Alignment of TRAD_HUMAN_whole with 1nsyA0

Alignment of TRAD_HUMAN_whole with 1nsyA0

PSSM Score Key
-10																			10

Bad																			Good

TRAD_H_PSS	Predicted Secondary Structure for your Sequence
TRAD_H_Seq	Your Sequence
1nsyA0_Seq	Library Sequence
1nsyA0_SS	Known Secondary Structure of the Library Sequence (Assigned by STRIDE)
CORE	A measure of the burial and number of contacts made by a residue. (9 very buried/making many contacts, 0 not buried/making few contacts

TRAD_H_PSS

C

C

C

C

C

C

C

H

H

H

H

E

E

E

E

E

E

E

E

E

C

H

H

H

H

H

H

H

H

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

TRAD_H_Seq

M

A

A

G

Q

N

G

H

E

E

W

V

G

S

A

Y

L

F

V

E

S

S

L

D

K

V

V

L

S

D

A

Y

A

H

P

Q

Q

K

V

A

V

Y

R

A

L

Q

A

A

L

A

-------

S

+

-

+

+

-

+

-

P

+

-

-

+

-

+

+

+

-

+

+

1nsyA0_Seq

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

S

M

Q

E

K

I

M

R

E

L

H

V

K

P

S

I

D

P

K

Q

E

.

.

I

E

D

R

V

N

1nsyA0_SS

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

C

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

H

H

H

H

.

.

H

H

H

H

H

H

CORE

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

0

0

0

0

0

2

0

0

0

3

0

3

0

0

0

1

0

0

0

0

0

.

.

2

0

0

0

2

0

TRAD_H_PSS

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

C

C

C

E

E

E

E

E

E

H

H

H

C

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

H

H

H

H

TRAD_H_Seq

E

S

G

G

S

P

D

V

L

Q

M

L

K

I

H

R

S

D

P

Q

L

I

V

Q

L

R

F

C

G

R

Q

P

C

G

R

F

L

R

A

Y

R

E

G

X

X

X

X

X

X

X

-------

+

L

+

-

-

-

-

+

+

-

+

+

-

+

-

G

-

Q

-

-

-

L

-

+

+

-

1nsyA0_Seq

F

.

.

.

.

.

.

.

L

K

Q

Y

V

K

K

T

G

A

K

G

F

V

L

G

I

.

.

S

G

G

Q

D

.

.

S

T

L

A

G

R

L

.

.

.

.

.

A

Q

L

A

1nsyA0_SS

H

.

.

.

.

.

.

.

H

H

H

H

H

H

H

H

C

C

C

E

E

E

E

E

C

.

.

C

C

C

H

H

.

.

H

H

H

H

H

H

H

.

.

.

.

.

H

H

H

H

CORE

1

.

.

.

.

.

.

.

9

0

0

0

5

0

0

0

0

3

0

4

8

3

7

1

5

.

.

0

1

0

0

0

.

.

3

2

3

6

4

0

5

.

.

.

.

.

9

0

1

5

TRAD_H_PSS

H

H

H

H

H

H

H

C

C

C

C

C

C

E

E

E

E

E

C

C

C

H

H

H

H

H

H

H

C

C

C

C

H

H

H

H

H

H

H

H

H

C

C

C

C

C

H

H

H

H

TRAD_H_Seq

X

X

X

X

X

X

X

X

X

H

S

V

P

L

Q

L

E

L

R

A

G

A

E

R

L

D

A

L

L

A

D

E

E

R

C

L

S

C

I

L

A

Q

Q

P

X

X

X

X

X

X

-------

-

-

+

-

+

-

L

-

-

G

+

+

D

E

+

+

-

-

-

+

-

P

1nsyA0_Seq

V

E

S

I

R

E

E

G

G

D

A

Q

F

I

A

V

R

L

P

H

G

.

.

.

.

.

.

T

Q

Q

D

E

D

D

A

Q

L

A

L

K

F

I

K

P

D

K

S

W

K

F

1nsyA0_SS

H

H

H

H

H

H

H

C

C

C

C

E

E

E

E

E

E

C

C

C

C

.

.

.

.

.

.

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

E

E

E

E

C

CORE

5

0

0

1

0

0

0

0

0

0

3

0

7

2

3

2

0

1

0

0

0

.

.

.

.

.

.

