Alignment of TRAD_HUMAN_whole with 1finC0

Alignment of TRAD_HUMAN_whole with 1finC0

PSSM Score Key
-10																			10

Bad																			Good

TRAD_H_PSS	Predicted Secondary Structure for your Sequence
TRAD_H_Seq	Your Sequence
1finC0_Seq	Library Sequence
1finC0_SS	Known Secondary Structure of the Library Sequence (Assigned by STRIDE)
CORE	A measure of the burial and number of contacts made by a residue. (9 very buried/making many contacts, 0 not buried/making few contacts

TRAD_H_PSS

C

C

.

.

.

.

.

.

.

.

.

C

C

C

C

C

H

H

H

H

E

E

E

E

E

E

E

E

E

C

H

H

H

H

H

H

.

.

.

.

H

H

C

C

C

C

C

C

H

H

TRAD_H_Seq

M

A

.

.

.

.

.

.

.

.

.

A

G

Q

N

G

H

E

E

W

V

G

S

A

Y

L

F

V

E

S

S

L

D

K

V

V

.

.

.

.

L

S

D

A

Y

A

H

P

Q

Q

-------

M

-

G

-

G

-

Y

+

-

+

-

-

+

V

V

+

+

-

1finC0_Seq

M

E

N

F

Q

K

V

E

K

I

G

E

G

T

Y

G

.

.

.

.

.

.

V

V

Y

K

A

R

N

K

L

T

G

E

V

V

A

L

K

K

I

R

L

D

T

E

T

E

G

V

1finC0_SS

C

C

C

E

E

E

E

E

E

E

E

C

C

C

C

C

.

.

.

.

.

.

C

E

E

E

E

E

E

C

C

C

C

C

E

E

E

E

E

E

E

C

C

E

C

C

C

C

E

C

CORE

1

0

0

2

0

0

0

0

0

0

0

0

0

0

0

0

.

.

.

.

.

.

0

1

0

0

2

0

0

0

0

0

0

0

0

2

1

2

0

0

2

0

1

0

0

0

0

0

0

1

TRAD_H_PSS

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

C

C

C

C

E

E

E

E

E

E

H

H

H

C

C

C

H

H

H

H

H

H

TRAD_H_Seq

K

V

A

V

Y

R

A

L

Q

A

A

L

A

E

S

G

G

S

P

D

V

L

Q

M

L

K

I

H

R

S

D

P

Q

L

I

V

Q

L

R

F

C

G

R

Q

P

C

G

R

F

L

-------

+

R

+

L

-

-

+

P

+

+

+

L

-

+

+

+

-

L

+

-

+

-

F

+

+

+

-

+

1finC0_Seq

P

S

T

A

I

R

.

.

E

I

S

L

L

K

E

L

N

H

P

N

I

V

K

L

L

D

V

I

H

T

E

N

K

L

Y

L

V

F

E

F

L

H

.

.

.

.

Q

D

L

K

1finC0_SS

C

H

H

H

H

H

.

.

H

H

H

H

H

H

C

C

C

C

C

C

E

C

C

E

E

E

E

E

E

C

C

C

C

E

E

E

E

E

E

C

C

C

.

.

.

.

E

E

H

H

CORE

0

0

0

2

0

0

.

.

0

2

0

1

3

0

0

4

0

0

0

0

6

2

0

2

1

0

2

1

0

0

0

0

0

3

0

2

3

2

0

0

1

0

.

.

.

.

0

0

8

0

TRAD_H_PSS

H

H

H

H

H

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

E

E

E

E

E

C

C

C

H

H

H

H

H

H

H

C

C

C

C

H

H

H

H

H

TRAD_H_Seq

R

A

Y

R

E

G

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

H

S

V

P

L

Q

L

E

L

R

A

G

A

E

R

L

D

A

L

L

A

D

E

E

R

C

L

S

-------

-

+

+

+

-

L

+

L

+

-

C

-

S

1finC0_Seq

K

F

M

D

A

S

A

L

T

G

I

P

L

P

L

I

K

S

Y

L

.

.

.

.

.

.

.

.

.

.

.

.

.

.

F

Q

L

L

Q

G

L

.

.

.

.

A

F

C

H

S

1finC0_SS

H

H

H

H

H

C

C

C

C

C

C

C

H

H

H

H

H

H

H

H

.

.

.

.

.

.

.

.

.

.

.

.

.

.

H

H

H

H

H

H

H

.

.

.

.

H

H

H

H

H

CORE

0

1

1

0

0

0

0

0

0

0

4

0

2

0

0

3

0

0

1

8

.

.

.

.

.

.

.

.

.

.

.

.

.

.

1

0

8

9

0

2

8

.

.

.

.

3

1

5

0

0

TRAD_H_PSS

H

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

E

E

E

E

.

.

.

.

