Alignment of TRAD_HUMAN_whole with 1uby-0

Alignment of TRAD_HUMAN_whole with 1uby-0

PSSM Score Key
-10																			10

Bad																			Good

TRAD_H_PSS	Predicted Secondary Structure for your Sequence
TRAD_H_Seq	Your Sequence
1uby-0_Seq	Library Sequence
1uby-0_SS	Known Secondary Structure of the Library Sequence (Assigned by STRIDE)
CORE	A measure of the burial and number of contacts made by a residue. (9 very buried/making many contacts, 0 not buried/making few contacts

TRAD_H_PSS

C

.

C

C

C

C

C

C

H

H

H

H

E

E

E

E

E

E

E

E

E

C

H

H

H

H

H

H

.

.

.

H

H

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

TRAD_H_Seq

M

.

A

A

G

Q

N

G

H

E

E

W

V

G

S

A

Y

L

F

V

E

S

S

L

D

K

V

V

.

.

.

L

S

D

A

Y

A

H

P

Q

Q

K

V

A

V

Y

R

A

L

Q

-------

-

-

+

-

E

E

+

V

G

-

-

+

V

+

D

-

+

H

P

-

-

-

A

V

-

R

-

+

1uby-0_Seq

S

P

V

V

V

E

R

E

R

E

E

F

V

G

.

.

.

.

.

.

.

.

F

F

P

Q

I

V

R

D

L

T

E

D

G

I

G

H

P

E

V

G

D

A

V

A

R

L

K

E

1uby-0_SS

C

H

H

H

H

H

H

H

H

H

H

H

H

H

.

.

.

.

.

.

.

.

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

CORE

0

0

0

0

0

0

0

0

0

0

0

1

0

0

.

.

.

.

.

.

.

.

1

1

0

0

4

1

0

0

5

1

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

2

0

0

TRAD_H_PSS

H

H

.

.

H

H

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

.

.

C

C

C

E

E

E

E

E

E

H

H

H

C

C

C

H

H

H

H

H

H

H

H

H

H

H

TRAD_H_Seq

A

A

.

.

L

A

E

S

G

G

S

P

D

V

L

Q

M

L

K

I

H

R

.

.

S

D

P

Q

L

I

V

Q

L

R

F

C

G

R

Q

P

C

G

R

F

L

R

A

Y

R

E

-------

-

-

A

-

G

-

-

-

-

-

L

-

+

-

-

R

S

+

P

G

+

-

-

-

-

+

-

+

A

-

-

-

1uby-0_Seq

V

L

Q

Y

N

A

P

G

G

K

C

N

R

G

L

T

V

V

A

A

Y

R

E

L

S

G

P

.

.

.

.

.

.

.

.

.

G

Q

K

D

A

E

S

L

R

C

A

L

A

V

1uby-0_SS

H

H

H

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

.

.

.

.

.

.

.

.

.

C

C

C

C

H

H

H

H

H

H

H

H

H

H

CORE

1

5

0

0

0

4

0

0

0

0

0

0

0

1

0

1

9

2

0

4

1

0

0

3

0

0

0

.

.

.

.

.

.

.

.

.

0

0

0

0

0

0

0

0

0

2

5

1

3

9

TRAD_H_PSS

C

.

.

C

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

E

E

E

E

E

C

.

.

.

.

.

.

C

C

H

H

H

H

.

.

H

H

H

C

C

C

C

TRAD_H_Seq

G

.

.

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

H

S

V

P

L

Q

L

E

L

R

.

.

.

.

.

.

A

G

A

E

R

L

.

.

D

A

L

L

A

D

E

-------

G

-

S

-

-

-

L

-

G

-

-

-

-

L

L

-

-

1uby-0_Seq

G

W

C

I

E

L

F

Q

A

A

S

L

V

A

D

D

I

M

D

Q

S

L

T

R

R

G

Q

L

C

W

Y

K

K

E

G

V

G

L

D

A

I

N

D

S

F

L

L

E

S

S

1uby-0_SS

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

E

E

C

C

E

E

C

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

CORE

2

0

3

4

0

8

1

0

3

2

0

0

2

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

1

0

0

0

1

0

0

4

0

0

4

TRAD_H_PSS

.

H

H

H

H

H

H

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

E

E

E

E

.

.

.

.

.

.

E

E

E

C

C

C

C

C

C

C

C

C

C

C

C

TRAD_H_Seq

.

E

R

C

L

S

C

I

L

A

Q

Q

P

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

.

.

.

.

.

.

