Alignment of TRAD_HUMAN_whole with 1ucwA0

Alignment of TRAD_HUMAN_whole with 1ucwA0

PSSM Score Key
-10																			10

Bad																			Good

TRAD_H_PSS	Predicted Secondary Structure for your Sequence
TRAD_H_Seq	Your Sequence
1ucwA0_Seq	Library Sequence
1ucwA0_SS	Known Secondary Structure of the Library Sequence (Assigned by STRIDE)
CORE	A measure of the burial and number of contacts made by a residue. (9 very buried/making many contacts, 0 not buried/making few contacts

TRAD_H_PSS

C

C

C

C

C

C

C

H

H

H

H

E

E

E

E

E

E

E

E

E

C

.

.

.

.

H

H

H

H

H

H

H

H

C

C

C

C

C

C

H

.

.

.

.

.

H

H

H

H

H

TRAD_H_Seq

M

A

A

G

Q

N

G

H

E

E

W

V

G

S

A

Y

L

F

V

E

S

.

.

.

.

S

L

D

K

V

V

L

S

D

A

Y

A

H

P

Q

.

.

.

.

.

Q

K

V

A

V

-------

-

+

-

-

+

-

-

-

-

+

-

+

+

+

+

+

+

-

-

-

D

A

-

P

-

+

-

-

1ucwA0_Seq

.

.

.

.

T

D

K

L

T

S

L

R

Q

Y

T

T

V

V

A

D

T

G

D

I

A

A

M

K

L

Y

Q

P

Q

D

A

T

T

N

P

S

L

I

L

N

A

A

Q

I

P

E

1ucwA0_SS

.

.

.

.

C

E

H

H

H

H

H

H

C

C

C

E

E

E

E

E

C

C

C

H

H

H

H

H

H

H

C

C

C

E

E

E

C

C

H

H

H

H

H

H

H

H

C

C

H

H

CORE

.

.

.

.

0

0

0

3

0

0

7

0

0

0

2

0

5

1

5

0

0

3

0

1

0

0

4

0

0

0

0

2

0

0

6

1

3

0

0

0

0

3

0

0

2

3

0

0

0

0

TRAD_H_PSS

H

H

H

H

.

.

H

H

H

H

H

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

C

C

C

E

E

E

E

E

E

H

H

H

C

C

C

H

H

H

H

.

.

.

.

TRAD_H_Seq

Y

R

A

L

.

.

Q

A

A

L

A

E

S

G

G

S

P

D

V

L

Q

M

L

K

I

H

R

S

D

P

Q

L

I

V

Q

L

R

F

C

G

R

Q

P

C

G

R

.

.

.

.

-------

Y

R

L

+

A

-

+

-

-

-

-

-

S

-

D

-

-

Q

+

+

-

-

-

-

+

-

-

L

-

-

-

-

P

G

R

1ucwA0_Seq

Y

R

K

L

I

D

D

A

V

A

W

A

K

Q

Q

S

N

D

R

A

Q

Q

I

V

D

A

T

D

K

L

A

V

N

I

G

L

E

I

L

K

L

V

P

.

G

R

I

S

T

E

1ucwA0_SS

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

.

C

C

E

E

C

C

CORE

0

0

0

1

2

0

0

2

2

0

0

1

0

0

0

0

0

0

0

0

0

0

0

0

0

2

1

0

0

4

1

1

0

3

1

0

0

4

1

0

1

2

0

.

0

0

4

0

2

0

TRAD_H_PSS

.

.

.

H

H

H

H

H

H

H

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

E

E

E

E

E

C

C

C

H

H

H

H

H

H

H

C

C

C

C

TRAD_H_Seq

.

.

.

F

L

R

A

Y

R

E

G

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

H

S

V

P

L

Q

L

E

L

R

A

G

A

E

R

L

D

A

L

L

A

D

E

-------

-

L

-

-

-

E

-

S

-

-

-

-

L

-

L

-

-

-

+

-

+

-

A

-

-

-

-

E

1ucwA0_Seq

V

D

A

R

L

S

Y

D

T

E

A

S

I

A

K

A

K

R

L

I

K

L

Y

N

D

A

G

I

S

N

D

R

I

L

I

L

A

S

T

W

Q

G

I

R

A

A

E

Q

L

E

1ucwA0_SS

C

C

H

H

H

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

H

H

H

E

E

E

E

E

C

C

H

H

H

H

H

H

H

H

H

H

H

CORE

4

0

1

0

0

1

0

0

0

0

0

2

1

0

0

3

0

0

2

2

0

0

1

0

0

0

0

1

0

0

0

0

2

0

4

7

2

6

1

0

0

3

5

0

3

7

0

0

3

0

TRAD_H_PSS

H

H

H

H

H

H

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

E

E

E

E

E

E

E

C

C

.

