Missense3D predicts the structural changes introduced by an amino acid substitution and is applicable to analyse both PDB coordinates and homology-predicted structures.

Please cite: Ittisoponpisan, S., Islam, S.A., Khanna, T., Alhuzimi, E., David, A. & Sternberg, M.J.E. (2019)
Can Predicted Protein 3D Structures Provide Reliable Insights into whether Missense Variants Are Disease Associated? J. Mol. Biol. 431, 2197-2212.
https://doi.org/10.1016/j.jmb.2019.04.009

Missense3D predicts the structural changes introduced by an amino acid substitution and is applicable to analyse both PDB coordinates and homology-predicted structures.


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Variant information

Please select a valid amino acid.
Please select a valid amino acid.
Example

#PDB #Chain #Residue No. #WildtypeAA #MutantAA
P06280 3hg3 B 52 Cys Arg
P00918 2fos A 107 His Tyr
*Each column is separated by a space.

Example

#PDB #Chain #Residue No. #WildtypeAA #MutantAA
3hg3 B 52 Cys Arg
2fos A 107 His Tyr
*Each column is separated by a space.

3hg3 B 52 Cys Arg 2fos A 107 His Tyr
P06280 3hg3 B 52 Cys Arg P00918 2fos A 107 His Tyr

Medical Disclaimer: Missense3D is intended for purely research purposes. It should not be used for medical or professional advice or any clinical decision making.

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