N

L

K

C

G

S

G

A

R

G

G

D

G

E

V

-------

-

R

-

L

-

-

-

-

Q

+

P

L

-

-

-

-

-

-

-

-

-

-

1uby-0_Seq

V

Y

R

V

L

K

K

Y

C

R

Q

R

P

Y

Y

V

H

L

L

E

L

F

L

Q

T

A

Y

Q

T

E

L

G

Q

M

L

D

L

I

T

A

P

V

S

K

V

D

L

S

H

F

1uby-0_SS

H

H

H

H

H

H

H

H

H

H

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

C

C

C

C

CORE

4

0

0

5

5

0

0

0

3

0

0

0

0

0

0

0

0

6

1

0

2

4

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

1

0

0

0

0

0

0

1

0

0

1

TRAD_H_PSS

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

H

H

H

H

H

H

H

H

E

TRAD_H_Seq

A

S

A

P

L

Q

X

X

X

X

X

X

X

X

X

X

X

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

X

X

X

X

X

X

A

Q

T

-------

-

-

-

-

-

1uby-0_Seq

S

E

E

R

Y

K

A

I

V

K

Y

K

T

A

F

Y

S

F

Y

L

P

V

A

A

A

M

Y

M

V

G

I

D

S

K

E

E

H

E

N

A

K

A

I

L

L

E

M

G

E

Y

1uby-0_SS

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

CORE

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

1

0

2

2

4

0

8

5

2

0

5

1

0

2

0

0

0

0

0

0

0

0

2

0

0

1

3

0

0

2

0

0

0

TRAD_H_PSS

E

E

E

E

.

.

.

.

.

.

.

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

C

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

TRAD_H_Seq

F

L

F

Q

.

.

.

.

.

.

.

G

Q

P

V

V

N

R

P

L

S

L

K

D

Q

Q

T

F

A

R

S

V

G

L

K

W

R

K

V

G

R

S

L

Q

R

G

C

R

A

L

-------

F

-

-

Q

G

P

-

+

-

-

-

-

D

-

-

-

-

-

W

-

V

-

L

Q

R

-

1uby-0_Seq

F

Q

I

Q

D

D

Y

L

D

C

F

G

D

P

A

L

T

G

A

V

G

.

T

D

.

.

.

I

Q

D

N

K

C

.

S

W

.

L

V

V

Q

C

L

Q

R

.

.

.

.

V

1uby-0_SS

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

C

C

C

.

C

C

.

.

.

C

C

C

C

C

C

.

C

H

.

H

H

H

H

H

H

H

H

.

.

.

.

C

CORE

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

.

0

0

.

.

.

1

0

0

0

0

1

.

0

0

.

0

1

1

0

1

1

0

0

.

.

.

.

0

TRAD_H_PSS

C

C

C

C

C

C

C

H

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

.

.

.

.

.

.

.

H

H

H

H

H

H

H

TRAD_H_Seq

R

D

P

A

L

D

S

L

A

Y

E

Y

E

R

E

G

L

Y

E

Q

A

F

Q

L

L

R

R

F

V

Q

A

E

G

R

R

A

.

.

.

.

.

.

.

T

L

Q

R

L

V

E

-------

-

-

-

-

L

-

-

-

Y

-

R

-

E

-

-

-

-

-

+

-

-

-

R

-

A

+

-

R

L

E

1uby-0_Seq

T

P

E

Q

R

Q

L

L

E

D

N

Y

G

R

K

E

.

P

E

K

V

A

K

V

K

E

L

Y

E

A

V

G

M

R

A

A

F

Q

Q

Y

E

E

S

S

Y

R

R

L

Q

E

1uby-0_SS

C

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

.

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

CORE

0

0

0

0

0

0

0

1

0

0

0

0

0

0

0

0

.

0

0

0

0

0

0

1

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

1

0

0

TRAD_H_PSS

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

.

C

C

C

C

C

TRAD_H_Seq

A

L

E

E

N

E

L

T

S

L

A

E

D

L

L

G

L

T

D

P

.

N

G

G

L

A

-------

+

E

-

-

-

-

-

E

-

+

L

G

L

-

-

-

-

-

-

-

-

1uby-0_Seq

L

I

E

K

H

S

N

R

L

P

K

E

I

F

L

G

L

A

Q

K

I

Y

K

R

Q

K

1uby-0_SS

H

H

H

H

H

H

C

C

C

C

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

CORE

0

0

0

0

0

0

0

0

2

0

0

0

2

2

0

0

3

1

0

0

1

0

0

0

0

0