.

E

E

E

C

C

C

C

C

C

C

C

C

C

C

C

C

C

.

.

.

.

C

TRAD_H_Seq

C

I

L

A

Q

Q

P

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

.

.

.

.

.

N

L

K

C

G

S

G

A

R

G

G

D

G

E

V

A

S

.

.

.

.

A

-------

-

-

-

-

-

-

-

+

-

G

+

-

R

-

-

E

V

+

A

1finC0_Seq

H

R

V

L

H

R

D

L

K

P

Q

N

L

L

I

N

T

E

G

A

I

K

L

A

D

F

G

L

A

R

A

F

G

V

P

V

R

T

Y

T

H

E

V

V

T

L

W

Y

R

A

1finC0_SS

H

C

E

E

C

C

C

C

C

H

H

H

E

E

E

E

C

C

C

E

E

E

E

C

C

C

C

C

C

E

E

C

C

C

C

C

E

C

C

C

C

C

C

C

C

H

H

H

C

C

CORE

0

0

3

0

0

0

0

8

0

2

0

0

9

1

2

0

0

0

0

0

5

0

9

1

0

3

0

0

1

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

TRAD_H_PSS

C

.

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

E

E

E

E

E

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

H

H

H

.

.

.

TRAD_H_Seq

P

.

L

Q

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

X

A

Q

T

F

L

F

Q

G

Q

P

V

V

N

R

P

L

S

L

K

D

Q

Q

T

F

A

R

.

.

.

-------

P

-

-

-

-

-

+

+

-

+

+

+

-

+

-

+

+

+

+

+

+

R

1finC0_Seq

P

E

I

L

L

G

C

K

Y

Y

S

T

A

V

D

I

W

S

L

G

C

I

F

A

E

M

V

T

R

R

A

L

.

.

.

F

P

G

D

S

E

I

D

Q

L

F

R

I

F

R

1finC0_SS

H

H

H

H

H

C

C

C

E

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

.

.

.

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

CORE

0

0

0

0

1

0

0

0

0

0

0

0

0

0

1

7

0

2

9

3

2

5

6

3

0

4

3

0

0

0

0

3

.

.

.

1

0

0

0

0

0

0

0

0

1

0

0

1

0

0

TRAD_H_PSS

H

C

C

H

H

H

H

H

H

H

H

H

H

H

H

C

C

.

.

.

C

C

C

C

C

C

C

C

C

C

H

H

H

H

C

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

TRAD_H_Seq

S

V

G

L

K

W

R

K

V

G

R

S

L

Q

R

G

C

.

.

.

R

A

L

R

D

P

A

L

D

S

L

A

Y

E

Y

E

R

E

G

L

Y

E

Q

A

F

Q

L

L

R

R

-------

-

-

G

-

+

+

V

-

+

-

-

-

+

+

+

A

+

-

+

-

-

-

E

+

+

L

L

+

+

1finC0_Seq

T

L

G

T

P

D

E

V

V

W

P

G

V

T

S

M

P

D

Y

K

P

S

F

P

K

W

A

R

Q

D

F

S

K

V

V

P

P

L

D

.

.

E

D

G

R

S

L

L

S

Q

1finC0_SS

H

H

C

C

C

C

C

C

C

C

C

C

H

H

H

C

C

C

C

C

C

C

C

C

C

C

C

C

C

C

H

H

H

H

C

C

C

C

C

.

.

H

H

H

H

H

H

H

H

H

CORE

1

2

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

1

0

0

0

0

0

0

0

1

0

0

1

2

0

0

3

0

.

.

0

0

1

0

0

7

4

0

0

TRAD_H_PSS

H

H

H

H

C

.

C

C

C

C

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

H

C

C

C

C

C

C

C

C

.

C

C

TRAD_H_Seq

F

V

Q

A

E

.

G

R

R

A

T

L

Q

R

L

V

E

A

L

E

E

N

E

L

T

S

L

A

E

D

L

L

G

L

T

D

P

N

G

G

.

L

A

-------

-

+

-

+

-

+

R

-

+

+

+

-

+

-

+

T

+

P

+

-

-

1finC0_Seq

M

L

H

Y

D

P

N

K

R

I

S

A

.

.

.

.

.

.

.

.

.

K

A

A

L

A

H

P

.

F

F

Q

D

V

T

K

P

V

P

H

L

R

L

1finC0_SS

H

H

C

C

C

C

C

C

C

C

C

H

.

.

.

.

.

.

.

.

.

H

H

H

H

H

C

H

.

H

H

C

C

C

C

C

C

C

C

C

C

C

C

CORE

8

3

0

0

0

0

0

0

0

6

0

8

.

.

.

.

.

.

.

.

.

0

0

8

2

0

0

0

.

3

4

0

0

0

0

0

0

0

0

0

1

0

0