Attention: Both Phyre and 3D-PSSM will be taken off-line for approximately 3 months.

The reason for this is the upcoming CASP7 protein structure prediction competition. We do not wish our systems to be used as part of 'meta-servers' which compile the results of multiple freely available servers on the web. The performance of such systems skews the scientific assessment of the quality of individual predictive methods and in our opinion detracts from the true aims of the CASP event.

We are sorry if this poses serious difficulties for any researchers. Any individual or group who is not connected with the upcoming CASP experiment and for whom our services are vital to their research is welcome to email me (l.a.kelley@imperial.ac.uk) if they wish to be exempted from this exclusion.

Access to the servers will be removed from May 5th 2006