0

0

0

0

0

0

0

0

0

0

3

2

0

2

3

0

1

0

0

1

0

0

0

TRAD_H_PSS

H

H

H

H

H

H

E

E

E

E

E

E

E

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

TRAD_H_Seq

X

X

X

X

X

X

X

X

X

X

N

L

K

C

G

S

G

A

R

G

G

D

G

E

V

A

S

A

P

L

Q

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

A

Q

-------

-

-

S

-

+

+

+

-

-

+

-

+

+

Q

1nsyA0_Seq

D

I

K

S

T

V

.

.

.

.

.

.

S

A

F

S

D

Q

Y

Q

Q

E

T

G

D

Q

L

T

D

F

N

K

G

N

V

K

A

R

T

R

M

I

A

Q

Y

A

I

G

G

Q

1nsyA0_SS

C

H

H

H

H

H

.

.

.

.

.

.

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

CORE

0

0

0

0

0

0

.

.

.

.

.

.

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

2

1

0

0

TRAD_H_PSS

E

.

.

E

E

E

E

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

C

C

C

C

C

C

C

C

C

C

.

.

C

C

H

H

.

H

H

H

H

H

H

C

C

H

TRAD_H_Seq

T

.

.

F

L

F

Q

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

G

Q

P

V

V

N

R

P

L

S

.

.

L

K

D

Q

.

Q

T

F

A

R

S

V

G

L

-------

+

+

-

+

G

-

-

+

+

+

P

L

-

K

+

Q

T

-

+

+

G

+

1nsyA0_Seq

E

G

L

L

V

L

G

T

D

H

A

A

E

A

V

T

G

F

F

T

K

Y

G

D

G

G

A

D

L

L

.

P

L

T

G

L

T

K

R

Q

G

R

T

L

L

K

E

L

G

A

1nsyA0_SS

H

C

C

E

E

E

C

C

C

C

H

H

H

H

H

C

C

C

C

C

C

C

C

C

C

C

C

C

E

C

.

C

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

CORE

0

1

3

5

1

9

3

3

0

0

4

2

0

1

3

1

0

0

0

0

0

0

0

0

0

0

1

0

6

0

.

4

3

0

1

1

2

0

0

0

1

0

0

2

2

0

0

3

0

1

TRAD_H_PSS

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

TRAD_H_Seq

K

W

R

K

V

G

R

S

L

Q

R

G

C

R

A

L

R

D

P

A

L

D

S

L

A

Y

E

Y

E

R

E

G

L

Y

E

Q

A

F

Q

L

L

R

R

F

V

Q

A

E

G

R

-------

-

R

-

+

+

-

-

-

A

-

-

-

+

-

-

-

+

-

E

-

E

-

-

-

-

Y

+

+

+

-

-

-

+

1nsyA0_Seq

P

.

.

.

.

E

R

L

Y

L

K

E

P

T

A

D

L

L

D

E

K

P

Q

Q

S

D

E

T

E

L

G

I

S

Y

D

.

.

.

.

E

I

D

D

Y

L

E

G

K

E

V

1nsyA0_SS

C

.

.

.

.

H

H

H

H

H

C

C

C

E

C

C

C

C

C

C

C

C

C

C

E

H

H

H

H

H

C

C

C

H

H

.

.

.

.

H

H

H

H

H

H

H

C

C

C

C

CORE

0

.

.

.

.

0

0

2

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

1

0

0

0

.

.

.

.

0

2

0

0

0

4

0

0

0

0

0

TRAD_H_PSS

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

C

C

C

TRAD_H_Seq

R

A

T

L

Q

R

L

V

E

A

L

E

E

N

E

L

T

S

L

A

E

D

L

L

G

L

T

D

P

N

G

G

L

A

-------

-

A

-

+

+

+

-

+

E

-

+

-

+

-

+

-

-

-

-

+

-

+

-

-

-

-

-

-

1nsyA0_Seq

S

A

K

V

S

E

A

L

E

K

R

Y

S

.

.

.

M

T

E

H

K

R

Q

V

P

A

S

M

F

D

D

W

W

K

1nsyA0_SS

C

H

H

H

H

H

H

H

H

H

H

H

H

.

.

.

H

H

H

H

H

C

C

C

C

E

C

C

C

C

C

C

C

C

CORE

0

0

0

0

0

0

0

2

0

0

0

0

0

.

.

.

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0