.	.	.	.	.	.	.
Query SS confidence																											.	.	.	.	.	.	.	.
Query Sequence		V	K	Y	V	S	F	L	F	V	P	Y	T	V	L	L	A	N	C	M	I	R	L	S	R	C	.	.	.	.	.	.	.	.	G	C	L	N	V	A	P	V	R	N	F	I	E	E	G	C	D	G	V	T	D	L	Y	V	G	I	Y	D	D	L	A	S	T	N	F	T	D	R	I	A	A	W	E	N	I	V	E
Query Conservation																											.	.	.	.	.	.	.	.
Alig confidence																											.	.	.	.	.	.	.	.																																										.	.	.	.	.	.
Template Conservation																																																																												.	.	.	.	.	.
Template Sequence		Q	Y	P	I	S	L	V	L	A	P	T	R	E	L	A	V	Q	I	Y	E	E	A	R	K	F	S	Y	R	S	R	V	R	P	C	V	V	Y	G	G	A	D	I	G	Q	Q	I	R	D	L	E	R	G	C	H	L	L	V	A	T	P	G	R	L	V	D	M	M	E	R	G	K	I	G	L	.	.	.	.	.	.
Template Known Secondary structure		B			S						S	S																T	T	S	S								S	S	S										T	T			S															T	T	S	B			.	.	.	.	.	.
Template Predicted Secondary structure																																																																												.	.	.	.	.	.
Template SS confidence
		265	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.
		491	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.			.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.
Predicted Secondary structure																																							.	.
Query SS confidence																																							.	.
Query Sequence		C	T	F	R	T	N	N	V	K	L	G	Y	L	I	V	D	E	F	H	N	F	E	T	E	V	Y	R	Q	S	Q	F	G	G	I	T	N	L	.	.	D	F	D	A	F	E	K	A	I	F	L	S	G	T	A	P	E	A	V	A	D	A	A	L	Q	R	I	G	L	T	G	L	A	K	K	S	M	D	I	N	E
Query Conservation																																							.	.
Alig confidence		.	.	.	.	.	.	.																															.	.
Template Conservation		.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	D	F	C	K	Y	L	V	L	D	E	A	D	R	M	L	D	M	G	F	E	P	Q	I	R	R	I	V	E	Q	D	T	M	P	P	K	G	V	R	H	T	M	M	F	S	A	T	F	P	K	E	I	Q	M	L	A	R	D	F	L	D	E	Y	I	F	L	A	V	G	T	S	E	N	I
Template Known Secondary structure		.	.	.	.	.	.	.	T	T							S	S							T	T										T	S	S	S				B	T	T	B							S															S	S										S	S
Template Predicted Secondary structure		.	.	.	.	.	.	.
Template SS confidence
									339	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.
		569	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	K	R	S	E	D	L	S	R	G	L	S	S	Y	P	T	R	M	F	N	L	I	K	E	K	S	E	V	P	L	G	H	V	H	K	I	W	K	K	V	E	S	Q	P	E	E	A	L	K	L	L	L	A	L	F	E	I	E	P	E	S	K	A	I	V	V	A	S	T	T	N	E	V	E	E	L	A	C	S	W
Query Conservation
Alig confidence													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		T	Q	K	V	V	W	V	E	E	S	D	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	K	R	S	F	L	L	D	L	L	N	A	T	G	K	D	S	L	T	L	V	F	V	E	T	K	K	G	A	D	S	L	E	D	F	L
Template Known Secondary structure										G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.											T			T	T								S	S
Template Predicted Secondary structure													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		416	.	.	.	420	.	.	.	.	.	.																																			.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.
			649	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.		720	.	.	.	.	.	.
Predicted Secondary structure		.																																																																								.
Query SS confidence		.																																																																								.
Query Sequence		.	R	K	Y	F	R	V	V	W	I	H	G	K	L	G	A	A	E	K	V	S	R	T	K	E	F	V	T	D	G	S	M	R	V	L	I	G	T	K	L	V	T	E	G	I	D	I	K	Q	L	M	M	V	I	M	L	D	N	R	L	N	I	I	E	L	I	Q	G	V	G	R	L	.	R	D	G	G	L	C	Y
Query Conservation		.																																																																								.
Alig confidence		.																										.																																														.
Template Conservation																												.
Template Sequence		Y	H	E	G	Y	A	C	T	S	I	H	G	D	R	S	Q	R	D	R	E	E	A	L	H	Q	F	.	R	S	G	K	S	P	I	L	V	A	T	A	V	A	A	R	G	L	D	I	S	N	V	K	H	V	I	N	F	D	L	P	S	D	I	E	E	Y	V	H	R	I	G	R	T	G	R	N	L	G	L	A	T
Template Known Secondary structure				T	T								T	T	S													.			T	S	S											T	T	S											S	S			S	S									T	T	B
Template Predicted Secondary structure																												.
Template SS confidence
		462	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.		.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
		727	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	L	S	R	K	N	S	W	A	A	R	N	R	K	G	E	L	P	P	I	K	E	G	C	I	T	E	Q	V	R	E	F
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	F	F	N	E	R	N	I	N	I	T	K	D	L	L	D	L	L	V	E	A	K	Q	E	V	P	S	W	L	E	N	M
Template Known Secondary structure						G	G	G	G	G	G											T	T
Template Predicted Secondary structure
Template SS confidence
		543	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.