.

.

C

C

C

C

C

C

C

C

C

C

C

C

C

C

TRAD_H_Seq

E

R

C

L

S

C

I

L

A

Q

Q

P

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

N

L

K

C

G

.

.

.

S

G

A

R

G

G

D

G

E

V

A

S

A

P

-------

+

-

+

C

-

L

-

-

-

-

-

-

G

-

-

-

-

+

+

-

-

A

P

1ucwA0_Seq

K

E

G

I

N

C

N

L

T

L

L

F

S

F

A

Q

A

R

A

C

A

E

A

G

V

F

L

I

S

P

F

V

G

R

I

L

D

W

Y

K

A

N

T

D

K

K

E

Y

A

P

1ucwA0_SS

H

H

C

C

C

E

E

E

E

E

E

C

C

H

H

H

H

H

H

H

H

H

H

C

C

C

E

E

E

E

E

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

C

CORE

0

0

0

2

0

4

0

9

0

2

8

0

0

0

1

0

7

0

2

8

1

0

1

0

6

0

0

9

0

4

0

7

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

TRAD_H_PSS

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

E

E

E

E

E

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

C

H

H

TRAD_H_Seq

L

Q

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

A

Q

T

F

L

F

Q

G

Q

P

V

V

N

R

P

L

S

L

K

D

Q

Q

T

F

A

R

S

V

G

L

K

-------

-

-

-

-

-

G

-

S

+

-

-

-

-

-

G

-

1ucwA0_Seq

A

E

D

P

G

V

V

S

V

S

E

I

Y

Q

Y

Y

K

E

H

G

Y

E

T

V

V

M

G

A

.

.

.

.

.

.

.

S

F

R

N

I

G

E

I

L

E

L

A

G

C

D

1ucwA0_SS

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

E

E

E

E

E

.

.

.

.

.

.

.

C

C

C

C

H

H

H

H

H

H

C

C

C

C

C

CORE

0

0

0

0

1

3

0

0

9

2

0

7

1

0

0

2

0

0

0

0

0

0

2

0

8

1

5

1

.

.

.

.

.

.

.

0

5

0

0

1

0

0

6

1

0

7

4

1

5

0

TRAD_H_PSS

H

.

.

.

.

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

TRAD_H_Seq

W

.

.

.

.

R

K

V

G

R

S

L

Q

R

G

C

R

A

L

R

D

P

A

L

D

S

L

A

Y

E

Y

E

R

E

G

L

Y

E

Q

A

F

Q

L

L

R

R

F

V

Q

A

-------

-

+

-

L

+

-

-

-

A

+

-

-

-

-

-

-

-

+

-

+

-

+

-

-

+

-

E

F

+

+

-

+

1ucwA0_Seq

R

L

T

I

A

P

A

L

L

K

E

L

A

E

S

E

G

A

I

E

R

K

L

S

Y

T

G

E

V

K

A

R

P

A

R

I

T

E

S

E

F

.

.

.

.

L

W

Q

H

N

1ucwA0_SS

E

E

E

E

C

H

H

H

H

H

H

H

H

H

C

E

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

.

.

.

.

H

H

H

H

H

CORE

0

6

1

6

0

0

0

2

4

0

0

5

1

0

0

0

0

0

2

0

0

0

5

0

0

0

0

0

0

0

0

0

0

0

0

1

0

0

0

0

1

.

.

.

.

0

0

0

0

0

TRAD_H_PSS

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

C

C

C

TRAD_H_Seq

E

G

R

R

A

T

L

Q

R

L

V

E

A

L

E

E

N

E

L

T

S

L

A

E

D

L

L

G

L

T

D

P

N

G

G

L

A

-------

+

-

+

-

-

V

+

-

L

E

+

-

A

-

D

-

L

-

+

-

-

G

-

L

-

1ucwA0_Seq

Q

D

.

.

.

.

.

P

M

A

V

D

K

L

A

E

G

.

I

R

K

F

A

I

D

Q

E

K

L

E

K

M

I

G

D

L

L

1ucwA0_SS

H

C

.

.

.

.

.

H

H

H

H

H

H

H

H

H

H

.

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

CORE

0

0

.

.

.

.

.

0

0

0

0

0

0

1

0

0

0

.

2

0

0

0

0

0

0

0

0

0

2

0

0

0

3

0

0

1

0